LATAM Airlines flights from Istanbul (IST) to Madrid (MAD).

Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Tue,Thu,Sat 09:55 Istanbul (IST) 13:35 Madrid (MAD) 1
LATAM Airlines LA 5661 Non-stop Airbus A321neo (32Q) 4:40 Valid until 2025-06-07
Codeshare flight, operated by Turkish Airlines.(TK 1357)
Tue,Thu 09:55 Istanbul (IST) 13:35 Madrid (MAD) 1
LATAM Airlines LA 5661 Non-stop Airbus A321 (32B) 4:40 Effective 2025-06-10 through 2025-07-03
Codeshare flight, operated by Turkish Airlines.(TK 1357)
Sat 09:55 Istanbul (IST) 13:35 Madrid (MAD) 1
LATAM Airlines LA 5661 Non-stop Airbus A321neo (32Q) 4:40 Effective 2025-06-14 through 2025-06-28
Codeshare flight, operated by Turkish Airlines.(TK 1357)
Mon,Wed,Sat,Sun 09:55 Istanbul (IST) 13:35 Madrid (MAD) 1
LATAM Airlines LA 5661 Non-stop Airbus A321neo (32Q) 4:40 Effective 2025-07-02 through 2025-09-08
Codeshare flight, operated by Turkish Airlines.(TK 1357)
Tue,Thu,Fri 09:55 Istanbul (IST) 13:35 Madrid (MAD) 1
LATAM Airlines LA 5661 Non-stop Airbus A321 (32B) 4:40 Effective 2025-07-04 through 2025-09-05
Codeshare flight, operated by Turkish Airlines.(TK 1357)
Daily 09:55 Istanbul (IST) 13:35 Madrid (MAD) 1
LATAM Airlines LA 5661 Non-stop Airbus A321neo (32Q) 4:40 Effective 2025-09-09 through 2025-10-25
Codeshare flight, operated by Turkish Airlines.(TK 1357)
Tue,Thu 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Valid until 2025-05-01
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Tue,Sat 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-300 (333) 4:35 Effective 2025-05-03 through 2025-05-17
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Thu 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-05-08 through 2025-05-15
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Tue,Thu 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-05-20 through 2025-06-05
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Sat 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-300 (333) 4:35 Effective 2025-05-24 through 2025-06-07
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Tue,Thu,Sat 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-300 (333) 4:35 Effective 2025-06-10 through 2025-06-14
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Tue,Thu 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-06-17 through 2025-07-01
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Sat 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-300 (333) 4:35 Effective 2025-06-21 through 2025-07-05
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Mon-Fri,Sun 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-07-02 through 2025-07-11
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Daily 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-07-12 through 2025-07-29
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Wed 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-300 (333) 4:35 Operates only on 2025-07-30
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Daily 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-07-31 through 2025-09-07
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Mon,Thu,Fri 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-300 (333) 4:35 Effective 2025-09-08 through 2025-10-06
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Tue,Wed,Sat,Sun 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-09-09 through 2025-10-08
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Tue-Thu,Sat,Sun 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-200 (332) 4:35 Effective 2025-10-09 through 2025-10-25
Codeshare flight, operated by Turkish Airlines.(TK 1859)
Mon,Fri 13:15 Istanbul (IST) 16:50 Madrid (MAD) 1
LATAM Airlines LA 5663 Non-stop Airbus A330-300 (333) 4:35 Effective 2025-10-10 through 2025-10-24
Codeshare flight, operated by Turkish Airlines.(TK 1859)




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LATAM Airlines flights from Istanbul (IST) to Madrid (MAD).
Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
LATAM Airlines LA5661
09:55
Istanbul (IST)

13:35
Madrid (MAD) 1
Valid until 2025-06-07
Mon
-
Tue
Wed
-
Thu
Fri
-
Sat
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1357)
Duration: 4:40, non-stop
Airbus A321neo (32Q)
LATAM Airlines LA5661
09:55
Istanbul (IST)

13:35
Madrid (MAD) 1
Effective 2025-06-10 through 2025-07-03
Mon
-
Tue
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1357)
Duration: 4:40, non-stop
Airbus A321 (32B)
LATAM Airlines LA5661
09:55
Istanbul (IST)

13:35
Madrid (MAD) 1
Effective 2025-06-14 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1357)
Duration: 4:40, non-stop
Airbus A321neo (32Q)
LATAM Airlines LA5661
09:55
Istanbul (IST)

13:35
Madrid (MAD) 1
Effective 2025-07-02 through 2025-09-08
Mon
Tue
-
Wed
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 1357)
Duration: 4:40, non-stop
Airbus A321neo (32Q)
LATAM Airlines LA5661
09:55
Istanbul (IST)

13:35
Madrid (MAD) 1
Effective 2025-07-04 through 2025-09-05
Mon
-
Tue
Wed
-
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1357)
Duration: 4:40, non-stop
Airbus A321 (32B)
LATAM Airlines LA5661
09:55
Istanbul (IST)

13:35
Madrid (MAD) 1
Effective 2025-09-09 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 1357)
Duration: 4:40, non-stop
Airbus A321neo (32Q)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Valid until 2025-05-01
Mon
-
Tue
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-05-03 through 2025-05-17
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-300 (333)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-05-08 through 2025-05-15
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-05-20 through 2025-06-05
Mon
-
Tue
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-05-24 through 2025-06-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-300 (333)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-06-10 through 2025-06-14
Mon
-
Tue
Wed
-
Thu
Fri
-
Sat
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-300 (333)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-06-17 through 2025-07-01
Mon
-
Tue
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-06-21 through 2025-07-05
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-300 (333)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-07-02 through 2025-07-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-07-12 through 2025-07-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Operates only on 2025-07-30
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-300 (333)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-07-31 through 2025-09-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-09-08 through 2025-10-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-300 (333)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-09-09 through 2025-10-08
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-10-09 through 2025-10-25
Mon
-
Tue
Wed
Thu
Fri
-
Sat
Sun
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-200 (332)
LATAM Airlines LA5663
13:15
Istanbul (IST)

16:50
Madrid (MAD) 1
Effective 2025-10-10 through 2025-10-24
Mon
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Codeshare flight, operated by Turkish Airlines. (TK 1859)
Duration: 4:35, non-stop
Airbus A330-300 (333)
  • An international route departing from Istanbul airport, Turkey (IST) and arriving at Madrid airport, Spain (MAD).
  • The flight distance is 1678 miles, or 2700 km.
  • The timezone of the departure airport is UTC+3 , and the timezone of the arrival airport is UTC+1 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 4:35 and 4:40.
All IST-MAD flights
All LATAM Airlines flights
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