Alaska Airlines flight AS 4421: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Mon,Thu,Fri 06:00 Chicago O'Hare (ORD) 3 09:31 Boston Logan (BOS) B
AS 4421 Non-stop Embraer EMB 175 (E75) 2:31 Effective 2026-03-09 through 2026-03-16
Codeshare flight, operated by American Airlines.(AA 4358)
Mon,Sat,Sun 06:25 Miami (MIA) 08:47 Chicago O'Hare (ORD) 3
AS 4421 Non-stop Boeing 737-800 (738) 3:22 Effective 2026-01-03 through 2026-01-05
Codeshare flight, operated by American Airlines.(AA 839)
Tue 07:10 Philadelphia (PHL) 10:21 Miami (MIA)
AS 4421 Non-stop Airbus A319 (319) 3:11 Operates only on 2026-01-06
Codeshare flight, operated by American Airlines.(AA 1005)
Mon,Thu,Fri 10:01 Boston Logan (BOS) B 12:07 Chicago O'Hare (ORD) 3
AS 4421 Non-stop Embraer EMB 175 (E75) 3:06 Effective 2026-03-09 through 2026-03-16
Codeshare flight, operated by American Airlines.(AA 4358)
Daily 18:40 Philadelphia (PHL) 21:25 Miami (MIA)
AS 4421 Non-stop Airbus A321 (321) 2:45 Effective 2026-04-07 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 1525)
Daily 18:40 Philadelphia (PHL) 21:46 Miami (MIA)
AS 4421 Non-stop Boeing 737-800 (738) 3:06 Effective 2026-05-21 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 1181)
Daily 18:40 Philadelphia (PHL) 21:43 Miami (MIA)
AS 4421 Non-stop Boeing 737-800 (738) 3:03 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 1181)
Daily 18:50 Philadelphia (PHL) 22:00 Miami (MIA)
AS 4421 Non-stop Boeing 737-800 (738) 3:10 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 1181)
Daily 19:45 Ronald Reagan Washington (DCA) 2 21:57 Jacksonville (JAX)
AS 4421 Non-stop Airbus A319 (319) 2:12 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 2073)
This flight number is listed as serving the following routes:


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Alaska Airlines flight AS 4421: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS4421
06:00
Chicago O'Hare (ORD) 3

09:31
Boston Logan (BOS) B
Effective 2026-03-09 through 2026-03-16
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 4358)
Duration: 2:31, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS4421
06:25
Miami (MIA)

08:47
Chicago O'Hare (ORD) 3
Effective 2026-01-03 through 2026-01-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 839)
Duration: 3:22, non-stop
Boeing 737-800 (738)
Direct Codeshare Flights:
Alaska Airlines AS4421
07:10
Philadelphia (PHL)

10:21
Miami (MIA)
Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 1005)
Duration: 3:11, non-stop
Airbus A319 (319)
Direct Codeshare Flights:
Alaska Airlines AS4421
10:01
Boston Logan (BOS) B

12:07
Chicago O'Hare (ORD) 3
Effective 2026-03-09 through 2026-03-16
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 4358)
Duration: 3:06, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS4421
18:40
Philadelphia (PHL)

21:25
Miami (MIA)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1525)
Duration: 2:45, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
Alaska Airlines AS4421
18:40
Philadelphia (PHL)

21:46
Miami (MIA)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1181)
Duration: 3:06, non-stop
Boeing 737-800 (738)
Direct Codeshare Flights:
Alaska Airlines AS4421
18:40
Philadelphia (PHL)

21:43
Miami (MIA)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1181)
Duration: 3:03, non-stop
Boeing 737-800 (738)
Direct Codeshare Flights:
Alaska Airlines AS4421
18:50
Philadelphia (PHL)

22:00
Miami (MIA)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1181)
Duration: 3:10, non-stop
Boeing 737-800 (738)
Direct Codeshare Flights:
Alaska Airlines AS4421
19:45
Ronald Reagan Washington (DCA) 2

21:57
Jacksonville (JAX)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 2073)
Duration: 2:12, non-stop
Airbus A319 (319)
This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Boston Logan (BOS)
  • Miami (MIA) - Chicago O'Hare (ORD)
  • Philadelphia (PHL) - Miami (MIA)
  • Ronald Reagan Washington (DCA) - Jacksonville (JAX)
All Alaska Airlines flights
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