All airlines flying from Saint Louis (STL) to Des Moines (DSM).

FLIGHT SCHEDULE
Direct Flights:
Wed,Thu 10:15 Saint Louis (STL) 2 11:25 Des Moines (DSM) Southwest Airlines WN 146 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Valid until 2026-01-01
Mon 22:25 Saint Louis (STL) 2 23:35 Des Moines (DSM) Southwest Airlines WN 146 Non-stop Boeing 737-800 (73H) 1:10 Operates only on 2026-01-05
Sat 22:45 Saint Louis (STL) 2 23:55 Des Moines (DSM) Southwest Airlines WN 146 Non-stop Boeing 737-700 (Scimitar Winglets) 1:10 Operates only on 2026-01-03
Mon,Tue,Fri,Sun 22:55 Saint Louis (STL) 2 00:05 Des Moines (DSM) Southwest Airlines WN 146 Non-stop Boeing 737-800 (73H) 1:10 Valid until 2026-01-04 The flight arrives 1 day after departure.
Thu,Fri,Sun 09:40 Saint Louis (STL) 2 10:50 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-01-11 through 2026-01-16
Mon,Sun 09:40 Saint Louis (STL) 2 10:50 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-01-19 through 2026-01-25
Thu,Fri,Sun 09:40 Saint Louis (STL) 2 10:50 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-02-01 through 2026-02-06
Mon,Sun 09:40 Saint Louis (STL) 2 10:50 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-02-09 through 2026-02-15
Mon,Tue,Thu 09:40 Saint Louis (STL) 2 10:50 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-02-17 through 2026-02-23
Mon 09:40 Saint Louis (STL) 2 10:50 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Operates only on 2026-03-02
Mon,Thu,Fri 09:45 Saint Louis (STL) 2 10:55 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-02-12 through 2026-02-16
Sat 09:45 Saint Louis (STL) 2 10:55 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737-700 (Scimitar Winglets) 1:10 Effective 2026-02-14 through 2026-02-28
Thu,Fri,Sun 09:45 Saint Louis (STL) 2 10:55 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-02-20 through 2026-03-01
Mon-Fri 10:15 Saint Louis (STL) 2 11:25 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-01-06 through 2026-01-14
Tue-Fri,Sun 10:15 Saint Louis (STL) 2 11:25 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-01-18 through 2026-01-23
Mon-Fri 10:15 Saint Louis (STL) 2 11:25 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-01-26 through 2026-02-04
Tue,Wed,Sun 10:15 Saint Louis (STL) 2 11:25 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-02-08 through 2026-02-11
Tue,Wed 10:15 Saint Louis (STL) 2 11:25 Des Moines (DSM) Southwest Airlines WN 364 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-02-18 through 2026-03-04
Mon 09:50 Saint Louis (STL) 2 11:00 Des Moines (DSM) Southwest Airlines WN 1351 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Operates only on 2026-01-05
Wed,Thu 20:25 Saint Louis (STL) 2 21:35 Des Moines (DSM) Southwest Airlines WN 1351 Non-stop Boeing 737-800 (73H) 1:10 Valid until 2026-01-01
Mon-Fri 20:00 Saint Louis (STL) 2 21:10 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-01-06 through 2026-01-14
Tue-Fri,Sun 20:00 Saint Louis (STL) 2 21:10 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-01-18 through 2026-01-23
Mon-Fri 20:00 Saint Louis (STL) 2 21:10 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-01-26 through 2026-02-04
Tue,Wed 20:00 Saint Louis (STL) 2 21:10 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-02-10 through 2026-02-11
Tue,Wed 20:00 Saint Louis (STL) 2 21:10 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-800 (73H) 1:10 Effective 2026-02-18 through 2026-03-04
Sun 20:45 Saint Louis (STL) 2 21:55 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-800 (73H) 1:10 Operates only on 2026-02-08
Thu,Fri,Sun 21:10 Saint Louis (STL) 2 22:15 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-700 (Scimitar Winglets) 1:05 Effective 2026-01-11 through 2026-01-16
Mon,Sun 21:10 Saint Louis (STL) 2 22:15 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-700 (Scimitar Winglets) 1:05 Effective 2026-01-19 through 2026-01-25
Thu,Fri,Sun 21:10 Saint Louis (STL) 2 22:15 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-700 (Scimitar Winglets) 1:05 Effective 2026-02-01 through 2026-02-06
Mon,Sun 21:10 Saint Louis (STL) 2 22:15 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-700 (Scimitar Winglets) 1:05 Effective 2026-02-09 through 2026-02-15
Tue,Thu 21:10 Saint Louis (STL) 2 22:15 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-700 (Scimitar Winglets) 1:05 Effective 2026-02-17 through 2026-02-19
Mon 21:10 Saint Louis (STL) 2 22:15 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-700 (Scimitar Winglets) 1:05 Operates only on 2026-03-02
Mon 21:20 Saint Louis (STL) 2 22:30 Des Moines (DSM) Southwest Airlines WN 1493 Non-stop Boeing 737-700 (Scimitar Winglets) 1:10 Operates only on 2026-02-23
Sat 13:45 Saint Louis (STL) 2 14:55 Des Moines (DSM) Southwest Airlines WN 1667 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2026-01-10 through 2026-02-07
Sat 09:45 Saint Louis (STL) 2 10:55 Des Moines (DSM) Southwest Airlines WN 2040 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Valid until 2026-01-03
Mon,Tue,Fri,Sun 09:50 Saint Louis (STL) 2 11:00 Des Moines (DSM) Southwest Airlines WN 2040 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Valid until 2026-01-04
Mon,Thu,Fri 22:25 Saint Louis (STL) 2 23:35 Des Moines (DSM) Southwest Airlines WN 3770 Non-stop Boeing 737-700 (Scimitar Winglets) 1:10 Effective 2026-02-12 through 2026-02-16
Thu,Fri,Sun 22:25 Saint Louis (STL) 2 23:35 Des Moines (DSM) Southwest Airlines WN 3770 Non-stop Boeing 737-700 (Scimitar Winglets) 1:10 Effective 2026-02-20 through 2026-03-01

