Alaska Airlines flights from Knoxville (TYS) to Chicago O'Hare (ORD).

Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Mon,Thu-Sun 07:40 Knoxville (TYS) 08:52 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4446 Non-stop Canadair CRJ 700 (CR7) 2:12 Effective 2026-02-13 through 2026-03-07
Codeshare flight, operated by American Airlines.(AA 5325)
Tue,Wed 07:42 Knoxville (TYS) 08:54 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4446 Non-stop Canadair CRJ 700 (CR7) 2:12 Effective 2026-02-17 through 2026-03-04
Codeshare flight, operated by American Airlines.(AA 5325)
Daily 07:48 Knoxville (TYS) 08:50 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4446 Non-stop Canadair CRJ 700 (CR7) 2:02 Valid until 2026-01-05
Codeshare flight, operated by American Airlines.(AA 5325)
Thu 08:13 Knoxville (TYS) 09:25 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4446 Non-stop Canadair CRJ 700 (CR7) 2:12 Operates only on 2026-02-12
Codeshare flight, operated by American Airlines.(AA 5325)
Daily 12:55 Knoxville (TYS) 13:52 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4493 Non-stop Canadair CRJ 700 (CR7) 1:57 Effective 2026-08-06 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 5216)
Daily 17:37 Knoxville (TYS) 18:34 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4533 Non-stop Canadair CRJ 700 (CR7) 1:57 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 5225)
Daily 08:09 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4572 Non-stop Canadair CRJ 700 (CR7) 2:01 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 5195)
Daily 13:23 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4740 Non-stop Canadair CRJ 700 (CR7) 1:57 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 5197)
Thu 13:27 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4740 Non-stop Canadair CRJ 700 (CR7) 1:53 Operates only on 2026-05-21
Codeshare flight, operated by American Airlines.(AA 5434)
Mon-Fri,Sun 16:02 Knoxville (TYS) 17:09 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4740 Non-stop Canadair CRJ 700 (CR7) 2:07 Effective 2026-03-08 through 2026-04-06
Codeshare flight, operated by American Airlines.(AA 5228)
Sat 16:44 Knoxville (TYS) 17:55 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4740 Non-stop Canadair CRJ 700 (CR7) 2:11 Operates only on 2026-01-10
Codeshare flight, operated by American Airlines.(AA 5355)
Sat 16:44 Knoxville (TYS) 17:55 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4740 Non-stop Canadair CRJ 700 (CR7) 2:11 Effective 2026-01-24 through 2026-02-07
Codeshare flight, operated by American Airlines.(AA 5355)
Sat 17:08 Knoxville (TYS) 18:20 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4740 Non-stop Canadair CRJ 700 (CR7) 2:12 Valid until 2026-01-03
Codeshare flight, operated by American Airlines.(AA 5344)
Mon-Fri,Sun 17:15 Knoxville (TYS) 18:26 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4740 Non-stop Canadair CRJ 700 (CR7) 2:11 Effective 2026-01-06 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 5355)
Daily 18:52 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4756 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 5302)
Daily 18:56 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
Alaska Airlines AS 4756 Non-stop Canadair CRJ 700 (CR7) 1:54 Effective 2026-05-21 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 5302)
Daily 13:22 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6078 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 5202)
Daily 15:01 Knoxville (TYS) 16:09 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6113 Non-stop Embraer EMB 175 (E75) 2:08 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 4452)
Wed 12:55 Knoxville (TYS) 13:52 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6203 Non-stop Canadair CRJ 700 (CR7) 1:57 Operates only on 2026-08-05
Codeshare flight, operated by American Airlines.(AA 5216)
Daily 13:22 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6210 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 5420)
Daily 13:27 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6210 Non-stop Canadair CRJ 700 (CR7) 1:53 Effective 2026-05-22 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 5434)
Daily 15:08 Knoxville (TYS) 16:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6292 Non-stop Embraer EMB 175 (E75) 2:02 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 4553)
Daily 15:14 Knoxville (TYS) 16:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6292 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:56 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 3934)
Daily 05:11 Knoxville (TYS) 06:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6452 Non-stop Embraer EMB 175 (E75) 1:59 Effective 2026-05-21 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 4536)
Daily 05:17 Knoxville (TYS) 06:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6452 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:53 Effective 2026-04-07 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 3918)
Daily 17:04 Knoxville (TYS) 18:00 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6452 Non-stop Canadair CRJ 700 (CR7) 1:56 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 5168)
Daily 15:03 Knoxville (TYS) 16:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6454 Non-stop Canadair CRJ 700 (CR7) 2:07 Effective 2026-04-07 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 5467)
Daily 15:05 Knoxville (TYS) 16:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6454 Non-stop Embraer EMB 175 (E75) 2:05 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 4431)
Daily 07:40 Knoxville (TYS) 08:48 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 2:08 Effective 2026-03-08 through 2026-04-06
Codeshare flight, operated by American Airlines.(AA 5318)
Mon-Sat 07:54 Knoxville (TYS) 09:02 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 2:08 Effective 2026-01-06 through 2026-01-24
Codeshare flight, operated by American Airlines.(AA 5203)
Daily 07:54 Knoxville (TYS) 09:02 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 2:08 Effective 2026-01-25 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 5203)
Daily 08:05 Knoxville (TYS) 09:09 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 5379)
Daily 08:06 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2026-05-21 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 5379)
Daily 08:06 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 5379)
Sun 08:09 Knoxville (TYS) 09:17 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 2:08 Operates only on 2026-01-11
Codeshare flight, operated by American Airlines.(AA 5203)
Daily 08:11 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Canadair CRJ 700 (CR7) 1:59 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 5379)
Mon,Thu,Fri,Sun 15:01 Knoxville (TYS) 16:07 Chicago O'Hare (ORD) 3
Alaska Airlines AS 6872 Non-stop Embraer EMB 175 (E75) 2:06 Valid until 2026-01-05
Codeshare flight, operated by American Airlines.(AA 4495)


