American Airlines flight AA 5278: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 06:40 Lexington (LEX) 08:20 Charlotte (CLT)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 1:40 Effective from 2026-10-05
Daily 06:41 Lexington (LEX) 08:10 Charlotte (CLT)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 1:29 Effective 2026-08-05 through 2026-09-08
Daily 06:52 Lexington (LEX) 08:20 Charlotte (CLT)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 1:28 Effective 2026-04-07 through 2026-05-20
Daily 08:20 Ronald Reagan Washington (DCA) 2 09:54 Memphis (MEM)
AA 5278 Non-stop Canadair CRJ 700 (CR7) 2:34 Effective 2026-05-21 through 2026-07-01
Daily 09:00 Charlotte (CLT) 11:29 Manchester (MHT)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:29 Effective 2026-07-02 through 2026-08-04
Daily 09:30 Charlotte (CLT) 12:04 North Eleuthera (ELH)
AA 5278 Non-stop Canadair CRJ 700 (CR7) 2:34 Effective 2026-03-08 through 2026-04-06
Daily 10:40 Memphis (MEM) 13:54 Ronald Reagan Washington (DCA) 2
AA 5278 Non-stop Canadair CRJ 700 (CR7) 2:14 Effective 2026-05-21 through 2026-07-01
Daily 12:44 North Eleuthera (ELH) 15:31 Charlotte (CLT)
AA 5278 Non-stop Canadair CRJ 700 (CR7) 2:47 Effective 2026-03-08 through 2026-04-06
Daily 13:11 Manchester (MHT) 15:40 Charlotte (CLT)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:29 Effective 2026-07-02 through 2026-08-04
Sat 13:48 Ronald Reagan Washington (DCA) 2 15:34 Pensacola (PNS)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:46 Effective 2026-01-10 through 2026-02-07
Sat 13:59 Ronald Reagan Washington (DCA) 2 15:45 Pensacola (PNS)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:46 Effective 2026-02-14 through 2026-03-07
Mon-Fri,Sun 14:52 Ronald Reagan Washington (DCA) 2 16:38 Pensacola (PNS)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:46 Effective 2026-02-12 through 2026-03-06
Mon-Fri,Sun 14:54 Ronald Reagan Washington (DCA) 2 16:40 Pensacola (PNS)
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:46 Effective 2026-01-06 through 2026-02-11
Sat 16:15 Pensacola (PNS) 19:40 Ronald Reagan Washington (DCA) 2
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:25 Effective 2026-02-14 through 2026-03-07
Sat 16:26 Pensacola (PNS) 19:50 Ronald Reagan Washington (DCA) 2
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:24 Effective 2026-01-10 through 2026-02-07
Mon-Fri,Sun 17:08 Pensacola (PNS) 20:33 Ronald Reagan Washington (DCA) 2
AA 5278 Non-stop Canadair CRJ 900 (CR9) 2:25 Effective 2026-02-12 through 2026-03-06
Daily 22:00 Ronald Reagan Washington (DCA) 2 23:54 Grand Rapids (GRR)
AA 5278 Non-stop Canadair CRJ 700 (CR7) 1:54 Effective 2026-09-09 through 2026-10-04
This flight number is listed as serving the following routes:


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American Airlines flight AA 5278: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5278
06:40
Lexington (LEX)

08:20
Charlotte (CLT)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:40, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
06:41
Lexington (LEX)

08:10
Charlotte (CLT)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:29, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
06:52
Lexington (LEX)

08:20
Charlotte (CLT)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:28, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
08:20
Ronald Reagan Washington (DCA) 2

09:54
Memphis (MEM)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:34, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5278
09:00
Charlotte (CLT)

11:29
Manchester (MHT)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:29, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
09:30
Charlotte (CLT)

12:04
North Eleuthera (ELH)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:34, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5278
10:40
Memphis (MEM)

13:54
Ronald Reagan Washington (DCA) 2
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:14, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5278
12:44
North Eleuthera (ELH)

15:31
Charlotte (CLT)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:47, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5278
13:11
Manchester (MHT)

15:40
Charlotte (CLT)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:29, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
13:48
Ronald Reagan Washington (DCA) 2

15:34
Pensacola (PNS)
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:46, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
13:59
Ronald Reagan Washington (DCA) 2

15:45
Pensacola (PNS)
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:46, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
14:52
Ronald Reagan Washington (DCA) 2

16:38
Pensacola (PNS)
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:46, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
14:54
Ronald Reagan Washington (DCA) 2

16:40
Pensacola (PNS)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:46, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
16:15
Pensacola (PNS)

19:40
Ronald Reagan Washington (DCA) 2
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:25, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
16:26
Pensacola (PNS)

19:50
Ronald Reagan Washington (DCA) 2
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:24, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
17:08
Pensacola (PNS)

20:33
Ronald Reagan Washington (DCA) 2
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:25, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5278
22:00
Ronald Reagan Washington (DCA) 2

23:54
Grand Rapids (GRR)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)
This flight number is listed as serving the following routes:
  • Charlotte (CLT) - Manchester (MHT)
  • Charlotte (CLT) - North Eleuthera (ELH)
  • Lexington (LEX) - Charlotte (CLT)
  • Ronald Reagan Washington (DCA) - Grand Rapids (GRR)
  • Ronald Reagan Washington (DCA) - Memphis (MEM)
  • Ronald Reagan Washington (DCA) - Pensacola (PNS)
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