A domestic route departing from the Saint Louis airport (STL) and arriving at Des Moines airport (DSM).
The flight distance is 259 miles, or 417 km.
The timezone of both the departure and the arrival airports is UTC-6 . Current time at both airports is (loading...).
For direct flights, the flight time varies between 1:05 and 1:10.

Return (DSM-STL) flights

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All airlines flying from Saint Louis (STL) to Des Moines (DSM).

FLIGHT SCHEDULE

Direct Flights:

Southwest Airlines WN146

10:15

Saint Louis (STL) 2

11:25

Des Moines (DSM)

Valid until 2026-01-01

Mon
-

Tue
-

Wed

Thu

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN146

22:25

Saint Louis (STL) 2

23:35

Des Moines (DSM)

Operates only on 2026-01-05

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN146

22:45

Saint Louis (STL) 2

23:55

Des Moines (DSM)

Operates only on 2026-01-03

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:10, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN146

22:55

Saint Louis (STL) 2

00:05(+1)

Des Moines (DSM)

Valid until 2026-01-04

Mon

Tue

Wed
-

Thu
-

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737-800 (73H)
The flight arrives 1 day after departure.

Direct Flights:

Southwest Airlines WN364

09:40

Saint Louis (STL) 2

10:50

Des Moines (DSM)

Effective 2026-01-11 through 2026-01-16

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

09:40

Saint Louis (STL) 2

10:50

Des Moines (DSM)

Effective 2026-01-19 through 2026-01-25

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

09:40

Saint Louis (STL) 2

10:50

Des Moines (DSM)

Effective 2026-02-01 through 2026-02-06

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

09:40

Saint Louis (STL) 2

10:50

Des Moines (DSM)

Effective 2026-02-09 through 2026-02-15

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

09:40

Saint Louis (STL) 2

10:50

Des Moines (DSM)

Effective 2026-02-17 through 2026-02-23

Mon

Tue

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

09:40

Saint Louis (STL) 2

10:50

Des Moines (DSM)

Operates only on 2026-03-02

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

09:45

Saint Louis (STL) 2

10:55

Des Moines (DSM)

Effective 2026-02-12 through 2026-02-16

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

09:45

Saint Louis (STL) 2

10:55

Des Moines (DSM)

Effective 2026-02-14 through 2026-02-28

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:10, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN364

09:45

Saint Louis (STL) 2

10:55

Des Moines (DSM)

