All airlines flying from Guarulhos, Sao Paulo (GRU) to Istanbul (IST).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 04:05 Guarulhos, Sao Paulo (GRU) 3 22:35 Istanbul (IST)
Turkish Airlines TK 16 Non-stop Airbus A350-900 (359) 12:30 Effective from 2025-10-26
Daily 04:10 Guarulhos, Sao Paulo (GRU) 3 22:55 Istanbul (IST)
Turkish Airlines TK 16 Non-stop Airbus A350-900 (359) 12:45 Valid until 2025-09-09
Mon,Tue,Thu-Sun 04:10 Guarulhos, Sao Paulo (GRU) 3 22:55 Istanbul (IST)
Turkish Airlines TK 16 Non-stop Airbus A350-900 (359) 12:45 Effective 2025-09-11 through 2025-10-07
Daily 04:10 Guarulhos, Sao Paulo (GRU) 3 22:55 Istanbul (IST)
Turkish Airlines TK 16 Non-stop Airbus A350-900 (359) 12:45 Effective 2025-10-08 through 2025-10-25
Tue,Thu,Fri,Sun 16:10 Guarulhos, Sao Paulo (GRU) 3 10:55 Istanbul (IST)
Turkish Airlines TK 216 Non-stop Airbus A350-900 (359) 12:45 Valid until 2025-10-24
The flight arrives 1 day after departure.
Tue,Thu,Fri,Sun 16:50 Guarulhos, Sao Paulo (GRU) 3 11:20 Istanbul (IST)
Turkish Airlines TK 216 Non-stop Airbus A350-900 (359) 12:30 Effective 2025-10-26 through 2026-01-09
The flight arrives 1 day after departure.
Mon,Tue,Thu-Sun 16:50 Guarulhos, Sao Paulo (GRU) 3 11:20 Istanbul (IST)
Turkish Airlines TK 216 Non-stop Airbus A350-900 (359) 12:30 Effective from 2026-01-10
The flight arrives 1 day after departure.
Non-Direct Flights:
Thu 01:55 Guarulhos, Sao Paulo (GRU) 23:05 Istanbul (IST)
Turkish Airlines TK 6410 1-stop Boeing 777-200 Freighter (77X) 15:10
This is a Scheduled Cargo flight.
Tue 05:25 Guarulhos, Sao Paulo (GRU) 02:40 Istanbul (IST)
Turkish Airlines TK 6440 1-stop Boeing 777-200 Freighter (77X) 15:15
The flight arrives 1 day after departure.
This is a Scheduled Cargo flight.
Direct Codeshare Flights:
Tue,Thu,Fri,Sun 16:10 Guarulhos, Sao Paulo (GRU) 3 10:55 Istanbul (IST)
Air Serbia JU 8289 Non-stop Airbus A350-900 (359) 12:45
Codeshare flight, operated by Turkish Airlines.(TK 216)
The flight arrives 1 day after departure.
Daily 04:10 Guarulhos, Sao Paulo (GRU) 3 22:55 Istanbul (IST)
EgyptAir MS 9364 Non-stop Airbus A350-900 (359) 12:45 Valid until 2025-09-09
Codeshare flight, operated by Turkish Airlines.(TK 16)
Mon,Tue,Thu-Sun 04:10 Guarulhos, Sao Paulo (GRU) 3 22:55 Istanbul (IST)
EgyptAir MS 9364 Non-stop Airbus A350-900 (359) 12:45 Effective 2025-09-11 through 2025-10-07
Codeshare flight, operated by Turkish Airlines.(TK 16)
Daily 04:10 Guarulhos, Sao Paulo (GRU) 3 22:55 Istanbul (IST)
EgyptAir MS 9364 Non-stop Airbus A350-900 (359) 12:45 Effective 2025-10-08 through 2025-10-25
Codeshare flight, operated by Turkish Airlines.(TK 16)
Tue,Thu,Fri,Sun 16:10 Guarulhos, Sao Paulo (GRU) 3 10:55 Istanbul (IST)
ANA NH 9668 Non-stop Airbus A350-900 (359) 12:45 Valid until 2025-10-24
Codeshare flight, operated by Turkish Airlines.(TK 216)
The flight arrives 1 day after departure.




