American Airlines flights from New York LaGuardia (LGA) to Saint Louis (STL).

FLIGHT SCHEDULE
Direct Flights:
Daily 16:30 New York LaGuardia (LGA) B 18:19 Saint Louis (STL) 1 American Airlines AA 598 Non-stop Airbus A319 (319) 2:49 Effective 2025-09-03 through 2025-10-05
Daily 10:20 New York LaGuardia (LGA) B 12:18 Saint Louis (STL) 1 American Airlines AA 2321 Non-stop Airbus A319 (319) 2:58 Effective 2025-09-03 through 2025-10-05
Daily 06:49 New York LaGuardia (LGA) B 08:27 Saint Louis (STL) 1 American Airlines AA 4339 Non-stop Embraer EMB 175 (E75) 2:38 Effective 2025-08-06 through 2025-09-02
Mon-Fri 06:59 New York LaGuardia (LGA) B 08:46 Saint Louis (STL) 1 American Airlines AA 4344 Non-stop Embraer EMB 175 (E75) 2:47 Effective 2025-06-05 through 2025-07-03
Mon-Fri 06:59 New York LaGuardia (LGA) B 08:41 Saint Louis (STL) 1 American Airlines AA 4344 Non-stop Embraer EMB 175 (E75) 2:42 Effective 2025-07-07 through 2025-08-05
Daily 18:55 New York LaGuardia (LGA) B 20:47 Saint Louis (STL) 1 American Airlines AA 4353 Non-stop Embraer EMB 175 (E75) 2:52 Valid until 2025-05-04
Sat 11:40 New York LaGuardia (LGA) B 13:23 Saint Louis (STL) 1 American Airlines AA 4366 Non-stop Embraer EMB 175 (E75) 2:43 Effective 2025-06-07 through 2025-06-28
Sat 11:40 New York LaGuardia (LGA) B 13:33 Saint Louis (STL) 1 American Airlines AA 4366 Non-stop Embraer EMB 175 (E75) 2:53 Effective 2025-07-05 through 2025-08-02
Thu,Sun 12:00 New York LaGuardia (LGA) B 13:42 Saint Louis (STL) 1 American Airlines AA 4366 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:42 Effective 2025-06-05 through 2025-06-08
Sun 12:00 New York LaGuardia (LGA) B 13:42 Saint Louis (STL) 1 American Airlines AA 4366 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:42 Effective 2025-06-15 through 2025-06-29
Mon-Fri,Sun 12:00 New York LaGuardia (LGA) B 13:47 Saint Louis (STL) 1 American Airlines AA 4366 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:47 Effective 2025-07-06 through 2025-08-05
Fri 12:02 New York LaGuardia (LGA) B 13:42 Saint Louis (STL) 1 American Airlines AA 4366 Non-stop Embraer EMB 175 (E75) 2:40 Operates only on 2025-07-04
Mon-Fri 12:40 New York LaGuardia (LGA) B 14:19 Saint Louis (STL) 1 American Airlines AA 4366 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:39 Effective 2025-06-06 through 2025-07-03
Daily 13:00 New York LaGuardia (LGA) B 14:44 Saint Louis (STL) 1 American Airlines AA 4367 Non-stop Embraer EMB 175 (E75) 2:44 Effective 2025-08-06 through 2025-09-02
Daily 06:59 New York LaGuardia (LGA) B 08:55 Saint Louis (STL) 1 American Airlines AA 4381 Non-stop Embraer EMB 175 (E75) 2:56 Effective 2025-10-06 through 2025-11-01
Daily 17:14 New York LaGuardia (LGA) B 19:17 Saint Louis (STL) 1 American Airlines AA 4383 Non-stop Embraer EMB 175 (E75) 3:03 Effective 2025-12-03 through 2025-12-17
Daily 17:49 New York LaGuardia (LGA) B 19:37 Saint Louis (STL) 1 American Airlines AA 4383 Non-stop Embraer EMB 175 (E75) 2:48 Effective 2025-10-26 through 2025-11-01
Daily 17:59 New York LaGuardia (LGA) B 19:48 Saint Louis (STL) 1 American Airlines AA 4383 Non-stop Embraer EMB 175 (E75) 2:49 Effective 2025-11-02 through 2025-12-02
Daily 18:05 New York LaGuardia (LGA) B 20:09 Saint Louis (STL) 1 American Airlines AA 4383 Non-stop Embraer EMB 175 (E75) 3:04 Effective 2026-01-06 through 2026-02-11
Daily 18:10 New York LaGuardia (LGA) B 20:09 Saint Louis (STL) 1 American Airlines AA 4383 Non-stop Embraer EMB 175 (E75) 2:59 Effective from 2026-02-12
Daily 12:29 New York LaGuardia (LGA) B 14:24 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 2:55 Effective 2025-12-03 through 2025-12-17
