All airlines flying from Knoxville (TYS) to Chicago O'Hare (ORD).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Mon,Thu,Fri,Sun 16:56 Knoxville (TYS) 18:02 Chicago O'Hare (ORD) 3
American Airlines AA 5217 Non-stop Canadair CRJ 700 (CR7) 2:06 Effective 2026-02-22 through 2026-03-06
Tue,Wed 17:08 Knoxville (TYS) 18:14 Chicago O'Hare (ORD) 3
American Airlines AA 5217 Non-stop Canadair CRJ 700 (CR7) 2:06 Effective 2026-02-17 through 2026-03-04
Sun 11:13 Knoxville (TYS) 12:16 Chicago O'Hare (ORD) 3
American Airlines AA 5222 Non-stop Canadair CRJ 700 (CR7) 2:03 Effective 2026-02-22 through 2026-03-01
Daily 17:37 Knoxville (TYS) 18:34 Chicago O'Hare (ORD) 3
American Airlines AA 5225 Non-stop Canadair CRJ 700 (CR7) 1:57 Effective 2026-08-05 through 2026-09-08
Mon-Fri,Sun 16:02 Knoxville (TYS) 17:09 Chicago O'Hare (ORD) 3
American Airlines AA 5228 Non-stop Canadair CRJ 700 (CR7) 2:07 Effective 2026-03-08 through 2026-04-06
Daily 18:52 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 5302 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2026-07-02 through 2026-08-04
Daily 18:56 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 5302 Non-stop Canadair CRJ 700 (CR7) 1:54 Effective 2026-05-21 through 2026-07-01
Daily 07:40 Knoxville (TYS) 08:48 Chicago O'Hare (ORD) 3
American Airlines AA 5318 Non-stop Canadair CRJ 700 (CR7) 2:08 Effective 2026-03-08 through 2026-04-06
Mon,Thu-Sun 07:40 Knoxville (TYS) 08:52 Chicago O'Hare (ORD) 3
American Airlines AA 5325 Non-stop Canadair CRJ 700 (CR7) 2:12 Effective 2026-02-13 through 2026-03-07
Tue,Wed 07:42 Knoxville (TYS) 08:54 Chicago O'Hare (ORD) 3
American Airlines AA 5325 Non-stop Canadair CRJ 700 (CR7) 2:12 Effective 2026-02-17 through 2026-03-04
Daily 07:48 Knoxville (TYS) 08:50 Chicago O'Hare (ORD) 3
American Airlines AA 5325 Non-stop Canadair CRJ 700 (CR7) 2:02 Valid until 2026-01-05
Thu 08:13 Knoxville (TYS) 09:25 Chicago O'Hare (ORD) 3
American Airlines AA 5325 Non-stop Canadair CRJ 700 (CR7) 2:12 Operates only on 2026-02-12
Daily 18:54 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 5338 Non-stop Canadair CRJ 700 (CR7) 1:56 Effective from 2026-10-05
Daily 17:08 Knoxville (TYS) 18:20 Chicago O'Hare (ORD) 3
American Airlines AA 5344 Non-stop Canadair CRJ 700 (CR7) 2:12 Valid until 2026-01-05
Sat 16:44 Knoxville (TYS) 17:55 Chicago O'Hare (ORD) 3
American Airlines AA 5355 Non-stop Canadair CRJ 700 (CR7) 2:11 Operates only on 2026-01-10
Sat 16:44 Knoxville (TYS) 17:55 Chicago O'Hare (ORD) 3
American Airlines AA 5355 Non-stop Canadair CRJ 700 (CR7) 2:11 Effective 2026-01-24 through 2026-02-07
Mon-Fri,Sun 17:15 Knoxville (TYS) 18:26 Chicago O'Hare (ORD) 3
American Airlines AA 5355 Non-stop Canadair CRJ 700 (CR7) 2:11 Effective 2026-01-06 through 2026-02-11
Daily 08:05 Knoxville (TYS) 09:09 Chicago O'Hare (ORD) 3
American Airlines AA 5379 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2026-08-05 through 2026-09-08
Daily 08:06 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
American Airlines AA 5379 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2026-05-21 through 2026-07-01
Daily 08:06 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
American Airlines AA 5379 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2026-09-09 through 2026-10-04
Daily 08:11 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
American Airlines AA 5379 Non-stop Canadair CRJ 700 (CR7) 1:59 Effective 2026-07-02 through 2026-08-04
Daily 13:22 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
American Airlines AA 5420 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2026-07-02 through 2026-08-04
Daily 13:27 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
American Airlines AA 5434 Non-stop Canadair CRJ 700 (CR7) 1:53 Effective 2026-05-21 through 2026-07-01
Daily 15:03 Knoxville (TYS) 16:10 Chicago O'Hare (ORD) 3
American Airlines AA 5467 Non-stop Canadair CRJ 700 (CR7) 2:07 Effective 2026-04-07 through 2026-05-20
Daily 11:34 Knoxville (TYS) 12:40 Chicago O'Hare (ORD) 3
American Airlines AA 5468 Non-stop Canadair CRJ 700 (CR7) 2:06 Effective 2026-04-07 through 2026-05-20
Daily 20:23 Knoxville (TYS) 21:30 Chicago O'Hare (ORD) 3
American Airlines AA 5469 Non-stop Canadair CRJ 700 (CR7) 2:07 Effective 2026-04-07 through 2026-05-20
Daily 11:42 Knoxville (TYS) 12:40 Chicago O'Hare (ORD) 3
