American Airlines flights from Des Moines (DSM) to Chicago O'Hare (ORD).

FLIGHT SCHEDULE
Direct Flights:
Daily 05:00 Des Moines (DSM) 06:05 Chicago O'Hare (ORD) 3 American Airlines AA 449 Non-stop Airbus A319 (319) 1:05 Effective 2026-05-21 through 2026-07-01
Daily 05:58 Des Moines (DSM) 07:25 Chicago O'Hare (ORD) 3 American Airlines AA 449 Non-stop Airbus A319 (319) 1:27 Effective 2026-07-02 through 2026-08-04
Daily 07:34 Des Moines (DSM) 09:05 Chicago O'Hare (ORD) 3 American Airlines AA 2309 Non-stop Airbus A319 (319) 1:31 Effective 2026-09-09 through 2026-10-04
Daily 07:30 Des Moines (DSM) 09:05 Chicago O'Hare (ORD) 3 American Airlines AA 2462 Non-stop Boeing 737-800 (738) 1:35 Effective from 2026-10-05
Daily 13:22 Des Moines (DSM) 14:53 Chicago O'Hare (ORD) 3 American Airlines AA 3413 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:31 Effective 2026-08-05 through 2026-09-08
Daily 13:40 Des Moines (DSM) 15:15 Chicago O'Hare (ORD) 3 American Airlines AA 3444 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:35 Effective 2026-03-08 through 2026-04-06
Mon,Tue,Thu-Sun 11:42 Des Moines (DSM) 13:18 Chicago O'Hare (ORD) 3 American Airlines AA 3469 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2026-01-06 through 2026-01-17
Wed 11:42 Des Moines (DSM) 13:18 Chicago O'Hare (ORD) 3 American Airlines AA 3469 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:36 Effective 2026-01-07 through 2026-01-14
Sun 11:42 Des Moines (DSM) 13:18 Chicago O'Hare (ORD) 3 American Airlines AA 3469 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:36 Operates only on 2026-01-18
Mon,Tue,Thu-Sun 11:42 Des Moines (DSM) 13:18 Chicago O'Hare (ORD) 3 American Airlines AA 3469 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2026-01-19 through 2026-02-06
Wed 11:42 Des Moines (DSM) 13:18 Chicago O'Hare (ORD) 3 American Airlines AA 3469 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:36 Effective 2026-01-21 through 2026-02-11
Mon,Tue,Sun 11:42 Des Moines (DSM) 13:18 Chicago O'Hare (ORD) 3 American Airlines AA 3469 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2026-02-08 through 2026-02-10
Sat 18:24 Des Moines (DSM) 20:00 Chicago O'Hare (ORD) 3 American Airlines AA 3653 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:36 Operates only on 2026-02-14
Sat 19:00 Des Moines (DSM) 20:36 Chicago O'Hare (ORD) 3 American Airlines AA 3653 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:36 Effective 2026-02-21 through 2026-03-07
Sat 19:00 Des Moines (DSM) 20:41 Chicago O'Hare (ORD) 3 American Airlines AA 3653 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:41 Effective 2026-03-14 through 2026-04-04
Mon,Wed-Sun 13:25 Des Moines (DSM) 15:04 Chicago O'Hare (ORD) 3 American Airlines AA 3703 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:39 Valid until 2026-01-05
