All airlines flying from New York LaGuardia (LGA) to Des Moines (DSM).

FLIGHT SCHEDULE
Direct Flights:
Daily 16:45 New York LaGuardia (LGA) B 18:44 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 2:59 Effective 2026-04-07 through 2026-05-20
Daily 17:15 New York LaGuardia (LGA) B 19:18 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 3:03 Effective 2026-05-21 through 2026-07-01
Daily 17:15 New York LaGuardia (LGA) B 19:23 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 3:08 Effective 2026-07-02 through 2026-08-04
Daily 17:15 New York LaGuardia (LGA) B 19:19 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 3:04 Effective 2026-08-05 through 2026-09-08
Mon-Thu,Sun 17:40 New York LaGuardia (LGA) B 19:58 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 3:18 Effective 2026-01-06 through 2026-02-11
Mon-Thu,Sun 17:40 New York LaGuardia (LGA) B 20:06 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 3:26 Effective 2026-02-12 through 2026-03-05
Mon-Thu,Sun 17:40 New York LaGuardia (LGA) B 19:57 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 3:17 Effective 2026-03-08 through 2026-04-06
Daily 20:15 New York LaGuardia (LGA) B 22:27 Des Moines (DSM) American Airlines AA 4395 Non-stop Embraer EMB 175 (E75) 3:12 Effective 2026-09-09 through 2026-10-04
Daily 13:55 New York LaGuardia (LGA) C 16:04 Des Moines (DSM) Delta Air Lines DL 4736 Non-stop Canadair CRJ 900 (CR9) 3:09 Effective from 2026-10-25
Sat 09:20 New York LaGuardia (LGA) C 11:40 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:20 Operates only on 2026-02-07
Sat 09:25 New York LaGuardia (LGA) C 11:45 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:20 Effective 2026-01-10 through 2026-01-31
Sat 09:25 New York LaGuardia (LGA) C 11:43 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:18 Effective 2026-02-14 through 2026-03-07
Sat 09:30 New York LaGuardia (LGA) C 11:38 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:08 Effective 2026-03-14 through 2026-04-11
Wed,Thu 13:45 New York LaGuardia (LGA) C 15:50 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:05 Valid until 2026-01-01
Mon-Fri,Sun 17:15 New York LaGuardia (LGA) C 19:34 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:19 Effective 2026-01-05 through 2026-02-11
Mon-Fri,Sun 17:15 New York LaGuardia (LGA) C 19:33 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:18 Effective 2026-02-12 through 2026-02-25
Mon-Fri,Sun 17:15 New York LaGuardia (LGA) C 19:33 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:18 Effective 2026-02-27 through 2026-03-06
Mon-Fri,Sun 17:15 New York LaGuardia (LGA) C 19:27 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:12 Effective 2026-03-08 through 2026-04-12
Thu 17:18 New York LaGuardia (LGA) C 19:36 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:18 Operates only on 2026-02-26
Mon,Tue,Fri-Sun 17:20 New York LaGuardia (LGA) C 19:29 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:09 Valid until 2026-01-04
Daily 17:45 New York LaGuardia (LGA) C 19:55 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:10 Effective 2026-04-13 through 2026-10-05
Daily 17:45 New York LaGuardia (LGA) C 20:00 Des Moines (DSM) Delta Air Lines DL 4904 Non-stop Canadair CRJ 900 (CR9) 3:15 Effective from 2026-10-06

A domestic route departing from the New York LaGuardia airport (LGA) and arriving at Des Moines airport (DSM).
The flight distance is 1027 miles, or 1653 km.
The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
For direct flights, the flight time varies between 2:59 and 3:26.

Return (DSM-LGA) flights

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All airlines flying from New York LaGuardia (LGA) to Des Moines (DSM).

