All airlines flying from Charlotte (CLT) to Key West (EYW).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 16:15 Charlotte (CLT) 18:23 Key West (EYW)
American Airlines AA 642 Non-stop Airbus A319 (319) 2:08 Effective 2026-04-07 through 2026-05-20
Mon-Fri,Sun 15:40 Charlotte (CLT) 18:01 Key West (EYW)
American Airlines AA 1365 Non-stop Airbus A319 (319) 2:21 Effective 2026-01-06 through 2026-02-11
Sat 15:45 Charlotte (CLT) 18:06 Key West (EYW)
American Airlines AA 1365 Non-stop Airbus A319 (319) 2:21 Effective 2026-01-10 through 2026-02-07
Tue,Wed 20:04 Charlotte (CLT) 22:23 Key West (EYW)
American Airlines AA 1365 Non-stop Airbus A319 (319) 2:19 Effective 2026-02-17 through 2026-03-04
Tue 20:04 Charlotte (CLT) 22:18 Key West (EYW)
American Airlines AA 1365 Non-stop Airbus A319 (319) 2:14 Effective 2026-03-10 through 2026-03-31
Mon,Thu-Sun 20:23 Charlotte (CLT) 22:43 Key West (EYW)
American Airlines AA 1365 Non-stop Airbus A319 (319) 2:20 Effective 2026-02-12 through 2026-03-07
Mon,Wed-Sun 20:23 Charlotte (CLT) 22:37 Key West (EYW)
American Airlines AA 1365 Non-stop Airbus A319 (319) 2:14 Effective 2026-03-08 through 2026-04-06
Daily 08:55 Charlotte (CLT) 11:21 Key West (EYW)
American Airlines AA 1816 Non-stop Airbus A319 (319) 2:26 Effective 2026-09-09 through 2026-10-04
Daily 09:39 Charlotte (CLT) 11:59 Key West (EYW)
American Airlines AA 1816 Non-stop Airbus A319 (319) 2:20 Effective 2026-08-05 through 2026-09-08
Daily 13:35 Charlotte (CLT) 15:57 Key West (EYW)
American Airlines AA 1818 Non-stop Airbus A319 (319) 2:22 Valid until 2026-01-05
Daily 13:35 Charlotte (CLT) 15:56 Key West (EYW)
American Airlines AA 1818 Non-stop Airbus A319 (319) 2:21 Effective 2026-02-12 through 2026-03-07
Daily 13:35 Charlotte (CLT) 15:57 Key West (EYW)
American Airlines AA 1818 Non-stop Airbus A319 (319) 2:22 Effective 2026-03-08 through 2026-04-06
Daily 08:55 Charlotte (CLT) 11:11 Key West (EYW)
American Airlines AA 1823 Non-stop Airbus A319 (319) 2:16 Effective 2026-07-02 through 2026-08-04
Daily 08:55 Charlotte (CLT) 11:14 Key West (EYW)
American Airlines AA 1826 Non-stop Airbus A319 (319) 2:19 Effective 2026-05-21 through 2026-07-01
Daily 11:00 Charlotte (CLT) 13:03 Key West (EYW)
American Airlines AA 2073 Non-stop Airbus A319 (319) 2:03 Effective 2026-04-07 through 2026-05-20
Daily 08:55 Charlotte (CLT) 11:14 Key West (EYW)
American Airlines AA 2076 Non-stop Airbus A319 (319) 2:19 Effective 2026-04-07 through 2026-05-20
Daily 14:30 Charlotte (CLT) 16:40 Key West (EYW)
American Airlines AA 2077 Non-stop Airbus A319 (319) 2:10 Effective 2026-04-07 through 2026-05-20
Mon,Wed-Sun 08:55 Charlotte (CLT) 11:20 Key West (EYW)
American Airlines AA 2199 Non-stop Airbus A319 (319) 2:25 Effective 2026-03-08 through 2026-04-06
Tue 09:34 Charlotte (CLT) 12:00 Key West (EYW)
American Airlines AA 2199 Non-stop Airbus A319 (319) 2:26 Effective 2026-03-10 through 2026-03-31
Fri 08:40 Charlotte (CLT) 11:01 Key West (EYW)
American Airlines AA 2654 Non-stop Airbus A319 (319) 2:21 Effective 2026-02-13 through 2026-03-06
Mon,Thu,Sat 08:41 Charlotte (CLT) 11:02 Key West (EYW)
American Airlines AA 2654 Non-stop Airbus A319 (319) 2:21 Effective 2026-02-12 through 2026-03-07
Tue,Wed 08:51 Charlotte (CLT) 11:10 Key West (EYW)
American Airlines AA 2654 Non-stop Airbus A319 (319) 2:19 Effective 2026-02-17 through 2026-03-04
Daily 08:55 Charlotte (CLT) 11:23 Key West (EYW)
