All airlines flying from Chicago O'Hare (ORD) to Knoxville (TYS).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 18:00 Chicago O'Hare (ORD) 1 20:45 Knoxville (TYS)
United Airlines UA 1211 Non-stop Airbus A319 (319) 1:45 Effective 2026-04-30 through 2026-05-20
Daily 18:01 Chicago O'Hare (ORD) 1 20:46 Knoxville (TYS)
United Airlines UA 1211 Non-stop Airbus A319 (319) 1:45 Effective 2026-03-29 through 2026-04-29
Mon-Fri,Sun 18:06 Chicago O'Hare (ORD) 1 20:47 Knoxville (TYS)
United Airlines UA 1211 Non-stop Boeing 737-700 (73G) 1:41 Effective 2026-03-05 through 2026-03-27
Sat 18:07 Chicago O'Hare (ORD) 1 20:48 Knoxville (TYS)
United Airlines UA 1211 Non-stop Boeing 737-700 (73G) 1:41 Effective 2026-03-07 through 2026-03-28
Tue 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
United Airlines UA 1583 Non-stop Airbus A320 (320) 1:42 Operates only on 2026-01-06
Daily 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
United Airlines UA 1583 Non-stop Airbus A319 (319) 1:42 Effective 2026-01-07 through 2026-01-15
Wed,Fri 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
United Airlines UA 1583 Non-stop Airbus A320 (320) 1:42 Effective 2026-01-16 through 2026-01-21
Mon,Tue,Thu-Sun 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
United Airlines UA 1583 Non-stop Airbus A319 (319) 1:42 Effective 2026-01-17 through 2026-01-27
Daily 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
United Airlines UA 1583 Non-stop Airbus A319 (319) 1:42 Effective 2026-01-28 through 2026-02-11
Mon 19:48 Chicago O'Hare (ORD) 1 22:39 Knoxville (TYS)
United Airlines UA 1856 Non-stop Airbus A319 (319) 1:51 Operates only on 2026-01-05
Daily 18:15 Chicago O'Hare (ORD) 1 20:57 Knoxville (TYS)
United Airlines UA 2218 Non-stop Airbus A319 (319) 1:42 Effective 2026-02-12 through 2026-03-04
Wed,Sat 07:25 Chicago O'Hare (ORD) 2 10:17 Knoxville (TYS)
United Airlines UA 3607 Non-stop Embraer EMB 175 (E7W) 1:52 Valid until 2026-01-03
Daily 20:20 Chicago O'Hare (ORD) 3 23:06 Knoxville (TYS)
American Airlines AA 3920 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:46 Effective 2026-04-07 through 2026-05-20
Daily 11:40 Chicago O'Hare (ORD) 3 14:20 Knoxville (TYS)
American Airlines AA 3934 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:40 Effective from 2026-10-05
Daily 18:20 Chicago O'Hare (ORD) 2 21:05 Knoxville (TYS)
United Airlines UA 4187 Non-stop Canadair CRJ 550 (CR5) 1:45 Effective from 2026-10-25
Daily 11:40 Chicago O'Hare (ORD) 3 14:29 Knoxville (TYS)
American Airlines AA 4431 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2026-09-09 through 2026-10-04
Daily 11:41 Chicago O'Hare (ORD) 3 14:31 Knoxville (TYS)
American Airlines AA 4452 Non-stop Embraer EMB 175 (E75) 1:50 Effective 2026-08-05 through 2026-09-08
Daily 20:20 Chicago O'Hare (ORD) 3 23:16 Knoxville (TYS)
American Airlines AA 4454 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2026-05-21 through 2026-07-01
Mon,Thu,Fri,Sun 11:41 Chicago O'Hare (ORD) 3 14:31 Knoxville (TYS)
American Airlines AA 4495 Non-stop Embraer EMB 175 (E75) 1:50 Valid until 2026-01-05
Mon,Thu,Fri,Sun 14:02 Chicago O'Hare (ORD) 2 16:52 Knoxville (TYS)
United Airlines UA 4498 Non-stop Canadair CRJ 550 (CR5) 1:50 Effective 2026-02-12 through 2026-03-02
Daily 14:04 Chicago O'Hare (ORD) 2 16:49 Knoxville (TYS)
United Airlines UA 4498 Non-stop Canadair CRJ 550 (CR5) 1:45 Effective from 2026-05-21
Daily 14:35 Chicago O'Hare (ORD) 2 17:28 Knoxville (TYS)
United Airlines UA 4498 Non-stop Canadair CRJ 550 (CR5) 1:53 Effective 2026-03-29 through 2026-04-29
Daily 14:40 Chicago O'Hare (ORD) 2 17:33 Knoxville (TYS)
United Airlines UA 4498 Non-stop Canadair CRJ 550 (CR5) 1:53 Effective 2026-04-30 through 2026-05-20
Daily 14:55 Chicago O'Hare (ORD) 2 17:45 Knoxville (TYS)
United Airlines UA 4498 Non-stop Canadair CRJ 550 (CR5) 1:50 Effective 2026-03-05 through 2026-03-28
Daily 14:07 Chicago O'Hare (ORD) 2 17:00 Knoxville (TYS)
United Airlines UA 4521 Non-stop Canadair CRJ 550 (CR5) 1:53 Valid until 2026-01-05