Daily 12:58 New York LaGuardia (LGA) B 14:45 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 2:47 Valid until 2025-05-04
Daily 12:58 New York LaGuardia (LGA) B 14:58 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 3:00 Effective 2026-01-06 through 2026-02-11
Daily 12:58 New York LaGuardia (LGA) B 14:55 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 2:57 Effective from 2026-02-12
Mon-Fri,Sun 13:10 New York LaGuardia (LGA) B 14:55 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 2:45 Effective 2025-05-05 through 2025-06-04
Daily 13:29 New York LaGuardia (LGA) B 15:18 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 2:49 Effective 2025-11-02 through 2025-12-02
Sat 13:35 New York LaGuardia (LGA) B 15:19 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 2:44 Effective 2025-05-10 through 2025-05-31
Daily 13:37 New York LaGuardia (LGA) B 15:31 Saint Louis (STL) 1 American Airlines AA 4461 Non-stop Embraer EMB 175 (E75) 2:54 Effective 2025-09-03 through 2025-10-05
Daily 09:00 New York LaGuardia (LGA) B 10:56 Saint Louis (STL) 1 American Airlines AA 4475 Non-stop Embraer EMB 175 (E75) 2:56 Effective 2025-12-03 through 2025-12-17
Daily 09:10 New York LaGuardia (LGA) B 11:05 Saint Louis (STL) 1 American Airlines AA 4475 Non-stop Embraer EMB 175 (E75) 2:55 Effective 2025-11-02 through 2025-12-02
Daily 09:10 New York LaGuardia (LGA) B 11:09 Saint Louis (STL) 1 American Airlines AA 4475 Non-stop Embraer EMB 175 (E75) 2:59 Effective 2025-12-18 through 2026-01-05
Daily 09:30 New York LaGuardia (LGA) B 11:32 Saint Louis (STL) 1 American Airlines AA 4475 Non-stop Embraer EMB 175 (E75) 3:02 Effective 2026-01-06 through 2026-02-11
Daily 09:35 New York LaGuardia (LGA) B 11:34 Saint Louis (STL) 1 American Airlines AA 4475 Non-stop Embraer EMB 175 (E75) 2:59 Effective from 2026-02-12
Mon-Fri,Sun 09:40 New York LaGuardia (LGA) B 11:32 Saint Louis (STL) 1 American Airlines AA 4479 Non-stop Embraer EMB 175 (E75) 2:52 Valid until 2025-05-02
Sun 09:45 New York LaGuardia (LGA) B 11:36 Saint Louis (STL) 1 American Airlines AA 4479 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:51 Operates only on 2025-05-04
Daily 21:10 New York LaGuardia (LGA) B 23:00 Saint Louis (STL) 1 American Airlines AA 4544 Non-stop Embraer EMB 175 (E75) 2:50 Effective 2025-12-18 through 2026-01-05
Mon-Thu,Sun 17:30 New York LaGuardia (LGA) B 19:15 Saint Louis (STL) 1 American Airlines AA 4613 Non-stop Embraer EMB 175 (E75) 2:45 Effective 2025-05-05 through 2025-06-04
Fri 17:59 New York LaGuardia (LGA) B 19:47 Saint Louis (STL) 1 American Airlines AA 4613 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:48 Effective 2025-05-09 through 2025-05-30
Daily 17:40 New York LaGuardia (LGA) B 19:23 Saint Louis (STL) 1 American Airlines AA 4728 Non-stop Embraer EMB 175 (E75) 2:43 Effective 2025-08-06 through 2025-09-02
Daily 17:49 New York LaGuardia (LGA) B 19:37 Saint Louis (STL) 1 American Airlines AA 4728 Non-stop Embraer EMB 175 (E75) 2:48 Effective 2025-10-06 through 2025-10-25
Mon-Fri,Sun 19:10 New York LaGuardia (LGA) B 20:55 Saint Louis (STL) 1 American Airlines AA 4728 Non-stop Embraer EMB 175 (E75) 2:45 Effective 2025-06-05 through 2025-07-03
Mon-Fri,Sun 19:13 New York LaGuardia (LGA) B 21:05 Saint Louis (STL) 1 American Airlines AA 4728 Non-stop Embraer EMB 175 (E75) 2:52 Effective 2025-07-06 through 2025-08-05
Mon-Fri 08:53 New York LaGuardia (LGA) B 10:43 Saint Louis (STL) 1 American Airlines AA 4790 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:50 Effective 2025-05-05 through 2025-06-04

