American Airlines flights from Chicago O'Hare (ORD) to Des Moines (DSM).

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 18:35 Chicago O'Hare (ORD) 3 20:02 Des Moines (DSM)
American Airlines AA 856 Non-stop Airbus A319 (319) 1:27 Effective 2026-05-21 through 2026-07-01
Daily 18:35 Chicago O'Hare (ORD) 3 20:00 Des Moines (DSM)
American Airlines AA 856 Non-stop Airbus A319 (319) 1:25 Effective 2026-07-02 through 2026-08-04
Daily 22:05 Chicago O'Hare (ORD) 3 23:28 Des Moines (DSM)
American Airlines AA 2126 Non-stop Airbus A319 (319) 1:23 Effective 2026-09-09 through 2026-10-04
Daily 18:35 Chicago O'Hare (ORD) 3 20:11 Des Moines (DSM)
American Airlines AA 2424 Non-stop Boeing 737-800 (738) 1:36 Effective from 2026-10-05
Daily 22:00 Chicago O'Hare (ORD) 3 23:26 Des Moines (DSM)
American Airlines AA 3365 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2026-08-05 through 2026-09-08
Daily 11:25 Chicago O'Hare (ORD) 3 12:52 Des Moines (DSM)
American Airlines AA 3413 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:27 Effective 2026-08-05 through 2026-09-08
Daily 11:42 Chicago O'Hare (ORD) 3 13:10 Des Moines (DSM)
American Airlines AA 3444 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:28 Effective 2026-03-08 through 2026-04-06
Mon,Tue,Thu-Sun 09:40 Chicago O'Hare (ORD) 3 11:12 Des Moines (DSM)
American Airlines AA 3469 Non-stop Embraer EMB 175 (E75) 1:32 Effective 2026-01-06 through 2026-01-17
Wed 09:40 Chicago O'Hare (ORD) 3 11:12 Des Moines (DSM)
American Airlines AA 3469 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:32 Effective 2026-01-07 through 2026-02-11
Mon,Tue,Thu-Sun 09:40 Chicago O'Hare (ORD) 3 11:12 Des Moines (DSM)
American Airlines AA 3469 Non-stop Embraer EMB 175 (E75) 1:32 Effective 2026-01-19 through 2026-02-06
Mon,Tue,Sun 09:40 Chicago O'Hare (ORD) 3 11:12 Des Moines (DSM)
American Airlines AA 3469 Non-stop Embraer EMB 175 (E75) 1:32 Effective 2026-02-08 through 2026-02-10
Sat 14:50 Chicago O'Hare (ORD) 3 16:24 Des Moines (DSM)
American Airlines AA 3485 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:34 Operates only on 2026-01-17
Daily 19:35 Chicago O'Hare (ORD) 3 21:04 Des Moines (DSM)
American Airlines AA 3485 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:29 Effective 2026-01-06 through 2026-01-16
Daily 19:35 Chicago O'Hare (ORD) 3 21:04 Des Moines (DSM)
American Airlines AA 3485 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:29 Effective 2026-01-18 through 2026-02-10
Sat 16:25 Chicago O'Hare (ORD) 3 17:51 Des Moines (DSM)
American Airlines AA 3653 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:26 Operates only on 2026-02-14
Sat 16:54 Chicago O'Hare (ORD) 3 18:22 Des Moines (DSM)
American Airlines AA 3653 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:28 Effective 2026-03-14 through 2026-04-04
Sat 17:01 Chicago O'Hare (ORD) 3 18:27 Des Moines (DSM)
American Airlines AA 3653 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:26 Effective 2026-02-21 through 2026-03-07
Sat 11:25 Chicago O'Hare (ORD) 3 12:54 Des Moines (DSM)
American Airlines AA 3703 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:29 Valid until 2026-01-03
Mon,Wed-Fri,Sun 11:30 Chicago O'Hare (ORD) 3 12:54 Des Moines (DSM)
American Airlines AA 3703 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:24 Valid until 2026-01-05
Mon,Thu,Sun 22:00 Chicago O'Hare (ORD) 3 23:30 Des Moines (DSM)
American Airlines AA 3921 Non-stop Embraer EMB 175 (E75) 1:30 Valid until 2026-01-05
Mon,Tue,Thu,Fri,Sun 13:29 Chicago O'Hare (ORD) 3 14:53 Des Moines (DSM)
American Airlines AA 4103 Non-stop Embraer EMB 175 (E75) 1:24 Valid until 2026-01-05
Sun 11:45 Chicago O'Hare (ORD) 3 13:17 Des Moines (DSM)
American Airlines AA 4136 Non-stop Embraer EMB 175 (E75) 1:32 Operates only on 2026-01-18
Daily 18:30 Chicago O'Hare (ORD) 3 20:01 Des Moines (DSM)
American Airlines AA 4402 Non-stop Embraer EMB 175 (E75) 1:31 Effective 2026-09-09 through 2026-10-04
Daily 09:40 Chicago O'Hare (ORD) 3 11:07 Des Moines (DSM)
American Airlines AA 4431 Non-stop Embraer EMB 175 (E75) 1:27 Effective 2026-04-07 through 2026-05-20
Daily 16:40 Chicago O'Hare (ORD) 3 18:04 Des Moines (DSM)
