United Airlines flight UA 5381: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Tue 10:50 Chicago O'Hare (ORD) 2 13:23 Dayton (DAY)
UA 5381 Non-stop Embraer EMB 175 (E7W) 1:33 Effective 2026-02-03 through 2026-02-10
Daily 13:56 Detroit (DTW) E 14:39 Chicago O'Hare (ORD) 2
UA 5381 Non-stop Embraer EMB 175 (E7W) 1:43 Valid until 2026-01-05
Daily 14:10 Detroit (DTW) E 14:40 Chicago O'Hare (ORD) 2
UA 5381 Non-stop Embraer EMB 175 (E7W) 1:30 Effective 2026-03-05 through 2026-03-28
Daily 14:10 Detroit (DTW) E 14:45 Chicago O'Hare (ORD) 2
UA 5381 Non-stop Embraer EMB 175 (E7W) 1:35 Effective 2026-03-29 through 2026-04-29
Daily 14:15 Detroit (DTW) E 14:36 Chicago O'Hare (ORD) 2
UA 5381 Non-stop Embraer EMB 175 (E7W) 1:21 Effective from 2026-04-30
Daily 14:20 Detroit (DTW) E 14:50 Chicago O'Hare (ORD) 2
UA 5381 Non-stop Embraer EMB 175 (E7W) 1:30 Effective 2026-02-12 through 2026-03-04
Wed 16:35 San Francisco (SFO) 3 19:31 Salt Lake City (SLC)
UA 5381 Non-stop Embraer EMB 175 (E7W) 1:56 Effective 2026-01-07 through 2026-02-11
This flight number is listed as serving the following routes:


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United Airlines flight UA 5381: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
United Airlines UA5381
10:50
Chicago O'Hare (ORD) 2

13:23
Dayton (DAY)
Effective 2026-02-03 through 2026-02-10
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:33, non-stop
Embraer EMB 175 (E7W)
Direct Flights:
United Airlines UA5381
13:56
Detroit (DTW) E

14:39
Chicago O'Hare (ORD) 2
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Embraer EMB 175 (E7W)
Direct Flights:
United Airlines UA5381
14:10
Detroit (DTW) E

14:40
Chicago O'Hare (ORD) 2
Effective 2026-03-05 through 2026-03-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:30, non-stop
Embraer EMB 175 (E7W)
Direct Flights:
United Airlines UA5381
14:10
Detroit (DTW) E

14:45
Chicago O'Hare (ORD) 2
Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:35, non-stop
Embraer EMB 175 (E7W)
Direct Flights:
United Airlines UA5381
14:15
Detroit (DTW) E

14:36
Chicago O'Hare (ORD) 2
Effective from 2026-04-30
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:21, non-stop
Embraer EMB 175 (E7W)
Direct Flights:
United Airlines UA5381
14:20
Detroit (DTW) E

14:50
Chicago O'Hare (ORD) 2
Effective 2026-02-12 through 2026-03-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:30, non-stop
Embraer EMB 175 (E7W)
Direct Flights:
United Airlines UA5381
16:35
San Francisco (SFO) 3

19:31
Salt Lake City (SLC)
Effective 2026-01-07 through 2026-02-11
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:56, non-stop
Embraer EMB 175 (E7W)
This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Dayton (DAY)
  • Detroit (DTW) - Chicago O'Hare (ORD)
  • San Francisco (SFO) - Salt Lake City (SLC)
All United Airlines flights
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