Alaska Airlines
flight
AS 4378:
Multiple routes
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS4378
Operates only on 2026-01-06
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Codeshare flight, operated by American Airlines.
(AA 3472)
Duration: 1:22, non-stop Embraer EMB 170 / EMB 175 (E70)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 6441)
Duration: 0:59, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 6441)
Duration: 1:10, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 6441)
Duration: 1:02, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 6441)
Duration: 0:58, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 6441)
Duration: 0:56, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-02-14 through 2026-03-07
Mon
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Tue
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Sun
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Codeshare flight, operated by American Airlines.
(AA 4516)
Duration: 2:25, non-stop Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS4378
Operates only on 2026-03-14
Mon
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Tue
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Wed
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Thu
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Fri
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Sat
Sun
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Codeshare flight, operated by American Airlines.
(AA 4516)
Duration: 2:30, non-stop Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-03-08 through 2026-03-20
Mon
Tue
Wed
Thu
Fri
Sat
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Sun
Codeshare flight, operated by American Airlines.
(AA 6257)
Duration: 1:16, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-03-21 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 6257)
Duration: 1:16, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-01-08 through 2026-02-10
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 6245)
Duration: 1:44, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-02-12 through 2026-03-06
Mon
Tue
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Wed
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Thu
Fri
Sat
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Sun
Codeshare flight, operated by American Airlines.
(AA 6245)
Duration: 1:24, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-02-17 through 2026-03-04
Mon
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Tue
Wed
Thu
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Fri
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Sat
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Sun
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Codeshare flight, operated by American Airlines.
(AA 6245)
Duration: 1:24, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Operates only on 2026-02-11
Mon
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Tue
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Wed
Thu
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Fri
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Sat
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Sun
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Codeshare flight, operated by American Airlines.
(AA 6245)
Duration: 1:44, non-stop Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS4378
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines.
(AA 4177)
Duration: 2:08, non-stop Embraer EMB 170 / EMB 175 (E70)
Direct Codeshare Flights:
Alaska Airlines AS4378
Valid until 2026-01-05
Mon
Tue
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Wed
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Thu
Fri
Sat
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Sun
Codeshare flight, operated by American Airlines.
(AA 3721)
Duration: 1:25, non-stop Embraer EMB 170 / EMB 175 (E70)
This flight number is listed as serving the following routes:
- Flagstaff Pulliam, Grand Canyon (FLG) - Phoenix Sky Harbor (PHX)
- Grand Rapids (GRR) - Chicago O'Hare (ORD)
- Kansas City (MCI) - Chicago O'Hare (ORD)
- Memphis (MEM) - Philadelphia (PHL)
- Moline (MLI) - Chicago O'Hare (ORD)
- Oklahoma City (OKC) - Chicago O'Hare (ORD)