American Airlines flight AA 5381: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 07:15 Charlotte (CLT) 08:10 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:55 Effective 2024-12-05 through 2024-12-18
Daily 09:00 Charlotte (CLT) 09:53 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:53 Effective 2025-03-09 through 2025-04-03
Daily 09:00 Charlotte (CLT) 09:50 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:50 Effective 2025-05-05 through 2025-06-04
Thu,Fri 09:05 Charlotte (CLT) 09:56 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:51 Effective 2024-11-28 through 2024-11-29
Daily 09:05 Charlotte (CLT) 10:02 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:57 Effective 2024-12-19 through 2025-01-06
Daily 09:05 Charlotte (CLT) 09:59 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:54 Effective 2025-02-13 through 2025-03-05
Thu-Sat 09:05 Charlotte (CLT) 09:53 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:48 Effective 2025-03-06 through 2025-03-08
Daily 09:05 Charlotte (CLT) 09:56 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:51 Effective 2025-04-04 through 2025-05-04
Daily 09:39 Charlotte (CLT) 10:41 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:02 Effective 2024-11-05 through 2024-11-27
Mon-Wed,Sat,Sun 09:39 Charlotte (CLT) 10:41 Greenville/Spartanburg (GSP)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:02 Effective 2024-11-30 through 2024-12-04
Daily 11:07 Greenville/Spartanburg (GSP) 12:19 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:12 Effective 2024-09-04 through 2024-10-06
Daily 11:12 Greenville/Spartanburg (GSP) 12:18 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:06 Effective 2024-10-07 through 2024-10-28
Mon,Wed-Sun 11:12 Greenville/Spartanburg (GSP) 12:18 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:06 Effective 2024-10-30 through 2024-11-04
Daily 11:13 Greenville/Spartanburg (GSP) 12:20 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:07 Valid until 2024-09-03
Tue 11:13 Greenville/Spartanburg (GSP) 12:19 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:06 Operates only on 2024-10-29
Sat 11:13 Greenville/Spartanburg (GSP) 12:18 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:05 Effective 2024-11-09 through 2024-11-16
Mon-Fri,Sun 11:14 Greenville/Spartanburg (GSP) 12:19 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:05 Effective 2024-11-05 through 2024-11-22
Mon-Wed,Sat,Sun 11:14 Greenville/Spartanburg (GSP) 12:19 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:05 Effective 2024-11-23 through 2024-12-04
Thu,Fri 11:21 Greenville/Spartanburg (GSP) 12:25 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:04 Effective 2024-11-28 through 2024-11-29
Daily 11:21 Greenville/Spartanburg (GSP) 12:25 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:04 Effective 2025-04-04 through 2025-05-04
Daily 11:22 Greenville/Spartanburg (GSP) 12:25 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:03 Effective from 2025-06-05
Daily 11:23 Greenville/Spartanburg (GSP) 12:25 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:02 Effective 2024-12-19 through 2025-01-06
Daily 11:23 Greenville/Spartanburg (GSP) 12:25 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:02 Effective 2025-05-05 through 2025-06-04
Thu-Sat 11:25 Greenville/Spartanburg (GSP) 12:30 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:05 Effective 2025-03-06 through 2025-03-08
Daily 11:25 Greenville/Spartanburg (GSP) 12:25 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2025-03-09 through 2025-04-03
Daily 11:27 Greenville/Spartanburg (GSP) 12:25 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 0:58 Effective 2025-02-13 through 2025-03-05
Daily 12:49 Greenville/Spartanburg (GSP) 13:50 Charlotte (CLT)
AA 5381 Non-stop Canadair CRJ 900 (CR9) 1:01 Effective 2024-12-05 through 2024-12-18
This flight number is listed as serving the following routes:


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American Airlines flight AA 5381: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5381
07:15
Charlotte (CLT)

08:10
Greenville/Spartanburg (GSP)
Effective 2024-12-05 through 2024-12-18
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:55, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:00
Charlotte (CLT)

