All airlines flying from Des Moines (DSM) to New York LaGuardia (LGA).

FLIGHT SCHEDULE
Direct Flights:
Mon-Fri 07:01 Des Moines (DSM) 10:51 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:50 Effective 2026-02-12 through 2026-03-06
Daily 07:06 Des Moines (DSM) 10:45 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:39 Effective from 2026-10-05
Daily 07:07 Des Moines (DSM) 10:49 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:42 Effective 2026-04-07 through 2026-05-20
Daily 07:13 Des Moines (DSM) 10:59 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:46 Effective 2026-07-02 through 2026-08-04
Daily 07:15 Des Moines (DSM) 11:00 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:45 Effective 2026-08-05 through 2026-09-08
Daily 07:19 Des Moines (DSM) 10:59 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:40 Effective 2026-05-21 through 2026-07-01
Mon-Fri 07:43 Des Moines (DSM) 11:30 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:47 Effective 2026-01-07 through 2026-02-11
Mon-Fri 07:45 Des Moines (DSM) 11:29 New York LaGuardia (LGA) B American Airlines AA 4795 Non-stop Embraer EMB 175 (E75) 2:44 Effective 2026-03-09 through 2026-04-06
Daily 07:25 Des Moines (DSM) 11:10 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:45 Effective from 2026-04-13
Daily 07:30 Des Moines (DSM) 11:13 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:43 Valid until 2026-01-04
Mon-Fri 07:30 Des Moines (DSM) 11:08 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:38 Effective 2026-03-09 through 2026-04-10
Mon-Fri 07:34 Des Moines (DSM) 11:14 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:40 Effective 2026-01-05 through 2026-03-06
Sun 09:15 Des Moines (DSM) 12:53 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:38 Effective 2026-03-08 through 2026-04-12
Sun 09:45 Des Moines (DSM) 13:28 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:43 Effective 2026-01-25 through 2026-02-08
Sun 10:14 Des Moines (DSM) 13:57 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:43 Effective 2026-01-11 through 2026-01-18
Sat 10:15 Des Moines (DSM) 13:58 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:43 Effective 2026-01-24 through 2026-01-31
Sat 10:15 Des Moines (DSM) 13:53 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:38 Effective 2026-03-14 through 2026-04-11
Sat 10:16 Des Moines (DSM) 13:59 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:43 Effective 2026-01-10 through 2026-01-17
Sat 10:20 Des Moines (DSM) 14:03 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:43 Operates only on 2026-02-07
Sat,Sun 10:56 Des Moines (DSM) 14:28 New York LaGuardia (LGA) C Delta Air Lines DL 4945 Non-stop Canadair CRJ 900 (CR9) 2:32 Effective 2026-02-14 through 2026-03-07
Daily 17:30 Des Moines (DSM) 21:11 New York LaGuardia (LGA) C Delta Air Lines DL 5456 Non-stop Canadair CRJ 900 (CR9) 2:41 Effective from 2026-10-25

A domestic route departing from the Des Moines airport (DSM) and arriving at New York LaGuardia airport (LGA).
The flight distance is 1027 miles, or 1653 km.
The timezone of the departure airport is UTC-6 , and the timezone of the arrival airport is UTC-5 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
For direct flights, the flight time varies between 2:32 and 2:50.

Return (LGA-DSM) flights

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All airlines flying from Des Moines (DSM) to New York LaGuardia (LGA).

FLIGHT SCHEDULE

Direct Flights:

American Airlines AA4795

07:01

Des Moines (DSM)

10:51

New York LaGuardia (LGA) B

Effective 2026-02-12 through 2026-03-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:50, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4795

07:06

Des Moines (DSM)

10:45

New York LaGuardia (LGA) B

Effective from 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:39, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4795

07:07

Des Moines (DSM)

10:49

New York LaGuardia (LGA) B

Effective 2026-04-07 through 2026-05-20

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:42, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4795

07:13

Des Moines (DSM)

10:59

New York LaGuardia (LGA) B

Effective 2026-07-02 through 2026-08-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:46, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4795

07:15

Des Moines (DSM)

11:00

New York LaGuardia (LGA) B

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:45, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4795

07:19

Des Moines (DSM)

10:59

New York LaGuardia (LGA) B

Effective 2026-05-21 through 2026-07-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:40, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4795

07:43

Des Moines (DSM)

11:30

New York LaGuardia (LGA) B

Effective 2026-01-07 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:47, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4795

07:45

Des Moines (DSM)

11:29

New York LaGuardia (LGA) B

Effective 2026-03-09 through 2026-04-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:44, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL4945

07:25

Des Moines (DSM)

11:10

New York LaGuardia (LGA) C

Effective from 2026-04-13

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:45, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

07:30

Des Moines (DSM)

11:13

New York LaGuardia (LGA) C

Valid until 2026-01-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:43, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

07:30

Des Moines (DSM)

11:08

New York LaGuardia (LGA) C

Effective 2026-03-09 through 2026-04-10

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:38, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

07:34

Des Moines (DSM)

11:14

New York LaGuardia (LGA) C

Effective 2026-01-05 through 2026-03-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:40, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

09:15

Des Moines (DSM)

12:53

New York LaGuardia (LGA) C

Effective 2026-03-08 through 2026-04-12

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:38, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

09:45

Des Moines (DSM)

13:28

New York LaGuardia (LGA) C

Effective 2026-01-25 through 2026-02-08

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:43, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

10:14

Des Moines (DSM)

13:57

New York LaGuardia (LGA) C

Effective 2026-01-11 through 2026-01-18

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:43, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

10:15

Des Moines (DSM)

13:58

New York LaGuardia (LGA) C

Effective 2026-01-24 through 2026-01-31

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:43, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

10:15

Des Moines (DSM)

13:53

New York LaGuardia (LGA) C

Effective 2026-03-14 through 2026-04-11

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:38, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

10:16

Des Moines (DSM)

13:59

New York LaGuardia (LGA) C

Effective 2026-01-10 through 2026-01-17

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:43, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

10:20

Des Moines (DSM)

14:03

New York LaGuardia (LGA) C

Operates only on 2026-02-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:43, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL4945

10:56

Des Moines (DSM)

14:28

New York LaGuardia (LGA) C

Effective 2026-02-14 through 2026-03-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun

Duration: 2:32, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

Delta Air Lines DL5456

17:30

Des Moines (DSM)

21:11

New York LaGuardia (LGA) C

Effective from 2026-10-25

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:41, non-stop
Canadair CRJ 900 (CR9)

A domestic route departing from the Des Moines airport (DSM) and arriving at New York LaGuardia airport (LGA).
The flight distance is 1027 miles, or 1653 km.
The timezone of the departure airport is UTC-6 , and the timezone of the arrival airport is UTC-5 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
For direct flights, the flight time varies between 2:32 and 2:50.

Return (LGA-DSM) flights

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