American Airlines AA 4432 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2026-04-07 through 2026-05-20
Daily 22:00 Chicago O'Hare (ORD) 3 23:22 Des Moines (DSM)
American Airlines AA 4442 Non-stop Embraer EMB 175 (E75) 1:22 Effective 2026-05-21 through 2026-08-04
Daily 20:20 Chicago O'Hare (ORD) 3 21:44 Des Moines (DSM)
American Airlines AA 4450 Non-stop Embraer EMB 175 (E75) 1:24 Effective from 2026-10-05
Sun 16:28 Chicago O'Hare (ORD) 3 17:57 Des Moines (DSM)
American Airlines AA 4753 Non-stop Embraer EMB 175 (E75) 1:29 Operates only on 2026-02-15
Sat 19:30 Chicago O'Hare (ORD) 3 20:57 Des Moines (DSM)
American Airlines AA 4805 Non-stop Embraer EMB 175 (E75) 1:27 Operates only on 2026-02-14
Sun 19:34 Chicago O'Hare (ORD) 3 21:01 Des Moines (DSM)
American Airlines AA 4805 Non-stop Embraer EMB 175 (E75) 1:27 Operates only on 2026-02-15
Thu,Fri 20:59 Chicago O'Hare (ORD) 3 22:25 Des Moines (DSM)
American Airlines AA 4805 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2026-02-12 through 2026-02-13
Daily 20:59 Chicago O'Hare (ORD) 3 22:33 Des Moines (DSM)
American Airlines AA 4805 Non-stop Embraer EMB 175 (E75) 1:34 Effective 2026-03-08 through 2026-04-06
Daily 21:00 Chicago O'Hare (ORD) 3 22:26 Des Moines (DSM)
American Airlines AA 4805 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2026-02-16 through 2026-03-07
Fri,Sat 22:14 Chicago O'Hare (ORD) 3 23:51 Des Moines (DSM)
American Airlines AA 4805 Non-stop Embraer EMB 175 (E75) 1:37 Valid until 2026-01-03
Daily 08:04 Chicago O'Hare (ORD) 3 09:39 Des Moines (DSM)
American Airlines AA 4899 Non-stop Canadair CRJ 700 (CR7) 1:35 Effective 2026-02-12 through 2026-03-07
Daily 11:40 Chicago O'Hare (ORD) 3 13:06 Des Moines (DSM)
American Airlines AA 4903 Non-stop Canadair CRJ 700 (CR7) 1:26 Effective from 2026-10-05
Daily 14:50 Chicago O'Hare (ORD) 3 16:20 Des Moines (DSM)
American Airlines AA 4904 Non-stop Canadair CRJ 700 (CR7) 1:30 Effective from 2026-10-05
Daily 22:00 Chicago O'Hare (ORD) 3 23:26 Des Moines (DSM)
American Airlines AA 4924 Non-stop Canadair CRJ 700 (CR7) 1:26 Effective 2026-04-07 through 2026-05-20
Daily 14:50 Chicago O'Hare (ORD) 3 16:22 Des Moines (DSM)
American Airlines AA 4928 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-09-09 through 2026-10-04
Daily 06:40 Chicago O'Hare (ORD) 3 08:07 Des Moines (DSM)
American Airlines AA 4932 Non-stop Canadair CRJ 700 (CR7) 1:27 Effective 2026-09-09 through 2026-10-04
Daily 11:40 Chicago O'Hare (ORD) 3 13:04 Des Moines (DSM)
American Airlines AA 4933 Non-stop Canadair CRJ 700 (CR7) 1:24 Effective 2026-09-09 through 2026-10-04
Daily 07:00 Chicago O'Hare (ORD) 3 08:30 Des Moines (DSM)
American Airlines AA 4955 Non-stop Canadair CRJ 700 (CR7) 1:30 Effective 2026-08-05 through 2026-09-08
Daily 13:43 Chicago O'Hare (ORD) 3 15:08 Des Moines (DSM)
American Airlines AA 4965 Non-stop Canadair CRJ 700 (CR7) 1:25 Effective 2026-08-05 through 2026-09-08
Daily 06:40 Chicago O'Hare (ORD) 3 08:13 Des Moines (DSM)
American Airlines AA 4969 Non-stop Canadair CRJ 700 (CR7) 1:33 Effective 2026-05-21 through 2026-07-01
Daily 11:40 Chicago O'Hare (ORD) 3 13:04 Des Moines (DSM)
American Airlines AA 4972 Non-stop Canadair CRJ 700 (CR7) 1:24 Effective 2026-05-21 through 2026-07-01
Daily 14:50 Chicago O'Hare (ORD) 3 16:14 Des Moines (DSM)
American Airlines AA 4973 Non-stop Canadair CRJ 700 (CR7) 1:24 Effective 2026-05-21 through 2026-07-01
Daily 08:00 Chicago O'Hare (ORD) 3 09:23 Des Moines (DSM)
American Airlines AA 4978 Non-stop Canadair CRJ 700 (CR7) 1:23 Effective 2026-07-02 through 2026-08-04
Daily 11:40 Chicago O'Hare (ORD) 3 13:06 Des Moines (DSM)
American Airlines AA 4985 Non-stop Canadair CRJ 700 (CR7) 1:26 Effective 2026-07-02 through 2026-08-04
Daily 14:50 Chicago O'Hare (ORD) 3 16:14 Des Moines (DSM)
American Airlines AA 4986 Non-stop Canadair CRJ 700 (CR7) 1:24 Effective 2026-07-02 through 2026-08-04
Daily 14:50 Chicago O'Hare (ORD) 3 16:24 Des Moines (DSM)
American Airlines AA 4997 Non-stop Canadair CRJ 700 (CR7) 1:34 Effective 2026-01-06 through 2026-01-16
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American Airlines flights from Chicago O'Hare (ORD) to Des Moines (DSM).