Mon-Fri 06:40 Des Moines (DSM) 08:20 Chicago O'Hare (ORD) 3 American Airlines AA 3857 Non-stop Embraer EMB 175 (E75) 1:40 Valid until 2026-01-05
Daily 07:29 Des Moines (DSM) 09:00 Chicago O'Hare (ORD) 3 American Airlines AA 3942 Non-stop Embraer EMB 175 (E75) 1:31 Effective 2026-08-05 through 2026-09-08
Mon,Tue,Thu,Fri,Sun 15:27 Des Moines (DSM) 17:06 Chicago O'Hare (ORD) 3 American Airlines AA 4103 Non-stop Embraer EMB 175 (E75) 1:39 Valid until 2026-01-05
Tue 07:00 Des Moines (DSM) 08:44 Chicago O'Hare (ORD) 3 American Airlines AA 4136 Non-stop Embraer EMB 175 (E75) 1:44 Operates only on 2026-01-06
Daily 07:00 Des Moines (DSM) 08:44 Chicago O'Hare (ORD) 3 American Airlines AA 4136 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:44 Effective 2026-01-07 through 2026-01-17
Daily 07:00 Des Moines (DSM) 08:44 Chicago O'Hare (ORD) 3 American Airlines AA 4136 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:44 Effective 2026-01-19 through 2026-02-11
Sun 13:55 Des Moines (DSM) 15:31 Chicago O'Hare (ORD) 3 American Airlines AA 4136 Non-stop Embraer EMB 175 (E75) 1:36 Operates only on 2026-01-18
Daily 05:00 Des Moines (DSM) 06:30 Chicago O'Hare (ORD) 3 American Airlines AA 4383 Non-stop Embraer EMB 175 (E75) 1:30 Effective 2026-08-05 through 2026-09-08
Daily 05:00 Des Moines (DSM) 06:10 Chicago O'Hare (ORD) 3 American Airlines AA 4390 Non-stop Embraer EMB 175 (E75) 1:10 Effective 2026-09-09 through 2026-10-04
Daily 12:49 Des Moines (DSM) 14:20 Chicago O'Hare (ORD) 3 American Airlines AA 4431 Non-stop Embraer EMB 175 (E75) 1:31 Effective 2026-04-07 through 2026-05-20
Daily 18:19 Des Moines (DSM) 19:50 Chicago O'Hare (ORD) 3 American Airlines AA 4432 Non-stop Embraer EMB 175 (E75) 1:31 Effective 2026-04-07 through 2026-05-20
Daily 05:00 Des Moines (DSM) 06:10 Chicago O'Hare (ORD) 3 American Airlines AA 4467 Non-stop Embraer EMB 175 (E75) 1:10 Effective from 2026-10-05
Daily 07:24 Des Moines (DSM) 09:10 Chicago O'Hare (ORD) 3 American Airlines AA 4519 Non-stop Embraer EMB 175 (E75) 1:46 Effective 2026-05-21 through 2026-07-01
Daily 07:32 Des Moines (DSM) 09:10 Chicago O'Hare (ORD) 3 American Airlines AA 4519 Non-stop Embraer EMB 175 (E75) 1:38 Effective 2026-07-02 through 2026-08-04
Sun 18:27 Des Moines (DSM) 20:16 Chicago O'Hare (ORD) 3 American Airlines AA 4753 Non-stop Embraer EMB 175 (E75) 1:49 Operates only on 2026-02-15
Sat 06:00 Des Moines (DSM) 07:43 Chicago O'Hare (ORD) 3 American Airlines AA 4778 Non-stop Embraer EMB 175 (E75) 1:43 Effective 2026-03-14 through 2026-04-04
Tue,Wed,Sat,Sun 06:26 Des Moines (DSM) 08:15 Chicago O'Hare (ORD) 3 American Airlines AA 4778 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2026-02-14 through 2026-02-21