09:53
Greenville/Spartanburg (GSP)
Effective 2025-03-09 through 2025-04-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:53, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:00
Charlotte (CLT)

09:50
Greenville/Spartanburg (GSP)
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:50, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:05
Charlotte (CLT)

09:56
Greenville/Spartanburg (GSP)
Effective 2024-11-28 through 2024-11-29
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 0:51, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:05
Charlotte (CLT)

10:02
Greenville/Spartanburg (GSP)
Effective 2024-12-19 through 2025-01-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:57, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:05
Charlotte (CLT)

09:59
Greenville/Spartanburg (GSP)
Effective 2025-02-13 through 2025-03-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:54, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:05
Charlotte (CLT)

09:53
Greenville/Spartanburg (GSP)
Effective 2025-03-06 through 2025-03-08
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
Sun
-
Duration: 0:48, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:05
Charlotte (CLT)

09:56
Greenville/Spartanburg (GSP)
Effective 2025-04-04 through 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:51, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:39
Charlotte (CLT)

10:41
Greenville/Spartanburg (GSP)
Effective 2024-11-05 through 2024-11-27
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:02, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
09:39
Charlotte (CLT)

10:41
Greenville/Spartanburg (GSP)
Effective 2024-11-30 through 2024-12-04
Mon
Tue
Wed
Thu
-
Fri
-
Sat
Sun
Duration: 1:02, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:07
Greenville/Spartanburg (GSP)

12:19
Charlotte (CLT)
Effective 2024-09-04 through 2024-10-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:12, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:12
Greenville/Spartanburg (GSP)

12:18
Charlotte (CLT)
Effective 2024-10-07 through 2024-10-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:06, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:12
Greenville/Spartanburg (GSP)

12:18
Charlotte (CLT)
Effective 2024-10-30 through 2024-11-04
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 1:06, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:13
Greenville/Spartanburg (GSP)

12:20
Charlotte (CLT)
Valid until 2024-09-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:07, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:13
Greenville/Spartanburg (GSP)

12:19
Charlotte (CLT)
Operates only on 2024-10-29
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:06, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:13
Greenville/Spartanburg (GSP)

12:18
Charlotte (CLT)
Effective 2024-11-09 through 2024-11-16
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:05, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:14
Greenville/Spartanburg (GSP)

12:19
Charlotte (CLT)
Effective 2024-11-05 through 2024-11-22
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:05, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:14
Greenville/Spartanburg (GSP)

12:19
Charlotte (CLT)
Effective 2024-11-23 through 2024-12-04
Mon
Tue
Wed
Thu
-
Fri
-
Sat
Sun
Duration: 1:05, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:21
Greenville/Spartanburg (GSP)

12:25
Charlotte (CLT)
Effective 2024-11-28 through 2024-11-29
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 1:04, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:21
Greenville/Spartanburg (GSP)

12:25
Charlotte (CLT)
Effective 2025-04-04 through 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:04, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:22
Greenville/Spartanburg (GSP)

12:25
Charlotte (CLT)
Effective from 2025-06-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:03, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:23
Greenville/Spartanburg (GSP)

12:25
Charlotte (CLT)
Effective 2024-12-19 through 2025-01-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:02, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:23
Greenville/Spartanburg (GSP)

12:25
Charlotte (CLT)
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:02, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:25
Greenville/Spartanburg (GSP)

12:30
Charlotte (CLT)
Effective 2025-03-06 through 2025-03-08
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
Sun
-
Duration: 1:05, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:25
Greenville/Spartanburg (GSP)

12:25
Charlotte (CLT)
Effective 2025-03-09 through 2025-04-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
11:27
Greenville/Spartanburg (GSP)

12:25
Charlotte (CLT)
Effective 2025-02-13 through 2025-03-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:58, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5381
12:49
Greenville/Spartanburg (GSP)

13:50
Charlotte (CLT)
Effective 2024-12-05 through 2024-12-18
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:01, non-stop
Canadair CRJ 900 (CR9)
This flight number is listed as serving the following routes:
  • Greenville/Spartanburg (GSP) - Charlotte (CLT)
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