American Airlines AA 2677 Non-stop Airbus A319 (319) 2:28 Effective from 2026-10-05
Sat 10:37 Charlotte (CLT) 13:07 Key West (EYW)
American Airlines AA 2839 Non-stop Airbus A319 (319) 2:30 Effective 2026-02-14 through 2026-03-07
Mon,Thu,Fri,Sun 10:52 Charlotte (CLT) 13:22 Key West (EYW)
American Airlines AA 2839 Non-stop Airbus A319 (319) 2:30 Effective 2026-02-12 through 2026-03-06
Mon,Wed-Sun 11:00 Charlotte (CLT) 13:26 Key West (EYW)
American Airlines AA 2839 Non-stop Airbus A319 (319) 2:26 Effective 2026-03-08 through 2026-04-06
Tue 12:15 Charlotte (CLT) 14:40 Key West (EYW)
American Airlines AA 2839 Non-stop Airbus A319 (319) 2:25 Effective 2026-03-10 through 2026-03-31
Tue,Wed 12:20 Charlotte (CLT) 14:39 Key West (EYW)
American Airlines AA 2839 Non-stop Airbus A319 (319) 2:19 Effective 2026-02-17 through 2026-03-04
Daily 19:30 Charlotte (CLT) 21:47 Key West (EYW)
American Airlines AA 2839 Non-stop Airbus A319 (319) 2:17 Effective 2026-01-06 through 2026-02-11
Mon,Wed-Sun 20:23 Charlotte (CLT) 22:44 Key West (EYW)
American Airlines AA 2839 Non-stop Airbus A319 (319) 2:21 Valid until 2026-01-05
Sun 08:41 Charlotte (CLT) 11:02 Key West (EYW)
American Airlines AA 2856 Non-stop Airbus A319 (319) 2:21 Effective 2026-02-22 through 2026-03-01
Daily 09:33 Charlotte (CLT) 12:08 Key West (EYW)
American Airlines AA 2856 Non-stop Airbus A319 (319) 2:35 Valid until 2026-01-05
Daily 10:20 Charlotte (CLT) 12:42 Key West (EYW)
American Airlines AA 2856 Non-stop Airbus A319 (319) 2:22 Effective 2026-01-06 through 2026-02-11
Daily 11:05 Charlotte (CLT) 13:25 Key West (EYW)
American Airlines AA 3338 Non-stop Embraer EMB 175 (E75) 2:20 Effective from 2026-10-05
Daily 13:05 Charlotte (CLT) 15:20 Key West (EYW)
American Airlines AA 3351 Non-stop Embraer EMB 175 (E75) 2:15 Effective from 2026-10-05
Daily 11:05 Charlotte (CLT) 13:31 Key West (EYW)
American Airlines AA 3419 Non-stop Embraer EMB 175 (E75) 2:26 Effective 2026-09-09 through 2026-10-04
Daily 13:05 Charlotte (CLT) 15:21 Key West (EYW)
American Airlines AA 3420 Non-stop Embraer EMB 175 (E75) 2:16 Effective 2026-09-09 through 2026-10-04
Daily 11:45 Charlotte (CLT) 14:05 Key West (EYW)
American Airlines AA 3432 Non-stop Embraer EMB 175 (E75) 2:20 Effective 2026-08-05 through 2026-09-08
Daily 11:05 Charlotte (CLT) 13:29 Key West (EYW)
American Airlines AA 3512 Non-stop Embraer EMB 175 (E75) 2:24 Effective 2026-07-02 through 2026-08-04
Daily 11:05 Charlotte (CLT) 13:28 Key West (EYW)
American Airlines AA 3514 Non-stop Embraer EMB 175 (E75) 2:23 Effective 2026-05-21 through 2026-07-01
Daily 13:05 Charlotte (CLT) 15:23 Key West (EYW)
American Airlines AA 3517 Non-stop Embraer EMB 175 (E75) 2:18 Effective 2026-07-02 through 2026-08-04
Daily 13:05 Charlotte (CLT) 15:22 Key West (EYW)
American Airlines AA 3519 Non-stop Embraer EMB 175 (E75) 2:17 Effective 2026-05-21 through 2026-07-01
Mon-Fri,Sun 12:28 Charlotte (CLT) 14:54 Key West (EYW)
American Airlines AA 3752 Non-stop Embraer EMB 175 (E75) 2:26 Effective 2026-01-06 through 2026-02-11
Sat 13:15 Charlotte (CLT) 15:41 Key West (EYW)
American Airlines AA 3752 Non-stop Embraer EMB 175 (E75) 2:26 Effective 2026-01-10 through 2026-02-07
Daily 14:06 Charlotte (CLT) 16:20 Key West (EYW)
American Airlines AA 3822 Non-stop Embraer EMB 175 (E75) 2:14 Effective 2026-08-05 through 2026-09-08
Daily 11:50 Charlotte (CLT) 14:14 Key West (EYW)
American Airlines AA 3854 Non-stop Embraer EMB 175 (E75) 2:24 Valid until 2026-01-05




