American Airlines flight AA 4778: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 05:49 Des Moines (DSM) 07:30 Chicago O'Hare (ORD) 3
AA 4778 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-12-18 through 2026-01-05
Daily 05:59 Des Moines (DSM) 07:30 Chicago O'Hare (ORD) 3
AA 4778 Non-stop Embraer EMB 175 (E75) 1:31 Effective from 2026-02-12
Daily 06:49 Chicago O'Hare (ORD) 3 08:28 Kansas City (MCI)
AA 4778 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-05-05 through 2025-05-24
Daily 06:49 Chicago O'Hare (ORD) 3 08:28 Kansas City (MCI)
AA 4778 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-05-26 through 2025-06-04
Daily 09:02 Kansas City (MCI) 10:43 Chicago O'Hare (ORD) 3
AA 4778 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-05-05 through 2025-05-24
Daily 09:02 Kansas City (MCI) 10:43 Chicago O'Hare (ORD) 3
AA 4778 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-05-26 through 2025-06-04
Mon-Fri,Sun 14:54 Ronald Reagan Washington (DCA) 2 16:12 New York LaGuardia (LGA) B
AA 4778 Non-stop Embraer EMB 175 (E75) 1:18 Valid until 2025-05-04
Tue,Wed 19:14 Boston Logan (BOS) B 21:20 Chicago O'Hare (ORD) 3
AA 4778 Non-stop Embraer EMB 175 (E75) 3:06 Effective 2025-07-08 through 2025-08-05
Tue,Wed 19:24 Boston Logan (BOS) B 21:29 Chicago O'Hare (ORD) 3
AA 4778 Non-stop Embraer EMB 175 (E75) 3:05 Effective 2025-06-10 through 2025-06-25
This flight number is listed as serving the following routes:


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American Airlines flight AA 4778: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4778
05:49
Des Moines (DSM)

07:30
Chicago O'Hare (ORD) 3
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
05:59
Des Moines (DSM)

07:30
Chicago O'Hare (ORD) 3
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:31, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
06:49
Chicago O'Hare (ORD) 3

08:28
Kansas City (MCI)
Effective 2025-05-05 through 2025-05-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
06:49
Chicago O'Hare (ORD) 3

08:28
Kansas City (MCI)
Effective 2025-05-26 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
09:02
Kansas City (MCI)

10:43
Chicago O'Hare (ORD) 3
Effective 2025-05-05 through 2025-05-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
09:02
Kansas City (MCI)

10:43
Chicago O'Hare (ORD) 3
Effective 2025-05-26 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
14:54
Ronald Reagan Washington (DCA) 2

16:12
New York LaGuardia (LGA) B
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:18, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
19:14
Boston Logan (BOS) B

21:20
Chicago O'Hare (ORD) 3
Effective 2025-07-08 through 2025-08-05
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 3:06, non-stop
Embraer EMB 175 (E75)
American Airlines AA4778
19:24
Boston Logan (BOS) B

21:29
Chicago O'Hare (ORD) 3
Effective 2025-06-10 through 2025-06-25
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 3:05, non-stop
Embraer EMB 175 (E75)
This flight number is listed as serving the following routes:
  • Boston Logan (BOS) - Chicago O'Hare (ORD)
  • Des Moines (DSM) - Chicago O'Hare (ORD)
  • Kansas City (MCI) - Chicago O'Hare (ORD)
  • Ronald Reagan Washington (DCA) - New York LaGuardia (LGA)
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