Alaska Airlines flight AS 4581: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 06:30 Saint Louis (STL) 1 08:47 Los Angeles (LAX)
AS 4581 Non-stop Embraer EMB 175 (E75) 4:17 Effective 2026-02-12 through 2026-03-07
Codeshare flight, operated by American Airlines.(AA 6195)
Daily 06:30 Saint Louis (STL) 1 08:37 Los Angeles (LAX)
AS 4581 Non-stop Embraer EMB 175 (E75) 4:07 Effective 2026-04-07 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 6216)
Daily 06:30 Saint Louis (STL) 1 08:22 Los Angeles (LAX)
AS 4581 Non-stop Embraer EMB 175 (E75) 3:52 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 6426)
Daily 07:04 Saint Louis (STL) 1 09:20 Los Angeles (LAX)
AS 4581 Non-stop Embraer EMB 175 (E75) 4:16 Effective 2026-01-06 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 4885)
Mon,Thu-Sun 12:49 Denver (DEN) 14:31 Los Angeles (LAX)
AS 4581 Non-stop Canadair CRJ 700 (CR7) 2:42 Effective 2026-03-08 through 2026-04-06
Codeshare flight, operated by American Airlines.(AA 6429)
Tue,Wed 13:13 Denver (DEN) 14:55 Los Angeles (LAX)
AS 4581 Non-stop Canadair CRJ 700 (CR7) 2:42 Effective 2026-03-10 through 2026-04-01
Codeshare flight, operated by American Airlines.(AA 6429)
Daily 20:20 Phoenix Sky Harbor (PHX) 4 22:52 Medford (MFR)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:32 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 6373)
Daily 20:55 Phoenix Sky Harbor (PHX) 4 23:24 Medford (MFR)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:29 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 6373)
This flight number is listed as serving the following routes:
Alaska Airlines flight AS 4581: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:

Alaska Airlines AS4581
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6195)
Duration: 4:17, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS4581
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6216)
Duration: 4:07, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS4581
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6426)
Duration: 3:52, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS4581
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4885)
Duration: 4:16, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS4581
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6429)
Duration: 2:42, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS4581
Effective 2026-03-10 through 2026-04-01
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 6429)
Duration: 2:42, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS4581
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6373)
Duration: 2:32, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS4581
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6373)
Duration: 2:29, non-stop
Embraer EMB 175 (E75)
This flight number is listed as serving the following routes:
  • Denver (DEN) - Los Angeles (LAX)
  • Phoenix Sky Harbor (PHX) - Medford (MFR)
  • Saint Louis (STL) - Los Angeles (LAX)