Tue,Wed,Sat 06:26 Des Moines (DSM) 08:15 Chicago O'Hare (ORD) 3 American Airlines AA 4778 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2026-02-24 through 2026-03-07
Sat,Sun 06:30 Des Moines (DSM) 08:10 Chicago O'Hare (ORD) 3 American Airlines AA 4778 Non-stop Embraer EMB 175 (E75) 1:40 Effective 2026-01-03 through 2026-01-04
Mon-Fri,Sun 06:37 Des Moines (DSM) 08:20 Chicago O'Hare (ORD) 3 American Airlines AA 4778 Non-stop Embraer EMB 175 (E75) 1:43 Effective 2026-03-08 through 2026-04-06
Mon,Thu,Fri 06:46 Des Moines (DSM) 08:35 Chicago O'Hare (ORD) 3 American Airlines AA 4778 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2026-02-13 through 2026-02-20
Mon,Thu,Fri,Sun 06:46 Des Moines (DSM) 08:35 Chicago O'Hare (ORD) 3 American Airlines AA 4778 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2026-02-22 through 2026-03-06
Daily 10:09 Des Moines (DSM) 11:43 Chicago O'Hare (ORD) 3 American Airlines AA 4899 Non-stop Canadair CRJ 700 (CR7) 1:34 Effective 2026-02-12 through 2026-03-07
Daily 14:37 Des Moines (DSM) 16:10 Chicago O'Hare (ORD) 3 American Airlines AA 4903 Non-stop Canadair CRJ 700 (CR7) 1:33 Effective from 2026-10-05
Daily 18:07 Des Moines (DSM) 19:50 Chicago O'Hare (ORD) 3 American Airlines AA 4904 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective from 2026-10-05
Mon-Thu 19:00 Des Moines (DSM) 20:43 Chicago O'Hare (ORD) 3 American Airlines AA 4923 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-03-09 through 2026-04-06
Fri,Sun 19:44 Des Moines (DSM) 21:25 Chicago O'Hare (ORD) 3 American Airlines AA 4923 Non-stop Canadair CRJ 700 (CR7) 1:41 Effective 2026-03-08 through 2026-04-05
Daily 18:15 Des Moines (DSM) 19:50 Chicago O'Hare (ORD) 3 American Airlines AA 4928 Non-stop Canadair CRJ 700 (CR7) 1:35 Effective 2026-09-09 through 2026-10-04
Daily 05:58 Des Moines (DSM) 07:30 Chicago O'Hare (ORD) 3 American Airlines AA 4931 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-04-07 through 2026-05-20
Daily 09:38 Des Moines (DSM) 11:10 Chicago O'Hare (ORD) 3 American Airlines AA 4932 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-09-09 through 2026-10-04
Daily 14:36 Des Moines (DSM) 16:10 Chicago O'Hare (ORD) 3 American Airlines AA 4933 Non-stop Canadair CRJ 700 (CR7) 1:34 Effective 2026-09-09 through 2026-10-04
Daily 09:00 Des Moines (DSM) 10:29 Chicago O'Hare (ORD) 3 American Airlines AA 4955 Non-stop Canadair CRJ 700 (CR7) 1:29 Effective 2026-08-05 through 2026-09-08
Daily 15:41 Des Moines (DSM) 17:11 Chicago O'Hare (ORD) 3 American Airlines AA 4965 Non-stop Canadair CRJ 700 (CR7) 1:30 Effective 2026-08-05 through 2026-09-08
Daily 09:38 Des Moines (DSM) 11:10 Chicago O'Hare (ORD) 3 American Airlines AA 4969 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-05-21 through 2026-07-01

