Delta Air Lines flights from Minneapolis/Saint Paul (MSP) to San Diego (SAN).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 08:50 Minneapolis/Saint Paul (MSP) 1 10:50 San Diego (SAN) 2
Delta Air Lines DL 827 Non-stop Airbus A321 (321) 4:00 Effective 2026-02-12 through 2026-03-07
Daily 11:00 Minneapolis/Saint Paul (MSP) 1 13:00 San Diego (SAN) 2
Delta Air Lines DL 1683 Non-stop Airbus A321 (321) 4:00 Effective from 2026-10-06
Daily 08:50 Minneapolis/Saint Paul (MSP) 1 10:53 San Diego (SAN) 2
Delta Air Lines DL 2061 Non-stop Airbus A321 (321) 4:03 Effective from 2026-10-06
Daily 08:50 Minneapolis/Saint Paul (MSP) 1 10:48 San Diego (SAN) 2
Delta Air Lines DL 2121 Non-stop Airbus A321 (321) 3:58 Effective 2026-01-05 through 2026-02-11
Daily 08:50 Minneapolis/Saint Paul (MSP) 1 10:51 San Diego (SAN) 2
Delta Air Lines DL 2121 Non-stop Airbus A321 (321) 4:01 Effective 2026-03-08 through 2026-04-12
Daily 08:50 Minneapolis/Saint Paul (MSP) 1 10:46 San Diego (SAN) 2
Delta Air Lines DL 2121 Non-stop Airbus A321 (321) 3:56 Effective 2026-04-13 through 2026-10-05
Daily 09:25 Minneapolis/Saint Paul (MSP) 1 11:30 San Diego (SAN) 2
Delta Air Lines DL 2121 Non-stop Airbus A321 (321) 4:05 Valid until 2026-01-04
Daily 11:00 Minneapolis/Saint Paul (MSP) 1 12:55 San Diego (SAN) 2
Delta Air Lines DL 2125 Non-stop Airbus A321 (321) 3:55 Effective 2026-04-13 through 2026-10-05
Daily 11:05 Minneapolis/Saint Paul (MSP) 1 13:05 San Diego (SAN) 2
Delta Air Lines DL 2125 Non-stop Airbus A321 (321) 4:00 Valid until 2026-01-04
Daily 11:36 Minneapolis/Saint Paul (MSP) 1 13:37 San Diego (SAN) 2
Delta Air Lines DL 2125 Non-stop Airbus A321 (321) 4:01 Effective 2026-03-08 through 2026-04-12
Daily 11:45 Minneapolis/Saint Paul (MSP) 1 13:48 San Diego (SAN) 2
Delta Air Lines DL 2125 Non-stop Airbus A321 (321) 4:03 Effective 2026-01-05 through 2026-03-07
Daily 18:25 Minneapolis/Saint Paul (MSP) 1 20:21 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Airbus A321 (321) 3:56 Effective 2026-04-13 through 2026-10-05
Daily 18:25 Minneapolis/Saint Paul (MSP) 1 20:25 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Airbus A321 (321) 4:00 Effective from 2026-10-06
Mon-Wed 18:45 Minneapolis/Saint Paul (MSP) 1 20:49 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Boeing 737-900 (739) 4:04 Effective 2026-01-19 through 2026-01-21
Daily 18:45 Minneapolis/Saint Paul (MSP) 1 20:48 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Airbus A321 (321) 4:03 Effective 2026-01-22 through 2026-02-11
Daily 18:48 Minneapolis/Saint Paul (MSP) 1 20:51 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Airbus A321 (321) 4:03 Effective 2026-01-05 through 2026-01-18
Daily 18:50 Minneapolis/Saint Paul (MSP) 1 20:53 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Airbus A321 (321) 4:03 Effective 2026-02-12 through 2026-03-07
Daily 18:50 Minneapolis/Saint Paul (MSP) 1 20:52 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Airbus A321 (321) 4:02 Effective 2026-03-08 through 2026-04-12
Daily 19:01 Minneapolis/Saint Paul (MSP) 1 21:03 San Diego (SAN) 2
Delta Air Lines DL 2145 Non-stop Airbus A321 (321) 4:02 Valid until 2026-01-04
Mon-Fri,Sun 21:25 Minneapolis/Saint Paul (MSP) 1 23:19 San Diego (SAN) 2
Delta Air Lines DL 2146 Non-stop Airbus A321 (321) 3:54 Effective 2026-04-13 through 2026-05-22
Mon-Fri,Sun 21:25 Minneapolis/Saint Paul (MSP) 1 23:19 San Diego (SAN) 2
Delta Air Lines DL 2146 Non-stop Airbus A321 (321) 3:54 Effective 2026-05-25 through 2026-09-04
Mon-Fri,Sun 21:25 Minneapolis/Saint Paul (MSP) 1 23:19 San Diego (SAN) 2
Delta Air Lines DL 2146 Non-stop Airbus A321 (321) 3:54 Effective 2026-09-07 through 2026-10-05
Mon-Fri,Sun 21:25 Minneapolis/Saint Paul (MSP) 1 23:25 San Diego (SAN) 2
Delta Air Lines DL 2146 Non-stop Airbus A321 (321) 4:00 Effective from 2026-10-06
Mon-Fri,Sun 21:40 Minneapolis/Saint Paul (MSP) 1 23:40 San Diego (SAN) 2
Delta Air Lines DL 2146 Non-stop Airbus A321 (321) 4:00 Effective 2026-03-08 through 2026-04-12
Mon,Tue,Fri-Sun 21:59 Minneapolis/Saint Paul (MSP) 1 23:55 San Diego (SAN) 2
Delta Air Lines DL 2146 Non-stop Airbus A321 (321) 3:56 Valid until 2026-01-04




