American Airlines flight AA 4646: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 08:05 John Glenn Columbus (CMH) 09:29 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2026-05-21 through 2026-07-01
Sat 10:05 Ronald Reagan Washington (DCA) 2 12:57 Fort Myers (RSW)
AA 4646 Non-stop Embraer EMB 175 (E75) 2:52 Valid until 2026-01-03
Sat 13:27 Fort Myers (RSW) 15:59 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 2:32 Valid until 2026-01-03
Sat 15:45 Atlanta (ATL) N 18:02 New York LaGuardia (LGA) B
AA 4646 Non-stop Embraer EMB 175 (E75) 2:17 Effective 2026-03-14 through 2026-04-04
Mon-Fri,Sun 16:08 Atlanta (ATL) N 18:27 New York LaGuardia (LGA) B
AA 4646 Non-stop Embraer EMB 175 (E75) 2:19 Effective 2026-03-08 through 2026-04-06
Sun 16:14 New York LaGuardia (LGA) B 17:46 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 1:32 Effective 2026-01-11 through 2026-02-08
Mon-Fri 16:17 New York LaGuardia (LGA) B 17:49 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 1:32 Effective 2026-01-06 through 2026-02-11
Sat 21:25 Raleigh/Durham (RDU) 2 22:21 Nashville (BNA)
AA 4646 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2026-02-14 through 2026-03-07
Daily 21:29 New York LaGuardia (LGA) B 23:42 Indianapolis (IND)
AA 4646 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:13 Effective from 2026-10-05
Sun 21:45 Pittsburgh (PIT) 22:50 Chicago O'Hare (ORD) 3
AA 4646 Non-stop Embraer EMB 175 (E75) 2:05 Operates only on 2026-01-04
Tue,Wed 22:00 Raleigh/Durham (RDU) 2 22:59 Nashville (BNA)
AA 4646 Non-stop Embraer EMB 175 (E75) 1:59 Effective 2026-02-17 through 2026-03-04
Mon,Thu,Fri,Sun 22:25 Raleigh/Durham (RDU) 2 23:24 Nashville (BNA)
AA 4646 Non-stop Embraer EMB 175 (E75) 1:59 Effective 2026-02-12 through 2026-03-06
This flight number is listed as serving the following routes:


Feedback - Disclaimer - Privacy
FlightMapper.net Flight Search Countries Airlines
LANGUAGES
American Airlines flight AA 4646: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4646
08:05
John Glenn Columbus (CMH)

09:29
Ronald Reagan Washington (DCA) 2
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
10:05
Ronald Reagan Washington (DCA) 2

12:57
Fort Myers (RSW)
Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:52, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
13:27
Fort Myers (RSW)

15:59
Ronald Reagan Washington (DCA) 2
Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:32, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
15:45
Atlanta (ATL) N

18:02
New York LaGuardia (LGA) B
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:17, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
16:08
Atlanta (ATL) N

18:27
New York LaGuardia (LGA) B
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:19, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
16:14
New York LaGuardia (LGA) B

17:46
Ronald Reagan Washington (DCA) 2
Effective 2026-01-11 through 2026-02-08
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:32, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
16:17
New York LaGuardia (LGA) B

17:49
Ronald Reagan Washington (DCA) 2
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:32, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
21:25
Raleigh/Durham (RDU) 2

22:21
Nashville (BNA)
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:56, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
21:29
New York LaGuardia (LGA) B

23:42
Indianapolis (IND)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:13, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Flights:
American Airlines AA4646
21:45
Pittsburgh (PIT)

22:50
Chicago O'Hare (ORD) 3
Operates only on 2026-01-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
22:00
Raleigh/Durham (RDU) 2

22:59
Nashville (BNA)
Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:59, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4646
22:25
Raleigh/Durham (RDU) 2

23:24
Nashville (BNA)
Effective 2026-02-12 through 2026-03-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:59, non-stop
Embraer EMB 175 (E75)
This flight number is listed as serving the following routes:
  • Atlanta (ATL) - New York LaGuardia (LGA)
  • Fort Myers (RSW) - Ronald Reagan Washington (DCA)
  • John Glenn Columbus (CMH) - Ronald Reagan Washington (DCA)
  • New York LaGuardia (LGA) - Indianapolis (IND)
  • New York LaGuardia (LGA) - Ronald Reagan Washington (DCA)
  • Pittsburgh (PIT) - Chicago O'Hare (ORD)
  • Raleigh/Durham (RDU) - Nashville (BNA)
All American Airlines flights
Feedback     -     Disclaimer     -     Privacy