A domestic route departing from the New York LaGuardia airport (LGA) and arriving at Saint Louis airport (STL).
The flight distance is 885 miles, or 1425 km.
The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
For direct flights, the flight time varies between 2:38 and 3:04.

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FLIGHT SCHEDULE

Direct Flights:

American Airlines AA598

16:30

New York LaGuardia (LGA) B

18:19

Saint Louis (STL) 1

Effective 2025-09-03 through 2025-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:49, non-stop
Airbus A319 (319)

American Airlines AA2321

10:20

New York LaGuardia (LGA) B

12:18

Saint Louis (STL) 1

Effective 2025-09-03 through 2025-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:58, non-stop
Airbus A319 (319)

American Airlines AA4339

06:49

New York LaGuardia (LGA) B

08:27

Saint Louis (STL) 1

Effective 2025-08-06 through 2025-09-02

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:38, non-stop
Embraer EMB 175 (E75)

American Airlines AA4344

06:59

New York LaGuardia (LGA) B

08:46

Saint Louis (STL) 1

Effective 2025-06-05 through 2025-07-03

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:47, non-stop
Embraer EMB 175 (E75)

American Airlines AA4344

06:59

New York LaGuardia (LGA) B

08:41

Saint Louis (STL) 1

Effective 2025-07-07 through 2025-08-05

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:42, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353

18:55

New York LaGuardia (LGA) B

20:47

Saint Louis (STL) 1

Valid until 2025-05-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:52, non-stop
Embraer EMB 175 (E75)

American Airlines AA4366

11:40

New York LaGuardia (LGA) B

13:23

Saint Louis (STL) 1

Effective 2025-06-07 through 2025-06-28

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:43, non-stop
Embraer EMB 175 (E75)

American Airlines AA4366

11:40

New York LaGuardia (LGA) B

13:33

Saint Louis (STL) 1

Effective 2025-07-05 through 2025-08-02

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:53, non-stop
Embraer EMB 175 (E75)

American Airlines AA4366

12:00

New York LaGuardia (LGA) B

13:42

Saint Louis (STL) 1

Effective 2025-06-05 through 2025-06-08

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun

Duration: 2:42, non-stop
Embraer EMB 170 / EMB 175 (E70)

American Airlines AA4366

12:00

New York LaGuardia (LGA) B

13:42

Saint Louis (STL) 1

Effective 2025-06-15 through 2025-06-29

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:42, non-stop
Embraer EMB 170 / EMB 175 (E70)

American Airlines AA4366

12:00

New York LaGuardia (LGA) B

13:47

Saint Louis (STL) 1

Effective 2025-07-06 through 2025-08-05

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:47, non-stop
Embraer EMB 170 / EMB 175 (E70)

American Airlines AA4366

12:02

New York LaGuardia (LGA) B

13:42

Saint Louis (STL) 1

Operates only on 2025-07-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Duration: 2:40, non-stop
Embraer EMB 175 (E75)

American Airlines AA4366

12:40

New York LaGuardia (LGA) B

14:19

Saint Louis (STL) 1

Effective 2025-06-06 through 2025-07-03

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:39, non-stop
Embraer EMB 170 / EMB 175 (E70)

American Airlines AA4367

13:00

New York LaGuardia (LGA) B

14:44

Saint Louis (STL) 1

Effective 2025-08-06 through 2025-09-02

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:44, non-stop
Embraer EMB 175 (E75)

American Airlines AA4381

06:59

New York LaGuardia (LGA) B

08:55

Saint Louis (STL) 1

Effective 2025-10-06 through 2025-11-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:56, non-stop
Embraer EMB 175 (E75)

American Airlines AA4383

17:14

New York LaGuardia (LGA) B

19:17

Saint Louis (STL) 1

Effective 2025-12-03 through 2025-12-17

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:03, non-stop
Embraer EMB 175 (E75)

American Airlines AA4383

17:49

New York LaGuardia (LGA) B

19:37

Saint Louis (STL) 1

Effective 2025-10-26 through 2025-11-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:48, non-stop
Embraer EMB 175 (E75)

American Airlines AA4383

17:59

New York LaGuardia (LGA) B

19:48

Saint Louis (STL) 1

Effective 2025-11-02 through 2025-12-02

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:49, non-stop
Embraer EMB 175 (E75)

American Airlines AA4383

18:05

New York LaGuardia (LGA) B

20:09

Saint Louis (STL) 1

Effective 2026-01-06 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:04, non-stop
Embraer EMB 175 (E75)

American Airlines AA4383

18:10

New York LaGuardia (LGA) B

20:09

Saint Louis (STL) 1

Effective from 2026-02-12

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:59, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

12:29

New York LaGuardia (LGA) B

14:24

Saint Louis (STL) 1

Effective 2025-12-03 through 2025-12-17

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:55, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

12:58

New York LaGuardia (LGA) B

14:45

Saint Louis (STL) 1

Valid until 2025-05-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:47, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