FLIGHT SCHEDULE

Direct Flights:

American Airlines AA4395

16:45

New York LaGuardia (LGA) B

18:44

Des Moines (DSM)

Effective 2026-04-07 through 2026-05-20

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:59, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4395

17:15

New York LaGuardia (LGA) B

19:18

Des Moines (DSM)

Effective 2026-05-21 through 2026-07-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:03, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4395

17:15

New York LaGuardia (LGA) B

19:23

Des Moines (DSM)

Effective 2026-07-02 through 2026-08-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:08, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4395

17:15

New York LaGuardia (LGA) B

19:19

Des Moines (DSM)

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:04, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4395

17:40

New York LaGuardia (LGA) B

19:58

Des Moines (DSM)

Effective 2026-01-06 through 2026-02-11

Mon

Tue

Wed

Thu

Fri
-

Sat
-

Sun

Duration: 3:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4395

17:40

New York LaGuardia (LGA) B

20:06

Des Moines (DSM)

Effective 2026-02-12 through 2026-03-05

Mon

Tue

Wed

Thu

Fri
-

Sat
-

Sun

Duration: 3:26, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4395

17:40

New York LaGuardia (LGA) B

19:57

Des Moines (DSM)

Effective 2026-03-08 through 2026-04-06

Mon

Tue

Wed

Thu

Fri
-

Sat
-

Sun

Duration: 3:17, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4395

20:15

New York LaGuardia (LGA) B

22:27

Des Moines (DSM)

Effective 2026-09-09 through 2026-10-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:12, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL4736

13:55

New York LaGuardia (LGA) C

16:04

Des Moines (DSM)

Effective from 2026-10-25

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:09, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

09:20

New York LaGuardia (LGA) C

11:40

Des Moines (DSM)

Operates only on 2026-02-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 3:20, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

09:25

New York LaGuardia (LGA) C

11:45

Des Moines (DSM)

Effective 2026-01-10 through 2026-01-31

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 3:20, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

09:25

New York LaGuardia (LGA) C

11:43

Des Moines (DSM)

Effective 2026-02-14 through 2026-03-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 3:18, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

09:30

New York LaGuardia (LGA) C

11:38

Des Moines (DSM)

Effective 2026-03-14 through 2026-04-11

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 3:08, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

13:45

New York LaGuardia (LGA) C

15:50

Des Moines (DSM)

Valid until 2026-01-01

Mon
-

Tue
-

Wed

Thu

Fri
-

Sat
-

Sun
-

Duration: 3:05, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:15

New York LaGuardia (LGA) C

19:34

Des Moines (DSM)

Effective 2026-01-05 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 3:19, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:15

New York LaGuardia (LGA) C

19:33

Des Moines (DSM)

Effective 2026-02-12 through 2026-02-25

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 3:18, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:15

New York LaGuardia (LGA) C

19:33

Des Moines (DSM)

Effective 2026-02-27 through 2026-03-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 3:18, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:15

New York LaGuardia (LGA) C

19:27

Des Moines (DSM)

Effective 2026-03-08 through 2026-04-12

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 3:12, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:18

New York LaGuardia (LGA) C

19:36

Des Moines (DSM)

Operates only on 2026-02-26

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Duration: 3:18, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:20

New York LaGuardia (LGA) C

19:29

Des Moines (DSM)

Valid until 2026-01-04

Mon

Tue

Wed
-

Thu
-

Fri

Sat

Sun

Duration: 3:09, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:45

New York LaGuardia (LGA) C

19:55

Des Moines (DSM)

Effective 2026-04-13 through 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:10, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4904

17:45

New York LaGuardia (LGA) C

20:00

Des Moines (DSM)

Effective from 2026-10-06

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:15, non-stop
Canadair CRJ 900 (CR9)

A domestic route departing from the New York LaGuardia airport (LGA) and arriving at Des Moines airport (DSM).
The flight distance is 1027 miles, or 1653 km.
The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
For direct flights, the flight time varies between 2:59 and 3:26.

Return (DSM-LGA) flights

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