All airlines flying from Medellin Jose Maria Cordova Intl (MDE) to Guayaquil (GYE).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Fri 16:55 Medellin Jose Maria Cordova Intl (MDE) 18:45 Guayaquil (GYE)
Avianca AV 135 Non-stop Airbus A320neo (32N) 1:50 Effective 2026-04-03 through 2026-10-23
Mon,Wed 18:35 Medellin Jose Maria Cordova Intl (MDE) 20:25 Guayaquil (GYE)
Avianca AV 135 Non-stop Airbus A320neo (32N) 1:50 Effective 2026-03-30 through 2026-10-21
Mon 16:10 Medellin Jose Maria Cordova Intl (MDE) 18:10 Guayaquil (GYE)
Avianca AV 8399 Non-stop Airbus A320neo (32N) 2:00 Valid until 2026-03-23
Mon 16:10 Medellin Jose Maria Cordova Intl (MDE) 18:10 Guayaquil (GYE)
Avianca AV 8399 Non-stop Airbus A320neo (32N) 2:00 Effective from 2026-10-26
Fri 16:30 Medellin Jose Maria Cordova Intl (MDE) 18:30 Guayaquil (GYE)
Avianca AV 8399 Non-stop Airbus A320neo (32N) 2:00 Valid until 2026-03-27
Fri 16:30 Medellin Jose Maria Cordova Intl (MDE) 18:30 Guayaquil (GYE)
Avianca AV 8399 Non-stop Airbus A320neo (32N) 2:00 Effective from 2026-10-30
Wed 18:25 Medellin Jose Maria Cordova Intl (MDE) 20:25 Guayaquil (GYE)
Avianca AV 8399 Non-stop Airbus A320 (320) 2:00 Valid until 2026-03-25
Wed 18:25 Medellin Jose Maria Cordova Intl (MDE) 20:25 Guayaquil (GYE)
Avianca AV 8399 Non-stop Airbus A320 (320) 2:00 Effective from 2026-10-28


All airlines flying from Medellin Jose Maria Cordova Intl (MDE) to Guayaquil (GYE).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:

Effective 2026-04-03 through 2026-10-23
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:50, non-stop
Airbus A320neo (32N)

Direct Flights:

Effective 2026-03-30 through 2026-10-21
Mon
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:50, non-stop
Airbus A320neo (32N)

Direct Flights:

Valid until 2026-03-23
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:00, non-stop
Airbus A320neo (32N)

Direct Flights:

Effective from 2026-10-26
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:00, non-stop
Airbus A320neo (32N)

Direct Flights:

Valid until 2026-03-27
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:00, non-stop
Airbus A320neo (32N)

Direct Flights:

Effective from 2026-10-30
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:00, non-stop
Airbus A320neo (32N)

Direct Flights:

Valid until 2026-03-25
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:00, non-stop
Airbus A320 (320)

Direct Flights:

Effective from 2026-10-28
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:00, non-stop
Airbus A320 (320)
  • An international route departing from Medellin Jose Maria Cordova Intl airport, Colombia (MDE) and arriving at Guayaquil airport, Ecuador (GYE).
  • The flight distance is 649 miles, or 1045 km.
  • The timezone of both the departure and the arrival airports is UTC-5 . Current time at both airports is (loading...).
  • For direct flights, the flight time varies between 1:50 and 2:00.