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A domestic route departing from the Des Moines airport (DSM) and arriving at Chicago O'Hare airport (ORD).
The flight distance is 298 miles, or 479 km.
The timezone of both the departure and the arrival airports is UTC-6 . Current time at both airports is (loading...).
For direct flights, the flight time varies between 1:05 and 1:51.

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American Airlines flights from Des Moines (DSM) to Chicago O'Hare (ORD).

FLIGHT SCHEDULE

Direct Flights:

American Airlines AA449

05:00

Des Moines (DSM)

06:05

Chicago O'Hare (ORD) 3

Effective 2026-05-21 through 2026-07-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:05, non-stop
Airbus A319 (319)

Direct Flights:

American Airlines AA449

05:58

Des Moines (DSM)

07:25

Chicago O'Hare (ORD) 3

Effective 2026-07-02 through 2026-08-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:27, non-stop
Airbus A319 (319)

Direct Flights:

American Airlines AA2309

07:34

Des Moines (DSM)

09:05

Chicago O'Hare (ORD) 3

Effective 2026-09-09 through 2026-10-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:31, non-stop
Airbus A319 (319)

Direct Flights:

American Airlines AA2462

07:30

Des Moines (DSM)

09:05

Chicago O'Hare (ORD) 3

Effective from 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:35, non-stop
Boeing 737-800 (738)

Direct Flights:

American Airlines AA3413

13:22

Des Moines (DSM)

14:53

Chicago O'Hare (ORD) 3

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:31, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3444

13:40

Des Moines (DSM)

15:15

Chicago O'Hare (ORD) 3

Effective 2026-03-08 through 2026-04-06

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:35, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3469

11:42

Des Moines (DSM)

13:18

Chicago O'Hare (ORD) 3

Effective 2026-01-06 through 2026-01-17

Mon

Tue

Wed
-

Thu

Fri

Sat

Sun

Duration: 1:36, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA3469

11:42

Des Moines (DSM)

13:18

Chicago O'Hare (ORD) 3

Effective 2026-01-07 through 2026-01-14

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:36, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3469

11:42

Des Moines (DSM)

13:18

Chicago O'Hare (ORD) 3

Operates only on 2026-01-18

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:36, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3469

11:42

Des Moines (DSM)

13:18

Chicago O'Hare (ORD) 3

Effective 2026-01-19 through 2026-02-06

Mon

Tue

Wed
-

Thu

Fri

Sat

Sun

Duration: 1:36, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA3469

11:42

Des Moines (DSM)

13:18

Chicago O'Hare (ORD) 3

Effective 2026-01-21 through 2026-02-11

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:36, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3469

11:42

Des Moines (DSM)

13:18

Chicago O'Hare (ORD) 3

Effective 2026-02-08 through 2026-02-10

Mon

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:36, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA3653

18:24

Des Moines (DSM)

20:00

Chicago O'Hare (ORD) 3

Operates only on 2026-02-14

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:36, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3653

19:00

Des Moines (DSM)

20:36

Chicago O'Hare (ORD) 3

Effective 2026-02-21 through 2026-03-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:36, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3653

19:00

Des Moines (DSM)

20:41

Chicago O'Hare (ORD) 3

Effective 2026-03-14 through 2026-04-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:41, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3703

13:25

Des Moines (DSM)

15:04

Chicago O'Hare (ORD) 3

Valid until 2026-01-05

Mon

Tue
-

Wed

Thu

Fri

Sat

Sun

Duration: 1:39, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA3857

06:40

Des Moines (DSM)

08:20

Chicago O'Hare (ORD) 3

Valid until 2026-01-05

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 1:40, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA3942

07:29

Des Moines (DSM)

09:00

Chicago O'Hare (ORD) 3

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:31, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4103

15:27

Des Moines (DSM)

17:06

Chicago O'Hare (ORD) 3

Valid until 2026-01-05

Mon

Tue

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:39, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4136

07:00

Des Moines (DSM)

08:44

Chicago O'Hare (ORD) 3

Operates only on 2026-01-06

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:44, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4136

07:00

Des Moines (DSM)

08:44

Chicago O'Hare (ORD) 3

Effective 2026-01-07 through 2026-01-17

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:44, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4136

07:00

Des Moines (DSM)

08:44

Chicago O'Hare (ORD) 3

Effective 2026-01-19 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:44, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4136

13:55

Des Moines (DSM)

15:31

Chicago O'Hare (ORD) 3

Operates only on 2026-01-18

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:36, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4383

05:00

Des Moines (DSM)

06:30

Chicago O'Hare (ORD) 3

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:30, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390

05:00

Des Moines (DSM)

06:10

Chicago O'Hare (ORD) 3

Effective 2026-09-09 through 2026-10-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:10, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4431

12:49

Des Moines (DSM)

14:20

Chicago O'Hare (ORD) 3

Effective 2026-04-07 through 2026-05-20

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:31, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4432

18:19

Des Moines (DSM)

19:50

Chicago O'Hare (ORD) 3

Effective 2026-04-07 through 2026-05-20

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:31, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4467