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Delta Air Lines flights from Minneapolis/Saint Paul (MSP) to San Diego (SAN).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Delta Air Lines DL827
08:50
Minneapolis/Saint Paul (MSP) 1

10:50
San Diego (SAN) 2
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:00, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL1683
11:00
Minneapolis/Saint Paul (MSP) 1

13:00
San Diego (SAN) 2
Effective from 2026-10-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:00, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2061
08:50
Minneapolis/Saint Paul (MSP) 1

10:53
San Diego (SAN) 2
Effective from 2026-10-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:03, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2121
08:50
Minneapolis/Saint Paul (MSP) 1

10:48
San Diego (SAN) 2
Effective 2026-01-05 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:58, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2121
08:50
Minneapolis/Saint Paul (MSP) 1

10:51
San Diego (SAN) 2
Effective 2026-03-08 through 2026-04-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:01, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2121
08:50
Minneapolis/Saint Paul (MSP) 1

10:46
San Diego (SAN) 2
Effective 2026-04-13 through 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:56, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2121
09:25
Minneapolis/Saint Paul (MSP) 1

11:30
San Diego (SAN) 2
Valid until 2026-01-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:05, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2125
11:00
Minneapolis/Saint Paul (MSP) 1

12:55
San Diego (SAN) 2
Effective 2026-04-13 through 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:55, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2125
11:05
Minneapolis/Saint Paul (MSP) 1

13:05
San Diego (SAN) 2
Valid until 2026-01-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:00, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2125
11:36
Minneapolis/Saint Paul (MSP) 1

13:37
San Diego (SAN) 2
Effective 2026-03-08 through 2026-04-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:01, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2125
11:45
Minneapolis/Saint Paul (MSP) 1

13:48
San Diego (SAN) 2
Effective 2026-01-05 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:03, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2145
18:25
Minneapolis/Saint Paul (MSP) 1

20:21
San Diego (SAN) 2
Effective 2026-04-13 through 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:56, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2145
18:25
Minneapolis/Saint Paul (MSP) 1

20:25
San Diego (SAN) 2
Effective from 2026-10-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:00, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2145
18:45
Minneapolis/Saint Paul (MSP) 1

20:49
San Diego (SAN) 2
Effective 2026-01-19 through 2026-01-21
Mon
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 4:04, non-stop
Boeing 737-900 (739)
Direct Flights:
Delta Air Lines DL2145
18:45
Minneapolis/Saint Paul (MSP) 1

20:48
San Diego (SAN) 2
Effective 2026-01-22 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:03, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2145
18:48
Minneapolis/Saint Paul (MSP) 1

20:51
San Diego (SAN) 2
Effective 2026-01-05 through 2026-01-18
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:03, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2145
18:50
Minneapolis/Saint Paul (MSP) 1

20:53
San Diego (SAN) 2
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:03, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2145
18:50
Minneapolis/Saint Paul (MSP) 1

20:52
San Diego (SAN) 2
Effective 2026-03-08 through 2026-04-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:02, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2145
19:01
Minneapolis/Saint Paul (MSP) 1

21:03
San Diego (SAN) 2
Valid until 2026-01-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:02, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2146
21:25
Minneapolis/Saint Paul (MSP) 1

23:19
San Diego (SAN) 2
Effective 2026-04-13 through 2026-05-22
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 3:54, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2146
21:25
Minneapolis/Saint Paul (MSP) 1

23:19
San Diego (SAN) 2
Effective 2026-05-25 through 2026-09-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 3:54, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2146
21:25
Minneapolis/Saint Paul (MSP) 1

23:19
San Diego (SAN) 2
Effective 2026-09-07 through 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 3:54, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2146
21:25
Minneapolis/Saint Paul (MSP) 1

23:25
San Diego (SAN) 2
Effective from 2026-10-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 4:00, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2146
21:40
Minneapolis/Saint Paul (MSP) 1

23:40
San Diego (SAN) 2
Effective 2026-03-08 through 2026-04-12
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 4:00, non-stop
Airbus A321 (321)
Direct Flights:
Delta Air Lines DL2146
21:59
Minneapolis/Saint Paul (MSP) 1

23:55
San Diego (SAN) 2
Valid until 2026-01-04
Mon
Tue
Wed
-
Thu
-
Fri
Sat
Sun
Duration: 3:56, non-stop
Airbus A321 (321)
  • A domestic route departing from the Minneapolis/Saint Paul airport (MSP) and arriving at San Diego airport (SAN).
  • The flight distance is 1529 miles, or 2461 km.
  • The timezone of the departure airport is UTC-6 , and the timezone of the arrival airport is UTC-8 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 3:54 and 4:05.
All MSP-SAN flights
All Delta Air Lines flights
Return (SAN-MSP) flights
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