Select flight date:
FLIGHT SCHEDULE
Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:27, non-stop
Airbus A319 (319)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:25, non-stop
Airbus A319 (319)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:23, non-stop
Airbus A319 (319)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Boeing 737-800 (738)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:27, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:28, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective 2026-01-06 through 2026-01-17
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 1:32, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-01-07 through 2026-02-11
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:32, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective 2026-01-19 through 2026-02-06
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 1:32, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-02-08 through 2026-02-10
Mon
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:32, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Operates only on 2026-01-17
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:34, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective 2026-01-06 through 2026-01-16
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:29, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective 2026-01-18 through 2026-02-10
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:29, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Operates only on 2026-02-14
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:26, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:28, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Effective 2026-02-21 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:26, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:29, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
-
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:24, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
Duration: 1:30, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Operates only on 2026-01-18
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:32, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:31, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:27, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-05-21 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:22, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Operates only on 2026-02-15
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:29, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Operates only on 2026-02-14
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:27, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Operates only on 2026-02-15
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:27, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-02-12 through 2026-02-13
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 1:26, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:34, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-02-16 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
Sun
-
Duration: 1:37, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:35, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:30, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:27, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:30, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:25, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:33, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:23, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-01-06 through 2026-01-16
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:34, non-stop
Canadair CRJ 700 (CR7)
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  • A domestic route departing from the Chicago O'Hare airport (ORD) and arriving at Des Moines airport (DSM).
  • The flight distance is 298 miles, or 479 km.
  • The timezone of both the departure and the arrival airports is UTC-6 . Current time at both airports is (loading...).
  • For direct flights, the flight time varies between 1:22 and 1:37.