12:58

New York LaGuardia (LGA) B

14:58

Saint Louis (STL) 1

Effective 2026-01-06 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:00, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

12:58

New York LaGuardia (LGA) B

14:55

Saint Louis (STL) 1

Effective from 2026-02-12

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:57, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

13:10

New York LaGuardia (LGA) B

14:55

Saint Louis (STL) 1

Effective 2025-05-05 through 2025-06-04

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:45, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

13:29

New York LaGuardia (LGA) B

15:18

Saint Louis (STL) 1

Effective 2025-11-02 through 2025-12-02

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:49, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

13:35

New York LaGuardia (LGA) B

15:19

Saint Louis (STL) 1

Effective 2025-05-10 through 2025-05-31

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:44, non-stop
Embraer EMB 175 (E75)

American Airlines AA4461

13:37

New York LaGuardia (LGA) B

15:31

Saint Louis (STL) 1

Effective 2025-09-03 through 2025-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:54, non-stop
Embraer EMB 175 (E75)

American Airlines AA4475

09:00

New York LaGuardia (LGA) B

10:56

Saint Louis (STL) 1

Effective 2025-12-03 through 2025-12-17

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:56, non-stop
Embraer EMB 175 (E75)

American Airlines AA4475

09:10

New York LaGuardia (LGA) B

11:05

Saint Louis (STL) 1

Effective 2025-11-02 through 2025-12-02

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:55, non-stop
Embraer EMB 175 (E75)

American Airlines AA4475

09:10

New York LaGuardia (LGA) B

11:09

Saint Louis (STL) 1

Effective 2025-12-18 through 2026-01-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:59, non-stop
Embraer EMB 175 (E75)

American Airlines AA4475

09:30

New York LaGuardia (LGA) B

11:32

Saint Louis (STL) 1

Effective 2026-01-06 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:02, non-stop
Embraer EMB 175 (E75)

American Airlines AA4475

09:35

New York LaGuardia (LGA) B

11:34

Saint Louis (STL) 1

Effective from 2026-02-12

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:59, non-stop
Embraer EMB 175 (E75)

American Airlines AA4479

09:40

New York LaGuardia (LGA) B

11:32

Saint Louis (STL) 1

Valid until 2025-05-02

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:52, non-stop
Embraer EMB 175 (E75)

American Airlines AA4479

09:45

New York LaGuardia (LGA) B

11:36

Saint Louis (STL) 1

Operates only on 2025-05-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:51, non-stop
Embraer EMB 170 / EMB 175 (E70)

American Airlines AA4544

21:10

New York LaGuardia (LGA) B

23:00

Saint Louis (STL) 1

Effective 2025-12-18 through 2026-01-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:50, non-stop
Embraer EMB 175 (E75)

American Airlines AA4613

17:30

New York LaGuardia (LGA) B

19:15

Saint Louis (STL) 1

Effective 2025-05-05 through 2025-06-04

Mon

Tue

Wed

Thu

Fri
-

Sat
-

Sun

Duration: 2:45, non-stop
Embraer EMB 175 (E75)

American Airlines AA4613

17:59

New York LaGuardia (LGA) B

19:47

Saint Louis (STL) 1

Effective 2025-05-09 through 2025-05-30

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Duration: 2:48, non-stop
Embraer EMB 170 / EMB 175 (E70)

American Airlines AA4728

17:40

New York LaGuardia (LGA) B

19:23

Saint Louis (STL) 1

Effective 2025-08-06 through 2025-09-02

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:43, non-stop
Embraer EMB 175 (E75)

American Airlines AA4728

17:49

New York LaGuardia (LGA) B

19:37

Saint Louis (STL) 1

Effective 2025-10-06 through 2025-10-25

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:48, non-stop
Embraer EMB 175 (E75)

American Airlines AA4728

19:10

New York LaGuardia (LGA) B

20:55

Saint Louis (STL) 1

Effective 2025-06-05 through 2025-07-03

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:45, non-stop
Embraer EMB 175 (E75)

American Airlines AA4728

19:13

New York LaGuardia (LGA) B

21:05

Saint Louis (STL) 1

Effective 2025-07-06 through 2025-08-05

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:52, non-stop
Embraer EMB 175 (E75)

American Airlines AA4790

08:53

New York LaGuardia (LGA) B

10:43

Saint Louis (STL) 1

Effective 2025-05-05 through 2025-06-04

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:50, non-stop
Embraer EMB 170 / EMB 175 (E70)

A domestic route departing from the New York LaGuardia airport (LGA) and arriving at Saint Louis airport (STL).
The flight distance is 885 miles, or 1425 km.
The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
For direct flights, the flight time varies between 2:38 and 3:04.

All LGA-STL flights

All American Airlines flights

Return (STL-LGA) flights

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