Daily 10:35 Chicago O'Hare (ORD) 2 13:24 Knoxville (TYS)
United Airlines UA 4536 Non-stop Canadair CRJ 550 (CR5) 1:49 Effective 2026-01-06 through 2026-02-11
Daily 10:35 Chicago O'Hare (ORD) 2 13:20 Knoxville (TYS)
United Airlines UA 4536 Non-stop Canadair CRJ 550 (CR5) 1:45 Effective 2026-02-12 through 2026-03-04
Daily 10:35 Chicago O'Hare (ORD) 2 13:18 Knoxville (TYS)
United Airlines UA 4536 Non-stop Canadair CRJ 550 (CR5) 1:43 Effective 2026-03-05 through 2026-04-29
Daily 10:35 Chicago O'Hare (ORD) 2 13:19 Knoxville (TYS)
United Airlines UA 4536 Non-stop Canadair CRJ 550 (CR5) 1:44 Effective 2026-04-30 through 2026-05-20
Daily 11:40 Chicago O'Hare (ORD) 3 14:27 Knoxville (TYS)
American Airlines AA 4553 Non-stop Embraer EMB 175 (E75) 1:47 Effective 2026-07-02 through 2026-08-04
Mon,Tue,Thu-Sun 19:48 Chicago O'Hare (ORD) 2 22:39 Knoxville (TYS)
United Airlines UA 4575 Non-stop Canadair CRJ 550 (CR5) 1:51 Valid until 2026-01-04
Daily 19:50 Chicago O'Hare (ORD) 2 22:35 Knoxville (TYS)
United Airlines UA 4575 Non-stop Canadair CRJ 550 (CR5) 1:45 Effective 2026-05-21 through 2026-10-24
Daily 20:04 Chicago O'Hare (ORD) 2 22:49 Knoxville (TYS)
United Airlines UA 4575 Non-stop Canadair CRJ 550 (CR5) 1:45 Effective from 2026-10-25
Mon,Thu-Sun 07:42 Chicago O'Hare (ORD) 2 10:32 Knoxville (TYS)
United Airlines UA 4585 Non-stop Canadair CRJ 550 (CR5) 1:50 Effective 2026-01-08 through 2026-02-09
Mon,Tue,Fri,Sun 07:25 Chicago O'Hare (ORD) 2 10:15 Knoxville (TYS)
United Airlines UA 4606 Non-stop Canadair CRJ 550 (CR5) 1:50 Valid until 2026-01-05
Daily 13:11 Chicago O'Hare (ORD) 3 15:56 Knoxville (TYS)
American Airlines AA 5027 Non-stop Canadair CRJ 700 (CR7) 1:45 Valid until 2026-01-05
Daily 08:00 Chicago O'Hare (ORD) 3 10:50 Knoxville (TYS)
American Airlines AA 5040 Non-stop Canadair CRJ 700 (CR7) 1:50 Valid until 2026-01-05
Sat 19:13 Chicago O'Hare (ORD) 3 21:53 Knoxville (TYS)
American Airlines AA 5084 Non-stop Canadair CRJ 700 (CR7) 1:40 Operates only on 2026-01-24
Sat 19:14 Chicago O'Hare (ORD) 3 21:54 Knoxville (TYS)
American Airlines AA 5084 Non-stop Canadair CRJ 700 (CR7) 1:40 Effective 2026-01-31 through 2026-02-07
Daily 19:29 Chicago O'Hare (ORD) 3 22:09 Knoxville (TYS)
American Airlines AA 5084 Non-stop Canadair CRJ 700 (CR7) 1:40 Effective 2026-01-06 through 2026-01-16
Mon-Fri,Sun 19:29 Chicago O'Hare (ORD) 3 22:09 Knoxville (TYS)
American Airlines AA 5084 Non-stop Canadair CRJ 700 (CR7) 1:40 Effective 2026-01-18 through 2026-02-11
Mon,Thu,Fri 13:10 Chicago O'Hare (ORD) 3 15:52 Knoxville (TYS)
American Airlines AA 5123 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-02-12 through 2026-02-20
Mon,Thu,Fri,Sun 13:10 Chicago O'Hare (ORD) 3 15:52 Knoxville (TYS)
American Airlines AA 5123 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-02-22 through 2026-03-06
Tue,Wed 13:16 Chicago O'Hare (ORD) 3 15:58 Knoxville (TYS)
American Airlines AA 5123 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-02-17 through 2026-03-04
Daily 13:10 Chicago O'Hare (ORD) 3 15:55 Knoxville (TYS)
American Airlines AA 5168 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-09-09 through 2026-10-04
Daily 10:07 Chicago O'Hare (ORD) 3 12:46 Knoxville (TYS)
American Airlines AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:39 Effective 2026-01-06 through 2026-01-17
Daily 10:07 Chicago O'Hare (ORD) 3 12:46 Knoxville (TYS)
American Airlines AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:39 Effective 2026-01-19 through 2026-02-11
Daily 18:30 Chicago O'Hare (ORD) 3 21:15 Knoxville (TYS)
American Airlines AA 5195 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-09-09 through 2026-10-04
Daily 18:30 Chicago O'Hare (ORD) 3 21:04 Knoxville (TYS)
American Airlines AA 5196 Non-stop Canadair CRJ 700 (CR7) 1:34 Effective from 2026-10-05
Daily 09:40 Chicago O'Hare (ORD) 3 12:28 Knoxville (TYS)
American Airlines AA 5197 Non-stop Canadair CRJ 700 (CR7) 1:48 Effective from 2026-10-05
1 2 3 4 5 6 7   next