Alaska Airlines flights from Knoxville (TYS) to Chicago O'Hare (ORD).
Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:

Effective 2026-02-13 through 2026-03-07
Mon
Tue
-
Wed
-
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5325)
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 5325)
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5325)
Duration: 2:02, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Operates only on 2026-02-12
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 5325)
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-08-06 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5216)
Duration: 1:57, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5225)
Duration: 1:57, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5195)
Duration: 2:01, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5197)
Duration: 1:57, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Operates only on 2026-05-21
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 5434)
Duration: 1:53, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5228)
Duration: 2:07, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Operates only on 2026-01-10
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5355)
Duration: 2:11, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-01-24 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5355)
Duration: 2:11, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5344)
Duration: 2:12, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5355)
Duration: 2:11, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5302)
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5302)
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5202)
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4452)
Duration: 2:08, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Operates only on 2026-08-05
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 5216)
Duration: 1:57, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5420)
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-05-22 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5434)
Duration: 1:53, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4553)
Duration: 2:02, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3934)
Duration: 1:56, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Codeshare Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4536)
Duration: 1:59, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3918)
Duration: 1:53, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Codeshare Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5168)
Duration: 1:56, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5467)
Duration: 2:07, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4431)
Duration: 2:05, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5318)
Duration: 2:08, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-01-06 through 2026-01-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5203)
Duration: 2:08, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-01-25 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5203)
Duration: 2:08, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5379)
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5379)
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5379)
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Operates only on 2026-01-11
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5203)
Duration: 2:08, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5379)
Duration: 1:59, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Valid until 2026-01-05
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 4495)
Duration: 2:06, non-stop
Embraer EMB 175 (E75)
  • A domestic route departing from the Knoxville airport (TYS) and arriving at Chicago O'Hare airport (ORD).
  • The flight distance is 475 miles, or 764 km.
  • The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 1:53 and 2:12.