American Airlines AA 5592 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2026-03-08 through 2026-04-06
Mon-Fri,Sun 17:29 Knoxville (TYS) 18:27 Chicago O'Hare (ORD) 2
United Airlines UA 5785 Non-stop Canadair CRJ 550 (CR5) 1:58 Effective 2026-01-06 through 2026-02-02
Tue 17:29 Knoxville (TYS) 18:30 Chicago O'Hare (ORD) 2
United Airlines UA 5785 Non-stop Embraer EMB 175 (E7W) 2:01 Operates only on 2026-02-03
Mon-Fri,Sun 17:29 Knoxville (TYS) 18:27 Chicago O'Hare (ORD) 2
United Airlines UA 5785 Non-stop Canadair CRJ 550 (CR5) 1:58 Effective 2026-02-04 through 2026-02-11
Daily 14:00 Knoxville (TYS) 14:55 Chicago O'Hare (ORD) 2
United Airlines UA 5844 Non-stop Embraer EMB 175 (E7W) 1:55 Effective from 2026-05-21
Daily 08:26 Knoxville (TYS) 09:23 Chicago O'Hare (ORD) 2
United Airlines UA 5876 Non-stop Canadair CRJ 550 (CR5) 1:57 Effective from 2026-10-25
Daily 10:49 Knoxville (TYS) 11:53 Chicago O'Hare (ORD) 2
United Airlines UA 5921 Non-stop Embraer EMB 175 (E7W) 2:04 Effective 2026-04-30 through 2026-05-20
Daily 10:50 Knoxville (TYS) 11:54 Chicago O'Hare (ORD) 2
United Airlines UA 5921 Non-stop Embraer EMB 175 (E7W) 2:04 Effective 2026-03-29 through 2026-04-29
Daily 10:50 Knoxville (TYS) 11:47 Chicago O'Hare (ORD) 2
United Airlines UA 5921 Non-stop Canadair CRJ 550 (CR5) 1:57 Effective from 2026-05-21
Mon-Fri,Sun 10:53 Knoxville (TYS) 12:00 Chicago O'Hare (ORD) 2
United Airlines UA 5921 Non-stop Canadair CRJ (CRJ) 2:07 Effective 2026-02-24 through 2026-03-04
Daily 10:55 Knoxville (TYS) 11:59 Chicago O'Hare (ORD) 2
United Airlines UA 5921 Non-stop Canadair CRJ 550 (CR5) 2:04 Effective 2026-02-12 through 2026-02-23
Thu-Sat 10:55 Knoxville (TYS) 11:59 Chicago O'Hare (ORD) 2
United Airlines UA 5921 Non-stop Canadair CRJ 550 (CR5) 2:04 Effective 2026-02-28 through 2026-03-06
Mon-Fri,Sun 10:55 Knoxville (TYS) 11:59 Chicago O'Hare (ORD) 2
United Airlines UA 5921 Non-stop Canadair CRJ 550 (CR5) 2:04 Effective 2026-03-08 through 2026-03-27
Direct Codeshare Flights:
Tue-Sun 06:45 Knoxville (TYS) 07:52 Chicago O'Hare (ORD) 2
Avianca AV 2333 Non-stop Canadair CRJ 550 (CR5) 2:07 Valid until 2026-01-04
Codeshare flight, operated by United Airlines.(UA 4553)
Fri,Sun 06:45 Knoxville (TYS) 07:48 Chicago O'Hare (ORD) 1
Avianca AV 2333 Non-stop Airbus A319 (319) 2:03 Effective 2026-01-09 through 2026-01-30
Codeshare flight, operated by United Airlines.(UA 2213)
Daily 07:00 Knoxville (TYS) 07:55 Chicago O'Hare (ORD) 1
Avianca AV 2333 Non-stop Airbus A319 (319) 1:55 Effective 2026-03-29 through 2026-05-20
Codeshare flight, operated by United Airlines.(UA 1856)
Daily 07:00 Knoxville (TYS) 07:55 Chicago O'Hare (ORD) 2
Avianca AV 2333 Non-stop Embraer EMB 175 (E7W) 1:55 Effective 2026-05-21 through 2026-08-23
Codeshare flight, operated by United Airlines.(UA 4680)
Daily 10:50 Knoxville (TYS) 11:47 Chicago O'Hare (ORD) 2
Avianca AV 2333 Non-stop Canadair CRJ 550 (CR5) 1:57 Effective 2026-08-24 through 2026-10-24
Codeshare flight, operated by United Airlines.(UA 5921)
Thu,Sat 11:07 Knoxville (TYS) 12:05 Chicago O'Hare (ORD) 2
Avianca AV 2333 Non-stop Canadair CRJ 550 (CR5) 1:58 Effective 2026-01-08 through 2026-01-31
Codeshare flight, operated by United Airlines.(UA 4529)
Tue 11:10 Knoxville (TYS) 12:03 Chicago O'Hare (ORD) 1
Avianca AV 2333 Non-stop Airbus A319 (319) 1:53 Operates only on 2026-01-06
Codeshare flight, operated by United Airlines.(UA 1155)
Wed 11:10 Knoxville (TYS) 12:05 Chicago O'Hare (ORD) 1
Avianca AV 2333 Non-stop Airbus A320 (320) 1:55 Operates only on 2026-01-07
Codeshare flight, operated by United Airlines.(UA 1155)
Tue,Wed 11:10 Knoxville (TYS) 12:05 Chicago O'Hare (ORD) 1
Avianca AV 2333 Non-stop Airbus A319 (319) 1:55 Effective 2026-01-13 through 2026-01-28
Codeshare flight, operated by United Airlines.(UA 1155)
Daily 13:53 Knoxville (TYS) 14:55 Chicago O'Hare (ORD) 2
Avianca AV 2333 Non-stop Canadair CRJ 550 (CR5) 2:02 Effective 2026-03-05 through 2026-03-28
Codeshare flight, operated by United Airlines.(UA 4514)
Daily 13:55 Knoxville (TYS) 14:59 Chicago O'Hare (ORD) 2
Avianca AV 2333 Non-stop Canadair CRJ 550 (CR5) 2:04 Effective 2026-02-12 through 2026-03-04
Codeshare flight, operated by United Airlines.(UA 4514)
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All airlines flying from Knoxville (TYS) to Chicago O'Hare (ORD).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:

