Delta Air Lines flight DL 5643: Multiple routes

FLIGHT SCHEDULE
Direct Flights:
Daily 08:30 New York LaGuardia (LGA) C 10:55 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:25 Effective 2026-04-13 through 2026-10-05
Daily 08:30 New York LaGuardia (LGA) C 11:03 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:33 Effective from 2026-10-06
Mon-Fri,Sun 08:54 New York LaGuardia (LGA) C 11:23 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:29 Effective 2026-03-08 through 2026-04-12
Sun 08:55 Louisville (SDF) 11:13 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:18 Effective 2026-01-25 through 2026-02-08
Sun 10:55 Louisville (SDF) 13:12 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:17 Effective 2026-01-11 through 2026-01-18
Sat 11:10 New York LaGuardia (LGA) C 13:37 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:27 Effective 2026-03-14 through 2026-04-11
Sat 11:15 New York LaGuardia (LGA) C 13:54 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:39 Effective 2026-01-24 through 2026-02-07
Sat 11:15 New York LaGuardia (LGA) C 13:52 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2026-02-14 through 2026-03-07
Sat 11:17 New York LaGuardia (LGA) C 13:56 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:39 Effective 2026-01-10 through 2026-01-17
Mon-Fri,Sun 11:45 Louisville (SDF) 13:59 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:14 Effective 2026-04-13 through 2026-08-14
Daily 11:45 Louisville (SDF) 13:59 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:14 Effective 2026-08-15 through 2026-10-05
Mon-Fri,Sun 11:45 Louisville (SDF) 13:56 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:11 Effective from 2026-10-06
Sat 11:45 Louisville (SDF) 13:59 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:14 Effective from 2026-10-10
Mon-Fri,Sun 12:03 Louisville (SDF) 14:10 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:07 Effective 2026-03-08 through 2026-04-12
Sat 13:00 Louisville (SDF) 15:14 New York LaGuardia (LGA) C DL 5643 Non-stop Embraer EMB 175 (E75) 2:14 Effective 2026-04-18 through 2026-08-08
Mon,Tue,Fri-Sun 17:15 New York LaGuardia (LGA) C 19:50 Louisville (SDF) DL 5643 Non-stop Embraer EMB 175 (E75) 2:35 Valid until 2026-01-03
Sun 17:15 New York LaGuardia (LGA) C 19:50 Louisville (SDF) DL 5643 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:35 Operates only on 2026-01-04

This flight number is listed as serving the following routes:

New York LaGuardia (LGA) - Louisville (SDF)

All Delta Air Lines flights

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Delta Air Lines flight DL 5643: Multiple routes

FLIGHT SCHEDULE

Direct Flights:

Delta Air Lines DL5643

08:30

New York LaGuardia (LGA) C

10:55

Louisville (SDF)

Effective 2026-04-13 through 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:25, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

08:30

New York LaGuardia (LGA) C

11:03

Louisville (SDF)

Effective from 2026-10-06

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:33, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

08:54

New York LaGuardia (LGA) C

11:23

Louisville (SDF)

Effective 2026-03-08 through 2026-04-12

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:29, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

08:55

Louisville (SDF)

11:13

New York LaGuardia (LGA) C

Effective 2026-01-25 through 2026-02-08

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

10:55

Louisville (SDF)

13:12

New York LaGuardia (LGA) C

Effective 2026-01-11 through 2026-01-18

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:17, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:10

New York LaGuardia (LGA) C

13:37

Louisville (SDF)

Effective 2026-03-14 through 2026-04-11

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:27, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:15

New York LaGuardia (LGA) C

13:54

Louisville (SDF)

Effective 2026-01-24 through 2026-02-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:39, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:15

New York LaGuardia (LGA) C

13:52

Louisville (SDF)

Effective 2026-02-14 through 2026-03-07

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:37, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:17

New York LaGuardia (LGA) C

13:56

Louisville (SDF)

Effective 2026-01-10 through 2026-01-17

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:39, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:45

Louisville (SDF)

13:59

New York LaGuardia (LGA) C

Effective 2026-04-13 through 2026-08-14

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:14, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:45

Louisville (SDF)

13:59

New York LaGuardia (LGA) C

Effective 2026-08-15 through 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:14, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:45

Louisville (SDF)

13:56

New York LaGuardia (LGA) C

Effective from 2026-10-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:11, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

11:45

Louisville (SDF)

13:59

New York LaGuardia (LGA) C

Effective from 2026-10-10

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:14, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

12:03

Louisville (SDF)

14:10

New York LaGuardia (LGA) C

Effective 2026-03-08 through 2026-04-12

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 2:07, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

13:00

Louisville (SDF)

15:14

New York LaGuardia (LGA) C

Effective 2026-04-18 through 2026-08-08

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:14, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

17:15

New York LaGuardia (LGA) C

19:50

Louisville (SDF)

Valid until 2026-01-03

Mon

Tue

Wed
-

Thu
-

Fri

Sat

Sun

Duration: 2:35, non-stop
Embraer EMB 175 (E75)

Direct Flights:

Delta Air Lines DL5643

17:15

New York LaGuardia (LGA) C

19:50

Louisville (SDF)

Operates only on 2026-01-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:35, non-stop
Embraer EMB 170 / EMB 175 (E70)

This flight number is listed as serving the following routes:

New York LaGuardia (LGA) - Louisville (SDF)

All Delta Air Lines flights

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