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All airlines flying from Guarulhos, Sao Paulo (GRU) to Istanbul (IST).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Turkish Airlines TK16
04:05
Guarulhos, Sao Paulo (GRU) 3

22:35
Istanbul (IST)
Effective from 2025-10-26
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 12:30, non-stop
Airbus A350-900 (359)
Turkish Airlines TK16
04:10
Guarulhos, Sao Paulo (GRU) 3

22:55
Istanbul (IST)
Valid until 2025-09-09
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 12:45, non-stop
Airbus A350-900 (359)
Turkish Airlines TK16
04:10
Guarulhos, Sao Paulo (GRU) 3

22:55
Istanbul (IST)
Effective 2025-09-11 through 2025-10-07
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 12:45, non-stop
Airbus A350-900 (359)
Turkish Airlines TK16
04:10
Guarulhos, Sao Paulo (GRU) 3

22:55
Istanbul (IST)
Effective 2025-10-08 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 12:45, non-stop
Airbus A350-900 (359)
Turkish Airlines TK216
16:10
Guarulhos, Sao Paulo (GRU) 3

10:55(+1)
Istanbul (IST)
Valid until 2025-10-24
Mon
-
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 12:45, non-stop
Airbus A350-900 (359)
The flight arrives 1 day after departure.
Turkish Airlines TK216
16:50
Guarulhos, Sao Paulo (GRU) 3

11:20(+1)
Istanbul (IST)
Effective 2025-10-26 through 2026-01-09
Mon
-
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 12:30, non-stop
Airbus A350-900 (359)
The flight arrives 1 day after departure.
Turkish Airlines TK216
16:50
Guarulhos, Sao Paulo (GRU) 3

11:20(+1)
Istanbul (IST)
Effective from 2026-01-10
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 12:30, non-stop
Airbus A350-900 (359)
The flight arrives 1 day after departure.
Non-Direct Flights:
Turkish Airlines TK6410
01:55
Guarulhos, Sao Paulo (GRU)

23:05
Istanbul (IST)
This is a Scheduled Cargo flight.
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 15:10, 1-stop
Boeing 777-200 Freighter (77X)
Turkish Airlines TK6440
05:25
Guarulhos, Sao Paulo (GRU)

02:40(+1)
Istanbul (IST)
This is a Scheduled Cargo flight.
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 15:15, 1-stop
Boeing 777-200 Freighter (77X)
The flight arrives 1 day after departure.
Direct Codeshare Flights:
Air Serbia JU8289
16:10
Guarulhos, Sao Paulo (GRU) 3

10:55(+1)
Istanbul (IST)
Mon
-
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Turkish Airlines. (TK 216)
Duration: 12:45, non-stop
Airbus A350-900 (359)
The flight arrives 1 day after departure.
EgyptAir MS9364
04:10
Guarulhos, Sao Paulo (GRU) 3

22:55
Istanbul (IST)
Valid until 2025-09-09
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 16)
Duration: 12:45, non-stop
Airbus A350-900 (359)
EgyptAir MS9364
04:10
Guarulhos, Sao Paulo (GRU) 3

22:55
Istanbul (IST)
Effective 2025-09-11 through 2025-10-07
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 16)
Duration: 12:45, non-stop
Airbus A350-900 (359)
EgyptAir MS9364
04:10
Guarulhos, Sao Paulo (GRU) 3

22:55
Istanbul (IST)
Effective 2025-10-08 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 16)
Duration: 12:45, non-stop
Airbus A350-900 (359)
ANA NH9668
16:10
Guarulhos, Sao Paulo (GRU) 3

10:55(+1)
Istanbul (IST)
Valid until 2025-10-24
Mon
-
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Turkish Airlines. (TK 216)
Duration: 12:45, non-stop
Airbus A350-900 (359)
The flight arrives 1 day after departure.
  • An international route departing from Guarulhos, Sao Paulo airport, Brazil (GRU) and arriving at Istanbul airport, Turkey (IST).
  • The flight distance is 6556 miles, or 10551 km.
  • The timezone of the departure airport is UTC-3 , and the timezone of the arrival airport is UTC+3 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 12:30 and 12:45.
Return (IST-GRU) flights
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