Effective 2026-02-20 through 2026-03-01

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN364

10:15

Saint Louis (STL) 2

11:25

Des Moines (DSM)

Effective 2026-01-06 through 2026-01-14

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN364

10:15

Saint Louis (STL) 2

11:25

Des Moines (DSM)

Effective 2026-01-18 through 2026-01-23

Mon
-

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN364

10:15

Saint Louis (STL) 2

11:25

Des Moines (DSM)

Effective 2026-01-26 through 2026-02-04

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN364

10:15

Saint Louis (STL) 2

11:25

Des Moines (DSM)

Effective 2026-02-08 through 2026-02-11

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN364

10:15

Saint Louis (STL) 2

11:25

Des Moines (DSM)

Effective 2026-02-18 through 2026-03-04

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1351

09:50

Saint Louis (STL) 2

11:00

Des Moines (DSM)

Operates only on 2026-01-05

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN1351

20:25

Saint Louis (STL) 2

21:35

Des Moines (DSM)

Valid until 2026-01-01

Mon
-

Tue
-

Wed

Thu

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1493

20:00

Saint Louis (STL) 2

21:10

Des Moines (DSM)

Effective 2026-01-06 through 2026-01-14

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1493

20:00

Saint Louis (STL) 2

21:10

Des Moines (DSM)

Effective 2026-01-18 through 2026-01-23

Mon
-

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1493

20:00

Saint Louis (STL) 2

21:10

Des Moines (DSM)

Effective 2026-01-26 through 2026-02-04

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1493

20:00

Saint Louis (STL) 2

21:10

Des Moines (DSM)

Effective 2026-02-10 through 2026-02-11

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1493

20:00

Saint Louis (STL) 2

21:10

Des Moines (DSM)

Effective 2026-02-18 through 2026-03-04

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1493

20:45

Saint Louis (STL) 2

21:55

Des Moines (DSM)

Operates only on 2026-02-08

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737-800 (73H)

Direct Flights:

Southwest Airlines WN1493

21:10

Saint Louis (STL) 2

22:15

Des Moines (DSM)

Effective 2026-01-11 through 2026-01-16

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:05, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN1493

21:10

Saint Louis (STL) 2

22:15

Des Moines (DSM)

Effective 2026-01-19 through 2026-01-25

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:05, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN1493

21:10

Saint Louis (STL) 2

22:15

Des Moines (DSM)

Effective 2026-02-01 through 2026-02-06

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:05, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN1493

21:10

Saint Louis (STL) 2

22:15

Des Moines (DSM)

Effective 2026-02-09 through 2026-02-15

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 1:05, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN1493

21:10

Saint Louis (STL) 2

22:15

Des Moines (DSM)

Effective 2026-02-17 through 2026-02-19

Mon
-

Tue

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Duration: 1:05, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN1493

21:10

Saint Louis (STL) 2

22:15

Des Moines (DSM)

Operates only on 2026-03-02

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:05, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN1493

21:20

Saint Louis (STL) 2

22:30

Des Moines (DSM)

Operates only on 2026-02-23

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN1667

13:45

Saint Louis (STL) 2

14:55

Des Moines (DSM)

Effective 2026-01-10 through 2026-02-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN2040

09:45

Saint Louis (STL) 2

10:55

Des Moines (DSM)

Valid until 2026-01-03

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN2040

09:50

Saint Louis (STL) 2

11:00

Des Moines (DSM)

Valid until 2026-01-04

Mon

Tue

Wed
-

Thu
-

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

Southwest Airlines WN3770

22:25

Saint Louis (STL) 2

23:35

Des Moines (DSM)

Effective 2026-02-12 through 2026-02-16

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun
-

Duration: 1:10, non-stop
Boeing 737-700 (Scimitar Winglets)

Direct Flights:

Southwest Airlines WN3770

22:25

Saint Louis (STL) 2

23:35

Des Moines (DSM)

Effective 2026-02-20 through 2026-03-01

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Duration: 1:10, non-stop
Boeing 737-700 (Scimitar Winglets)

A domestic route departing from the Saint Louis airport (STL) and arriving at Des Moines airport (DSM).
The flight distance is 259 miles, or 417 km.
The timezone of both the departure and the arrival airports is UTC-6 . Current time at both airports is (loading...).
For direct flights, the flight time varies between 1:05 and 1:10.

Return (DSM-STL) flights

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