American Airlines flight AA 2221: Multiple routes

Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 08:55 Charlotte (CLT) 10:32 Indianapolis (IND)
AA 2221 Non-stop Boeing 737-800 (738) 1:37 Effective 2025-05-05 through 2025-06-04
Daily 09:00 Charlotte (CLT) 10:49 Indianapolis (IND)
AA 2221 Non-stop Boeing 737-800 (738) 1:49 Effective 2025-04-04 through 2025-05-04
Mon,Thu,Fri,Sun 12:00 Indianapolis (IND) 13:44 Charlotte (CLT)
AA 2221 Non-stop Boeing 737-800 (738) 1:44 Effective 2024-09-05 through 2024-10-06
Tue 12:05 Indianapolis (IND) 13:48 Charlotte (CLT)
AA 2221 Non-stop Airbus A321 (321) 1:43 Effective 2024-09-17 through 2024-09-24
Daily 12:10 Indianapolis (IND) 13:49 Charlotte (CLT)
AA 2221 Non-stop Boeing 737-800 (738) 1:39 Effective 2024-10-07 through 2024-11-01
Mon,Sun 12:10 Indianapolis (IND) 13:49 Charlotte (CLT)
AA 2221 Non-stop Boeing 737-800 (738) 1:39 Effective 2024-11-03 through 2024-11-04
Sat 12:11 Indianapolis (IND) 13:50 Charlotte (CLT)
AA 2221 Non-stop Airbus A321 (321) 1:39 Operates only on 2024-11-02
Mon-Fri,Sun 12:15 Indianapolis (IND) 13:54 Charlotte (CLT)
AA 2221 Non-stop Boeing 737-800 (738) 1:39 Valid until 2024-09-03
Daily 12:16 Indianapolis (IND) 14:00 Charlotte (CLT)
AA 2221 Non-stop Boeing 737-800 (738) 1:44 Effective from 2025-06-05
Tue,Wed 12:17 Indianapolis (IND) 14:00 Charlotte (CLT)
AA 2221 Non-stop Airbus A321 (321) 1:43 Effective 2024-09-04 through 2024-09-11
Wed 12:17 Indianapolis (IND) 14:00 Charlotte (CLT)
AA 2221 Non-stop Airbus A321 (321) 1:43 Effective 2024-09-18 through 2024-09-25
Tue,Wed 12:17 Indianapolis (IND) 14:00 Charlotte (CLT)
AA 2221 Non-stop Airbus A321 (321) 1:43 Effective 2024-10-01 through 2024-10-02
Daily 12:19 Indianapolis (IND) 14:00 Charlotte (CLT)
AA 2221 Non-stop Boeing 737-800 (738) 1:41 Effective 2025-04-04 through 2025-06-04
Sat 13:33 Indianapolis (IND) 15:18 Charlotte (CLT)
AA 2221 Non-stop Airbus A321 (321) 1:45 Effective 2024-09-07 through 2024-10-05
Daily 16:45 Atlanta (ATL) N 18:45 Los Angeles (LAX)
AA 2221 Non-stop Airbus A321 (321) 5:00 Effective 2024-11-05 through 2024-11-27
Mon-Wed,Sat,Sun 16:45 Atlanta (ATL) N 18:45 Los Angeles (LAX)
AA 2221 Non-stop Airbus A321 (321) 5:00 Effective 2024-11-30 through 2024-12-04
Daily 16:50 Atlanta (ATL) N 19:01 Los Angeles (LAX)
AA 2221 Non-stop Airbus A321 (321) 5:11 Effective 2025-02-13 through 2025-03-05
Daily 16:50 Atlanta (ATL) N 18:57 Los Angeles (LAX)
AA 2221 Non-stop Airbus A321 (321) 5:07 Effective 2025-03-06 through 2025-04-03
Thu,Fri 17:10 Atlanta (ATL) N 19:10 Los Angeles (LAX)
AA 2221 Non-stop Airbus A321 (321) 5:00 Effective 2024-11-28 through 2024-11-29
Daily 17:10 Atlanta (ATL) N 19:12 Los Angeles (LAX)
AA 2221 Non-stop Airbus A321 (321) 5:02 Effective 2024-12-05 through 2025-01-06
Daily 17:10 Atlanta (ATL) N 19:11 Los Angeles (LAX)
AA 2221 Non-stop Airbus A321 (321) 5:01 Effective 2025-01-07 through 2025-02-12
This flight number is listed as serving the following routes:


