Alaska Airlines flights from Ronald Reagan Washington (DCA) to Greenville/Spartanburg (GSP).

Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Sat 17:00 Ronald Reagan Washington (DCA) 2 18:43 Greenville/Spartanburg (GSP)
Alaska Airlines AS 4291 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-14 through 2026-03-07
Codeshare flight, operated by American Airlines.(AA 5094)
Mon-Fri,Sun 17:31 Ronald Reagan Washington (DCA) 2 19:16 Greenville/Spartanburg (GSP)
Alaska Airlines AS 4291 Non-stop Canadair CRJ 900 (CR9) 1:45 Effective 2026-02-12 through 2026-03-06
Codeshare flight, operated by American Airlines.(AA 5094)
Sat 16:59 Ronald Reagan Washington (DCA) 2 18:39 Greenville/Spartanburg (GSP)
Alaska Airlines AS 4299 Non-stop Canadair CRJ 700 (CR7) 1:40 Valid until 2026-01-03
Codeshare flight, operated by American Airlines.(AA 5112)
Daily 17:08 Ronald Reagan Washington (DCA) 2 18:40 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 5107)
Daily 17:12 Ronald Reagan Washington (DCA) 2 18:54 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 5208)
Daily 17:15 Ronald Reagan Washington (DCA) 2 18:53 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:38 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 5140)
Mon-Fri,Sun 17:26 Ronald Reagan Washington (DCA) 2 19:12 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:46 Effective 2026-01-06 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 5563)
Mon-Fri,Sun 17:26 Ronald Reagan Washington (DCA) 2 19:07 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 900 (CR9) 1:41 Effective 2026-03-08 through 2026-04-06
Codeshare flight, operated by American Airlines.(AA 5246)
Daily 17:29 Ronald Reagan Washington (DCA) 2 19:06 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:37 Effective 2026-05-21 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 5208)
Daily 17:34 Ronald Reagan Washington (DCA) 2 19:10 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:36 Effective 2026-04-07 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 5247)
Daily 17:36 Ronald Reagan Washington (DCA) 2 19:14 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:38 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 5093)
Sat 17:39 Ronald Reagan Washington (DCA) 2 19:27 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:48 Effective 2026-03-14 through 2026-04-04
Codeshare flight, operated by American Airlines.(AA 5246)
Sat 19:20 Ronald Reagan Washington (DCA) 2 21:05 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-01-10 through 2026-02-07
Codeshare flight, operated by American Airlines.(AA 5576)
Mon,Tue,Thu,Fri,Sun 20:56 Ronald Reagan Washington (DCA) 2 22:35 Greenville/Spartanburg (GSP)
Alaska Airlines AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:39 Valid until 2026-01-05
Codeshare flight, operated by American Airlines.(AA 5576)




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Alaska Airlines flights from Ronald Reagan Washington (DCA) to Greenville/Spartanburg (GSP).
Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS4291
17:00
Ronald Reagan Washington (DCA) 2

18:43
Greenville/Spartanburg (GSP)
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5094)
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4291
17:31
Ronald Reagan Washington (DCA) 2

19:16
Greenville/Spartanburg (GSP)
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5094)
Duration: 1:45, non-stop
Canadair CRJ 900 (CR9)
Direct Codeshare Flights:
Alaska Airlines AS4299
16:59
Ronald Reagan Washington (DCA) 2

18:39
Greenville/Spartanburg (GSP)
Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5112)
Duration: 1:40, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:08
Ronald Reagan Washington (DCA) 2

18:40
Greenville/Spartanburg (GSP)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5107)
Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:12
Ronald Reagan Washington (DCA) 2

18:54
Greenville/Spartanburg (GSP)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5208)
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:15
Ronald Reagan Washington (DCA) 2

18:53
Greenville/Spartanburg (GSP)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5140)
Duration: 1:38, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:26
Ronald Reagan Washington (DCA) 2

19:12
Greenville/Spartanburg (GSP)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5563)
Duration: 1:46, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:26
Ronald Reagan Washington (DCA) 2

19:07
Greenville/Spartanburg (GSP)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5246)
Duration: 1:41, non-stop
Canadair CRJ 900 (CR9)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:29
Ronald Reagan Washington (DCA) 2

19:06
Greenville/Spartanburg (GSP)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5208)
Duration: 1:37, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:34
Ronald Reagan Washington (DCA) 2

19:10
Greenville/Spartanburg (GSP)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5247)
Duration: 1:36, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:36
Ronald Reagan Washington (DCA) 2

19:14
Greenville/Spartanburg (GSP)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5093)
Duration: 1:38, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
17:39
Ronald Reagan Washington (DCA) 2

19:27
Greenville/Spartanburg (GSP)
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5246)
Duration: 1:48, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
19:20
Ronald Reagan Washington (DCA) 2

21:05
Greenville/Spartanburg (GSP)
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5576)
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6221
20:56
Ronald Reagan Washington (DCA) 2

22:35
Greenville/Spartanburg (GSP)
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5576)
Duration: 1:39, non-stop
Canadair CRJ 700 (CR7)
  • A domestic route departing from the Ronald Reagan Washington airport (DCA) and arriving at Greenville/Spartanburg airport (GSP).
  • The flight distance is 395 miles, or 635 km.
  • The timezone of both the departure and the arrival airports is UTC-5 . Current time at both airports is (loading...).
  • For direct flights, the flight time varies between 1:32 and 1:48.
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