Effective 2026-02-22 through 2026-03-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 2:06, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:06, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-22 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:03, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:07, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-13 through 2026-03-07
Mon
Tue
-
Wed
-
Thu
Fri
Sat
Sun
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:02, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Operates only on 2026-02-12
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Operates only on 2026-01-10
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:11, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-24 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:11, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:11, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:59, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:07, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:06, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:07, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-06 through 2026-02-02
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:58, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Operates only on 2026-02-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:01, non-stop
Embraer EMB 175 (E7W)

Direct Flights:

Effective 2026-02-04 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:58, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective from 2026-05-21
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E7W)

Direct Flights:

Effective from 2026-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Embraer EMB 175 (E7W)

Direct Flights:

Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Embraer EMB 175 (E7W)

Direct Flights:

Effective from 2026-05-21
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-02-24 through 2026-03-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:07, non-stop
Canadair CRJ (CRJ)

Direct Flights:

Effective 2026-02-12 through 2026-02-23
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-02-28 through 2026-03-06
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
Sun
-
Duration: 2:04, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-03-08 through 2026-03-27
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:04, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Valid until 2026-01-04
Mon
-
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 4553)
Duration: 2:07, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Effective 2026-01-09 through 2026-01-30
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
Codeshare flight, operated by United Airlines. (UA 2213)
Duration: 2:03, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Effective 2026-03-29 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 1856)
Duration: 1:55, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Effective 2026-05-21 through 2026-08-23
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 4680)
Duration: 1:55, non-stop
Embraer EMB 175 (E7W)

Direct Codeshare Flights:

Effective 2026-08-24 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 5921)
Duration: 1:57, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Effective 2026-01-08 through 2026-01-31
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
Sun
-
Codeshare flight, operated by United Airlines. (UA 4529)
Duration: 1:58, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by United Airlines. (UA 1155)
Duration: 1:53, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Operates only on 2026-01-07
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by United Airlines. (UA 1155)
Duration: 1:55, non-stop
Airbus A320 (320)

Direct Codeshare Flights:

Effective 2026-01-13 through 2026-01-28
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by United Airlines. (UA 1155)
Duration: 1:55, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Effective 2026-03-05 through 2026-03-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 4514)
Duration: 2:02, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Effective 2026-02-12 through 2026-03-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 4514)
Duration: 2:04, non-stop
Canadair CRJ 550 (CR5)
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  • A domestic route departing from the Knoxville airport (TYS) and arriving at Chicago O'Hare airport (ORD).
  • The flight distance is 475 miles, or 764 km.
  • The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 1:53 and 2:12.