Alaska Airlines flight AS 6221: Ronald Reagan Washington - Greenville/Spartanburg

Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 17:04 Ronald Reagan Washington (DCA) 2 18:44 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 900 (CR9) 1:40 Effective 2025-10-06 through 2025-11-01
Codeshare flight, operated by American Airlines.(AA 5274)
Sat,Sun 17:10 Ronald Reagan Washington (DCA) 2 18:48 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 900 (CR9) 1:38 Effective 2025-10-04 through 2025-10-05
Codeshare flight, operated by American Airlines.(AA 5608)
Daily 17:15 Ronald Reagan Washington (DCA) 2 19:00 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2025-12-03 through 2025-12-17
Codeshare flight, operated by American Airlines.(AA 5274)
Mon-Fri,Sun 17:29 Ronald Reagan Washington (DCA) 2 19:06 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:37 Effective 2025-06-05 through 2025-07-04
Codeshare flight, operated by American Airlines.(AA 5274)
Mon-Fri,Sun 17:34 Ronald Reagan Washington (DCA) 2 19:10 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:36 Valid until 2025-05-04
Codeshare flight, operated by American Airlines.(AA 5608)
Daily 20:01 Ronald Reagan Washington (DCA) 2 21:45 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 900 (CR9) 1:44 Effective 2025-09-03 through 2025-10-03
Codeshare flight, operated by American Airlines.(AA 5497)
Mon-Fri,Sun 20:03 Ronald Reagan Washington (DCA) 2 21:53 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:50 Effective 2025-05-05 through 2025-06-04
Codeshare flight, operated by American Airlines.(AA 5497)
Sat 20:20 Ronald Reagan Washington (DCA) 2 21:53 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:33 Effective 2025-06-07 through 2025-06-28
Codeshare flight, operated by American Airlines.(AA 5497)
Wed-Sun 20:20 Ronald Reagan Washington (DCA) 2 22:01 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:41 Effective 2025-07-05 through 2025-08-03
Codeshare flight, operated by American Airlines.(AA 5497)
Daily 20:52 Ronald Reagan Washington (DCA) 2 22:30 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 700 (CR7) 1:38 Effective 2026-01-06 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 5576)
Mon-Fri,Sun 22:00 Ronald Reagan Washington (DCA) 2 23:33 Greenville/Spartanburg (GSP)
AS 6221 Non-stop Canadair CRJ 900 (CR9) 1:33 Effective 2025-08-20 through 2025-09-02
Codeshare flight, operated by American Airlines.(AA 5044)
Alaska Airlines flight AS 6221:
Ronald Reagan Washington - Greenville/Spartanburg
Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:

Alaska Airlines AS6221
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5274)
Duration: 1:40, non-stop
Canadair CRJ 900 (CR9)

Alaska Airlines AS6221
Effective 2025-10-04 through 2025-10-05
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5608)
Duration: 1:38, non-stop
Canadair CRJ 900 (CR9)

Alaska Airlines AS6221
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5274)
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS6221
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5274)
Duration: 1:37, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS6221
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5608)
Duration: 1:36, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS6221
Effective 2025-09-03 through 2025-10-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5497)
Duration: 1:44, non-stop
Canadair CRJ 900 (CR9)

Alaska Airlines AS6221
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5497)
Duration: 1:50, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS6221
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5497)
Duration: 1:33, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS6221
Effective 2025-07-05 through 2025-08-03
Mon
-
Tue
-
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5497)
Duration: 1:41, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS6221
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5576)
Duration: 1:38, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS6221
Effective 2025-08-20 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5044)
Duration: 1:33, non-stop
Canadair CRJ 900 (CR9)
  • AS 6221 is a domestic flight departing from the Ronald Reagan Washington airport (DCA) and arriving at Greenville/Spartanburg airport (GSP).
  • The flight distance is 395 miles, or 635 km.
  • The timezone of both the departure and the arrival airports is UTC-5 . Current time at both airports is (loading...).
  • For direct flights, the flight time varies between 1:33 and 1:50.