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American Airlines flight AA 2221: Multiple routes
Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA2221
08:55
Charlotte (CLT)

10:32
Indianapolis (IND)
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:37, non-stop
Boeing 737-800 (738)
American Airlines AA2221
09:00
Charlotte (CLT)

10:49
Indianapolis (IND)
Effective 2025-04-04 through 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:49, non-stop
Boeing 737-800 (738)
American Airlines AA2221
12:00
Indianapolis (IND)

13:44
Charlotte (CLT)
Effective 2024-09-05 through 2024-10-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:44, non-stop
Boeing 737-800 (738)
American Airlines AA2221
12:05
Indianapolis (IND)

13:48
Charlotte (CLT)
Effective 2024-09-17 through 2024-09-24
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:43, non-stop
Airbus A321 (321)
American Airlines AA2221
12:10
Indianapolis (IND)

13:49
Charlotte (CLT)
Effective 2024-10-07 through 2024-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Boeing 737-800 (738)
American Airlines AA2221
12:10
Indianapolis (IND)

13:49
Charlotte (CLT)
Effective 2024-11-03 through 2024-11-04
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:39, non-stop
Boeing 737-800 (738)
American Airlines AA2221
12:11
Indianapolis (IND)

13:50
Charlotte (CLT)
Operates only on 2024-11-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:39, non-stop
Airbus A321 (321)
American Airlines AA2221
12:15
Indianapolis (IND)

13:54
Charlotte (CLT)
Valid until 2024-09-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:39, non-stop
Boeing 737-800 (738)
American Airlines AA2221
12:16
Indianapolis (IND)

14:00
Charlotte (CLT)
Effective from 2025-06-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Boeing 737-800 (738)
American Airlines AA2221
12:17
Indianapolis (IND)

14:00
Charlotte (CLT)
Effective 2024-09-04 through 2024-09-11
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:43, non-stop
Airbus A321 (321)
American Airlines AA2221
12:17
Indianapolis (IND)

14:00
Charlotte (CLT)
Effective 2024-09-18 through 2024-09-25
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:43, non-stop
Airbus A321 (321)
American Airlines AA2221
12:17
Indianapolis (IND)

14:00
Charlotte (CLT)
Effective 2024-10-01 through 2024-10-02
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:43, non-stop
Airbus A321 (321)
American Airlines AA2221
12:19
Indianapolis (IND)

14:00
Charlotte (CLT)
Effective 2025-04-04 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Boeing 737-800 (738)
American Airlines AA2221
13:33
Indianapolis (IND)

15:18
Charlotte (CLT)
Effective 2024-09-07 through 2024-10-05
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:45, non-stop
Airbus A321 (321)
American Airlines AA2221
16:45
Atlanta (ATL) N

18:45
Los Angeles (LAX)
Effective 2024-11-05 through 2024-11-27
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:00, non-stop
Airbus A321 (321)
American Airlines AA2221
16:45
Atlanta (ATL) N

18:45
Los Angeles (LAX)
Effective 2024-11-30 through 2024-12-04
Mon
Tue
Wed
Thu
-
Fri
-
Sat
Sun
Duration: 5:00, non-stop
Airbus A321 (321)
American Airlines AA2221
16:50
Atlanta (ATL) N

19:01
Los Angeles (LAX)
Effective 2025-02-13 through 2025-03-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:11, non-stop
Airbus A321 (321)
American Airlines AA2221
16:50
Atlanta (ATL) N

18:57
Los Angeles (LAX)
Effective 2025-03-06 through 2025-04-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:07, non-stop
Airbus A321 (321)
American Airlines AA2221
17:10
Atlanta (ATL) N

19:10
Los Angeles (LAX)
Effective 2024-11-28 through 2024-11-29
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 5:00, non-stop
Airbus A321 (321)
American Airlines AA2221
17:10
Atlanta (ATL) N

19:12
Los Angeles (LAX)
Effective 2024-12-05 through 2025-01-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:02, non-stop
Airbus A321 (321)
American Airlines AA2221
17:10
Atlanta (ATL) N

19:11
Los Angeles (LAX)
Effective 2025-01-07 through 2025-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:01, non-stop
Airbus A321 (321)
This flight number is listed as serving the following routes:
  • Atlanta (ATL) - Los Angeles (LAX)
  • Indianapolis (IND) - Charlotte (CLT)
All American Airlines flights
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