American Airlines flights from Philadelphia (PHL) to Des Moines (DSM).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 18:35 Philadelphia (PHL) 20:34 Des Moines (DSM)
American Airlines AA 4416 Non-stop Embraer EMB 175 (E75) 2:59 Effective 2026-07-02 through 2026-08-04
Daily 10:25 Philadelphia (PHL) 12:18 Des Moines (DSM)
American Airlines AA 4599 Non-stop Embraer EMB 175 (E75) 2:53 Effective 2026-09-09 through 2026-10-04
Daily 10:25 Philadelphia (PHL) F 12:19 Des Moines (DSM)
American Airlines AA 5082 Non-stop Canadair CRJ 900 (CR9) 2:54 Effective from 2026-10-05
Daily 10:25 Philadelphia (PHL) F 12:14 Des Moines (DSM)
American Airlines AA 5123 Non-stop Canadair CRJ 900 (CR9) 2:49 Effective 2026-08-05 through 2026-09-08
Daily 10:25 Philadelphia (PHL) F 12:14 Des Moines (DSM)
American Airlines AA 5165 Non-stop Canadair CRJ 700 (CR7) 2:49 Effective 2026-05-21 through 2026-07-01
Daily 10:25 Philadelphia (PHL) F 12:21 Des Moines (DSM)
American Airlines AA 5172 Non-stop Canadair CRJ 900 (CR9) 2:56 Effective 2026-07-02 through 2026-08-04
Daily 18:35 Philadelphia (PHL) F 20:34 Des Moines (DSM)
American Airlines AA 5478 Non-stop Canadair CRJ 700 (CR7) 2:59 Effective 2026-05-21 through 2026-07-01
Daily 18:35 Philadelphia (PHL) F 20:46 Des Moines (DSM)
American Airlines AA 5478 Non-stop Canadair CRJ 700 (CR7) 3:11 Effective 2026-09-09 through 2026-10-04
Daily 18:35 Philadelphia (PHL) F 20:29 Des Moines (DSM)
American Airlines AA 5478 Non-stop Canadair CRJ 900 (CR9) 2:54 Effective from 2026-10-05
Daily 19:39 Philadelphia (PHL) F 21:44 Des Moines (DSM)
American Airlines AA 5478 Non-stop Canadair CRJ 900 (CR9) 3:05 Effective 2026-08-05 through 2026-09-08




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American Airlines flights from Philadelphia (PHL) to Des Moines (DSM).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4416
18:35
Philadelphia (PHL)

20:34
Des Moines (DSM)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:59, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4599
10:25
Philadelphia (PHL)

12:18
Des Moines (DSM)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:53, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA5082
10:25
Philadelphia (PHL) F

12:19
Des Moines (DSM)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:54, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5123
10:25
Philadelphia (PHL) F

12:14
Des Moines (DSM)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:49, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5165
10:25
Philadelphia (PHL) F

12:14
Des Moines (DSM)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:49, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5172
10:25
Philadelphia (PHL) F

12:21
Des Moines (DSM)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:56, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5478
18:35
Philadelphia (PHL) F

20:34
Des Moines (DSM)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:59, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5478
18:35
Philadelphia (PHL) F

20:46
Des Moines (DSM)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:11, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5478
18:35
Philadelphia (PHL) F

20:29
Des Moines (DSM)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:54, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5478
19:39
Philadelphia (PHL) F

21:44
Des Moines (DSM)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:05, non-stop
Canadair CRJ 900 (CR9)
  • A domestic route departing from the Philadelphia airport (PHL) and arriving at Des Moines airport (DSM).
  • The flight distance is 969 miles, or 1559 km.
  • The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 2:49 and 3:11.
All PHL-DSM flights
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