All airlines flying from Chicago O'Hare (ORD) to Knoxville (TYS).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:

Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Airbus A319 (319)

Direct Flights:

Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Airbus A319 (319)

Direct Flights:

Effective 2026-03-05 through 2026-03-27
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:41, non-stop
Boeing 737-700 (73G)

Direct Flights:

Effective 2026-03-07 through 2026-03-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:41, non-stop
Boeing 737-700 (73G)

Direct Flights:

Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:42, non-stop
Airbus A320 (320)

Direct Flights:

Effective 2026-01-07 through 2026-01-15
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Airbus A319 (319)

Direct Flights:

Effective 2026-01-16 through 2026-01-21
Mon
-
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:42, non-stop
Airbus A320 (320)

Direct Flights:

Effective 2026-01-17 through 2026-01-27
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Airbus A319 (319)

Direct Flights:

Effective 2026-01-28 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Airbus A319 (319)

Direct Flights:

Operates only on 2026-01-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:51, non-stop
Airbus A319 (319)

Direct Flights:

Effective 2026-02-12 through 2026-03-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Airbus A319 (319)

Direct Flights:

Valid until 2026-01-03
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:52, non-stop
Embraer EMB 175 (E7W)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:46, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:40, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective from 2026-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:49, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:50, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-02-12 through 2026-03-02
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:50, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective from 2026-05-21
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-03-05 through 2026-03-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:49, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-02-12 through 2026-03-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-03-05 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Valid until 2026-01-04
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 1:51, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-05-21 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective from 2026-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-01-08 through 2026-02-09
Mon
Tue
-
Wed
-
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
-
Fri
Sat
-
Sun
Duration: 1:50, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Operates only on 2026-01-24
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:40, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-31 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:40, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-06 through 2026-01-16
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:40, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-18 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:40, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-12 through 2026-02-20
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-22 through 2026-03-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-06 through 2026-01-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-19 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:34, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:48, non-stop
Canadair CRJ 700 (CR7)
Page 1 / 7        next
  • A domestic route departing from the Chicago O'Hare airport (ORD) and arriving at Knoxville airport (TYS).
  • The flight distance is 475 miles, or 764 km.
  • The timezone of the departure airport is UTC-6 , and the timezone of the arrival airport is UTC-5 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 1:34 and 1:56.