05:00

Des Moines (DSM)

06:10

Chicago O'Hare (ORD) 3

Effective from 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:10, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4519

07:24

Des Moines (DSM)

09:10

Chicago O'Hare (ORD) 3

Effective 2026-05-21 through 2026-07-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:46, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4519

07:32

Des Moines (DSM)

09:10

Chicago O'Hare (ORD) 3

Effective 2026-07-02 through 2026-08-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:38, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4753

18:27

Des Moines (DSM)

20:16

Chicago O'Hare (ORD) 3

Operates only on 2026-02-15

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:49, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4778

06:00

Des Moines (DSM)

07:43

Chicago O'Hare (ORD) 3

Effective 2026-03-14 through 2026-04-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:43, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4778

06:26

Des Moines (DSM)

08:15

Chicago O'Hare (ORD) 3

Effective 2026-02-14 through 2026-02-21

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat

Sun

Duration: 1:49, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4778

06:26

Des Moines (DSM)

08:15

Chicago O'Hare (ORD) 3

Effective 2026-02-24 through 2026-03-07

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:49, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4778

06:30

Des Moines (DSM)

08:10

Chicago O'Hare (ORD) 3

Effective 2026-01-03 through 2026-01-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun

Duration: 1:40, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4778

06:37

Des Moines (DSM)

08:20

Chicago O'Hare (ORD) 3

Effective 2026-03-08 through 2026-04-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 1:43, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4778

06:46

Des Moines (DSM)

08:35

Chicago O'Hare (ORD) 3

Effective 2026-02-13 through 2026-02-20

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun
-

Duration: 1:49, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4778

06:46

Des Moines (DSM)

08:35

Chicago O'Hare (ORD) 3

Effective 2026-02-22 through 2026-03-06

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:49, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4899

10:09

Des Moines (DSM)

11:43

Chicago O'Hare (ORD) 3

Effective 2026-02-12 through 2026-03-07

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:34, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4903

14:37

Des Moines (DSM)

16:10

Chicago O'Hare (ORD) 3

Effective from 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:33, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4904

18:07

Des Moines (DSM)

19:50

Chicago O'Hare (ORD) 3

Effective from 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4923

19:00

Des Moines (DSM)

20:43

Chicago O'Hare (ORD) 3

Effective 2026-03-09 through 2026-04-06

Mon

Tue

Wed

Thu

Fri
-

Sat
-

Sun
-

Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4923

19:44

Des Moines (DSM)

21:25

Chicago O'Hare (ORD) 3

Effective 2026-03-08 through 2026-04-05

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun

Duration: 1:41, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4928

18:15

Des Moines (DSM)

19:50

Chicago O'Hare (ORD) 3

Effective 2026-09-09 through 2026-10-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:35, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4931

05:58

Des Moines (DSM)

07:30

Chicago O'Hare (ORD) 3

Effective 2026-04-07 through 2026-05-20

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4932

09:38

Des Moines (DSM)

11:10

Chicago O'Hare (ORD) 3

Effective 2026-09-09 through 2026-10-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4933

14:36

Des Moines (DSM)

16:10

Chicago O'Hare (ORD) 3

Effective 2026-09-09 through 2026-10-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:34, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4955

09:00

Des Moines (DSM)

10:29

Chicago O'Hare (ORD) 3

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:29, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4965

15:41

Des Moines (DSM)

17:11

Chicago O'Hare (ORD) 3

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:30, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA4969

09:38

Des Moines (DSM)

11:10

Chicago O'Hare (ORD) 3

Effective 2026-05-21 through 2026-07-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)

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A domestic route departing from the Des Moines airport (DSM) and arriving at Chicago O'Hare airport (ORD).
The flight distance is 298 miles, or 479 km.
The timezone of both the departure and the arrival airports is UTC-6 . Current time at both airports is (loading...).
For direct flights, the flight time varies between 1:05 and 1:51.

All DSM-ORD flights

All American Airlines flights

Return (ORD-DSM) flights

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