American Airlines flight AA 4643: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 08:05 Chicago O'Hare (ORD) 3 11:28 Norfolk (ORF)
AA 4643 Non-stop Embraer EMB 175 (E75) 2:23 Effective 2026-05-21 through 2026-08-04
Daily 08:20 Ronald Reagan Washington (DCA) 2 10:14 Columbia (CAE)
AA 4643 Non-stop Embraer EMB 175 (E75) 1:54 Effective 2026-09-09 through 2026-10-04
Daily 10:48 Columbia (CAE) 12:18 Ronald Reagan Washington (DCA) 2
AA 4643 Non-stop Embraer EMB 175 (E75) 1:30 Effective 2026-09-09 through 2026-10-04
Daily 11:58 Norfolk (ORF) 14:34 Chicago O'Hare (ORD) 3
AA 4643 Non-stop Embraer EMB 175 (E75) 3:36 Effective 2026-05-21 through 2026-08-04
Daily 15:49 Indianapolis (IND) 17:44 Philadelphia (PHL)
AA 4643 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2026-01-06 through 2026-02-11
Daily 16:24 Indianapolis (IND) 18:19 Philadelphia (PHL)
AA 4643 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2026-02-12 through 2026-03-07
Daily 16:24 Indianapolis (IND) 18:25 Philadelphia (PHL)
AA 4643 Non-stop Embraer EMB 175 (E75) 2:01 Effective 2026-03-08 through 2026-04-06
Sun 20:46 Chicago O'Hare (ORD) 3 23:49 Rochester (ROC)
AA 4643 Non-stop Embraer EMB 175 (E75) 2:03 Operates only on 2026-01-04
Mon,Tue,Thu-Sat 21:15 Chicago O'Hare (ORD) 3 00:15 Rochester (ROC)
AA 4643 Non-stop Embraer EMB 175 (E75) 2:00 Valid until 2026-01-05
The flight arrives 1 day after departure.
This flight number is listed as serving the following routes:


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American Airlines flight AA 4643: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4643
08:05
Chicago O'Hare (ORD) 3

11:28
Norfolk (ORF)
Effective 2026-05-21 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:23, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
08:20
Ronald Reagan Washington (DCA) 2

10:14
Columbia (CAE)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
10:48
Columbia (CAE)

12:18
Ronald Reagan Washington (DCA) 2
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:30, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
11:58
Norfolk (ORF)

14:34
Chicago O'Hare (ORD) 3
Effective 2026-05-21 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:36, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
15:49
Indianapolis (IND)

17:44
Philadelphia (PHL)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
16:24
Indianapolis (IND)

18:19
Philadelphia (PHL)
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
16:24
Indianapolis (IND)

18:25
Philadelphia (PHL)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:01, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
20:46
Chicago O'Hare (ORD) 3

23:49
Rochester (ROC)
Operates only on 2026-01-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:03, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4643
21:15
Chicago O'Hare (ORD) 3

00:15(+1)
Rochester (ROC)
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
-
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
The flight arrives 1 day after departure.
This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Norfolk (ORF)
  • Chicago O'Hare (ORD) - Rochester (ROC)
  • Indianapolis (IND) - Philadelphia (PHL)
  • Ronald Reagan Washington (DCA) - Columbia (CAE)
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