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All airlines flying from Charlotte (CLT) to Key West (EYW).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA642
16:15
Charlotte (CLT)

18:23
Key West (EYW)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1365
15:40
Charlotte (CLT)

18:01
Key West (EYW)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:21, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1365
15:45
Charlotte (CLT)

18:06
Key West (EYW)
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:21, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1365
20:04
Charlotte (CLT)

22:23
Key West (EYW)
Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:19, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1365
20:04
Charlotte (CLT)

22:18
Key West (EYW)
Effective 2026-03-10 through 2026-03-31
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:14, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1365
20:23
Charlotte (CLT)

22:43
Key West (EYW)
Effective 2026-02-12 through 2026-03-07
Mon
Tue
-
Wed
-
Thu
Fri
Sat
Sun
Duration: 2:20, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1365
20:23
Charlotte (CLT)

22:37
Key West (EYW)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 2:14, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1816
08:55
Charlotte (CLT)

11:21
Key West (EYW)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:26, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1816
09:39
Charlotte (CLT)

11:59
Key West (EYW)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:20, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1818
13:35
Charlotte (CLT)

15:57
Key West (EYW)
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:22, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1818
13:35
Charlotte (CLT)

15:56
Key West (EYW)
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:21, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1818
13:35
Charlotte (CLT)

15:57
Key West (EYW)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:22, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1823
08:55
Charlotte (CLT)

11:11
Key West (EYW)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:16, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA1826
08:55
Charlotte (CLT)

11:14
Key West (EYW)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:19, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2073
11:00
Charlotte (CLT)

13:03
Key West (EYW)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:03, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2076
08:55
Charlotte (CLT)

11:14
Key West (EYW)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:19, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2077
14:30
Charlotte (CLT)

16:40
Key West (EYW)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:10, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2199
08:55
Charlotte (CLT)

11:20
Key West (EYW)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 2:25, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2199
09:34
Charlotte (CLT)

12:00
Key West (EYW)
Effective 2026-03-10 through 2026-03-31
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:26, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2654
08:40
Charlotte (CLT)

11:01
Key West (EYW)
Effective 2026-02-13 through 2026-03-06
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:21, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2654
08:41
Charlotte (CLT)

11:02
Key West (EYW)
Effective 2026-02-12 through 2026-03-07
Mon
Tue
-
Wed
-
Thu
Fri
-
Sat
Sun
-
Duration: 2:21, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2654
08:51
Charlotte (CLT)

11:10
Key West (EYW)
Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:19, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2677
08:55
Charlotte (CLT)

11:23
Key West (EYW)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:28, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2839
10:37
Charlotte (CLT)

13:07
Key West (EYW)
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:30, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2839
10:52
Charlotte (CLT)

13:22
Key West (EYW)
Effective 2026-02-12 through 2026-03-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 2:30, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2839
11:00
Charlotte (CLT)

13:26
Key West (EYW)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 2:26, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2839
12:15
Charlotte (CLT)

14:40
Key West (EYW)
Effective 2026-03-10 through 2026-03-31
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:25, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2839
12:20
Charlotte (CLT)

14:39
Key West (EYW)
Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:19, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2839
19:30
Charlotte (CLT)

21:47
Key West (EYW)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2839
20:23
Charlotte (CLT)

22:44
Key West (EYW)
Valid until 2026-01-05
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 2:21, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2856
08:41
Charlotte (CLT)

11:02
Key West (EYW)
Effective 2026-02-22 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:21, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2856
09:33
Charlotte (CLT)

12:08
Key West (EYW)
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:35, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA2856
10:20
Charlotte (CLT)

12:42
Key West (EYW)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:22, non-stop
Airbus A319 (319)
Direct Flights:
American Airlines AA3338
11:05
Charlotte (CLT)

13:25
Key West (EYW)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:20, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3351
13:05
Charlotte (CLT)

15:20
Key West (EYW)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3419
11:05
Charlotte (CLT)

13:31
Key West (EYW)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:26, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3420
13:05
Charlotte (CLT)

15:21
Key West (EYW)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:16, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3432
11:45
Charlotte (CLT)

14:05
Key West (EYW)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:20, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3512
11:05
Charlotte (CLT)

13:29
Key West (EYW)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:24, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3514
11:05
Charlotte (CLT)

13:28
Key West (EYW)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:23, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3517
13:05
Charlotte (CLT)

15:23
Key West (EYW)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:18, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3519
13:05
Charlotte (CLT)

15:22
Key West (EYW)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3752
12:28
Charlotte (CLT)

14:54
Key West (EYW)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:26, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3752
13:15
Charlotte (CLT)

15:41
Key West (EYW)
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:26, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3822
14:06
Charlotte (CLT)

16:20
Key West (EYW)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:14, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA3854
11:50
Charlotte (CLT)

14:14
Key West (EYW)
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:24, non-stop
Embraer EMB 175 (E75)
  • A domestic route departing from the Charlotte airport (CLT) and arriving at Key West airport (EYW).
  • The flight distance is 738 miles, or 1188 km.
  • The timezone of both the departure and the arrival airports is UTC-5 . Current time at both airports is (loading...).
  • For direct flights, the flight time varies between 2:03 and 2:35.
Return (EYW-CLT) flights
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